Physiogel. Help your patients restore skin balance and well-being

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1 DAILY CARE FOR DRY, SENSITIVE AND IRRITATED SKIN Help your patients restore skin balance and well-being Hypoallergenic and non-comedogenic. No fragrances, preservatives, dyes or recognised irritants

2 DMS * a well-tolerated moisturizing base Unique combination of ingredients to protect and soothe dry, sensitive and irritated skin A.I. Cream PEA # : naturally occurring ingredient with anti-inflammatory properties (2) Unique formulation Lipid film** structured in layers to mimic the skin Properties: QMoisturizing (2) QSoothing (2) In a DMS base (2) Proven benefits for symptoms of irritated and reactive skin ##(3) Mean Symptom Scores (Physicians' Assessments) Clinically tested Start of study End of study Q No penetration into deeper skin layers (1) Gentle on the epidermis Q Repair of the lipid barrier Helps maintain hydration of the skin 0 Dryness n = 2269 Redness n = 2263 Itch n = 2265 Evaluation by doctors on 4-point scale Where 0 = absence of symptoms and 3 = severe symptoms. p < 0.001vs start of study. *DMS: Derma Membrane Structure **Vegetable-based lipids: ceramides, hydrogenated lecithin (phospholipid), squalane, triglyceride, sterol 1. Wohlrab J., Donald A., Albrecht M. Influence of Hydrogenated Phosphatidylcholine (HPC)-Cream vs. Emulsifier-Cream on the structure of the lipid Skin-Lipid Barrier. Abstract. # Palmitoylethanolamide ## This was a multicenter, observational, non-controlled, prospective cohort study conducted to yield data from physicians and patients with patients 2 to 70 years of age with mild-to-moderate atopic eczema on the efficacy, safety, and acceptance of the study cream ( A.I. Cream) under daily life conditions for 4 to 6 weeks of use. 2. Lambert DM, et al. The palmitoylethanolamide family: a new class of antiinflammatory agents? Curr Med Chem Mar;9(6): Eberlein B., et al. Adjuvant treatment of atopic eczema: assessment of an emollient containing N-palmitoylethanolamine (ATOPA study). J Eur Acad Dermatol Venereol. 2008;22(1):73-82.

3 Focus on daily facial and body care Dry and sensitive skin Cream Dry, irritated and reactive skin A.I. Cream Daily care to be applied morning and evening QRepairs the lipid barrier with DMS QHelps to rehydrate dry skin QNo fragrances, preservatives or dyes Daily care to be applied morning and evening QAll the advantages of Physiogel Cream QContains PEA to protect against irritation and redness due to reactive skin (1,2) QReduces itch Also for the body: Body Lotion Also for the body: A.I. Balm QIdeal for the entire body QTo be applied morning and evening QFormulated for application to large areas 1. Lambert DM, et al. The palmitoylethanolamide family: a new class of antiinflammatory agents? Curr Med Chem Mar;9(6): Eberlein B, et al. Adjuvant treatment of atopic eczema: assessment of an emollient containing N-palmitoylethanolamine (ATOPA study). J Eur Acad Dermatol Venereol. 2008;22(1):73-82.

4 Focus on daily cleansing care Extra-gentle cleansing cream Shower-Cream Sensitive and itchy scalp Shampoo-Plus With DMS, for protection from the moment you take your shower Also for the face: Dermo-Cleanser Apply to wet hair. Work in and then rinse thoroughly Minimal foam produced Daily use Non-rinse dermo-cleanser and make up remover Non-drying formula QSoap free, contains sodium cocoylisethionate, a cleansing and soothing ingredient This product contains parabens. This product does not contain DMS QHypoallergenic QCombines 3 mild surfactants, gentle on the skin and scalp QContains a conditioning agent and provitamin B5 for easy untangling and glossy, soft hair with volume QNo fragrances, parabens, colorings, or phenoxyethanol This product does not contain DMS

5 Helps restore skin balance & well-being Redness & Irritation Dry, irritated and reactive skin A.I. Cream Very dry, irritated and reactive skin Dry Dry and sensitive skin Body Lotion A.I. Lotion A.I. Balm Latest addition to the range Very dry and sensitive skin Very Dry Cream Sensitivity Intensive QHypoallergenic and non-comedogenic No fragrances, preservatives, dyes or recognised irritants QMoisturizing base that is skin-compatible Hydrogenated lecithin + DMS Other formulations for daily cleansing care Shower-Cream Dermo-Cleanser * Shampoo-Plus * Contains parabens Date of preparation: April 2011 SEU/PSG/0002/11

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