PRODUCT DETAIL MANUAL

Transcription

1 PRODUCT DETAIL MANUAL Transforming solutions for beautiful and healthy looking skin

2 TRANSFORMING SOLUTIONS FOR BEAUTIFUL AND HEALTHY LOOKING SKIN Glytone was born in the United States in 1943 when 2 pharmacists were seeking a new product formulation to improve the appearance of skin and created Glycolic Acid skincare products. Acquired by the Pierre Fabre Group, the original Glytone formulations have been enhanced with the expertise of the Pierre Fabre company. Today, Glytone offers 8 different skincare systems Exclusive to Physicians that provide targeted solutions for skin health through the combination of in-office procedures and at-home treatments. THE GLYTONE DIFFERENCE PFAV (PRECISION FREE ACID VALUE) SYSTEM ydeterminates and discloses the strength and activity of Glycolic Acid for reliable and targeted treatment and maximal results, creating simply beautiful skin EXCLUSIVE TO PHYSICIANS ystrong effective products show rapid visible results ycomprehensive skincare systems adapted to the US market INNOVATIVE, PATENTED AND ADVANCED TECHNOLOGIES yprofessional Peel System with Enerpeel Technology ytime release delivery system yenhance Penetration Technology Glytone has been transforming skin for more than 20 years. With dazzling results from carefully crafted formulations, Glytone knows just what professionals and their patients need for beautiful, youthful skin. Whether it s in-office peel systems or home-care products to maintain dramatic results, we have created products for people who are serious about getting results. As a market pioneer in the use of Alpha Hydroxy Acids to refine the skin, Glytone provides the most comprehensive yet simple system for creating radiant, beautiful skin. Its broad range of products provides customizable solutions, no matter what your goals are. With a special focus on difficult to manage imperfections, including hyperpigmentation and photoaging, our products are highly effective while minimizing irritation. At Glytone, we have pioneered the validation of Glycolic Acids in our products. Skin experts know that many ingredients used in products can neutralize acids, making them less bioavailable to the skin, and therefore less effective. Often the strength listed on products doesn t represent what is bioavailable or the free acid value. With our validation process we call the PFAV System, we make sure you always get the strength we list on the package. Comprehensive skin care solutions that make sense and formulations that really work from the brand that knows how to transform skin. 2

3 Table of Contents PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness Glycolic Acid 30/50/70 Eye and Lip Back and Chest Remover Wipes Pyruvic Acid 50 Hand Mandelic Acid 40 Neck Jessner Preparatory Solution Wipes 4-11 TCA LP/Strong Salicylic Acid 30 Neutralizer Wipes REJUVENATING for Aging Skin and Peel Preparation/Maintenance Mild Gel Cleanser Rejuvenating Lotion 10/15/20 Rejuvenating Mini Peel Gel Rejuvenation System Normal to Dry Skin Mild Cream Cleanser Rejuvenating Cream 10/15/20 Gentle Rejuvenating Cream with Broad Spectrum Sunscreen SPF 15 Gentle Rejuvenating Lotion with Broad Spectrum Sunscreen SPF 15 Rejuvenating Mask Rejuvenation System Normal to Oily Skin AGE-DEFYING for Premature Skin Aging Age-Defying Vitamin C&E Serum Age-Defying Antioxidant Day Cream Age-Defying Antioxidant Eye Cream Age-Defying Antioxidant Night Cream BRIGHTENING for Hyperpigmented Skin Enhance Brightening Complex Dark Spot Corrector SunVanish Skin Lightening Cream Broad Spectrum SPF 25 Enhance Cleansing Toner Skin Lightening Cream Brightening System Lightening System Normal to Dry Skin Night Renewal Cream Skin Lightening Gel Lightening System Normal to Oily Skin ACNE THERAPY for Acne Acne Self-Foaming Cleanser Acne Treatment Lotion Acne Treatment Spray (Back and Chest) Acne Tinted Spot Treatment Acne Clearing Cleanser Acne 3P Treatment Gel Acne Treatment Mask Acne Clearing System Acne Clearing Toner BODY THERAPY for KP Dry, Rough Skin Exfoliating Body Wash Daily Body Lotion Broad Spectrum Sunscreen SPF 15 Ultra Softening Heel and Elbow Cream KP Kit Exfoliating Body Lotion RECOVERY for Post-Procedure Care and Hydration Soothing Lipid Recovery Cream Hydrating Cream Hydrating Lotion SUN PROTECTION for Daily UVA & UVB Protection Sunscreen Lotion Broad Spectrum SPF 40 3

4 PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness Glytone, the expert in Alpha Hydroxy Acids, provides reliable and predictable peel systems for discerning skin care professionals. Glytone has created an incredibly diverse line of peels. With special formulations for the face, back, hands, neck, chest (décolleté), and the delicate areas around the eyes and lips, we have designed systems and formulas for photodamaged skin, dark spots and acne-prone skin even for sensitive skin prone to redness. Our Professional Peel Systems with Enerpeel technology allows the peel solution to penetrate more homogenously through the skin layers, reducing surface trauma and minimizing irritation. They effectively penetrate skin for consistent, reliable exfoliation. This means longer lasting, visible results that patients will love. Predictability and visible results just what you would expect from Glytone. Glytone Professional Peel Systems incorporate a patented technology, Enerpeel, that delivers better results with less surface trauma. Glytone Professional Peel Systems are based on: ystrong acids (low pka) with low ph value (lower than simple aqueous solution of similar acids, and pka from 0.70 to 3.85) yincreased homogeneous absorption (patented carrier Dimethyl Isosorbide) ydecelerated proton mobility at the skin surface (lower value than simple aqueous solutions of similar acids) yminimization of inflammatory reaction (through Methyl-Sulfonyl-Methane (MSM)) fstrong f EFFICACY AND BETTER TOLERABILITY Peel Technology Enerpeel Technology The figure demonstrates the ability of Enerpeel Technology to improve the chemoexfoliant efficiency, decreasing the proportionality of irritation to renewal and overall increasing the remodelling of skin. 4 PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness

5 READ PROTOCOLS PRIOR TO USE AND FOLLOW PACKAGE DIRECTIONS Guide to Peel Perfection PROFESSIONAL PEEL SYSTEMS KEY INGREDIENTS RECOVERY TIME ADJUNCTIVE CARE Glycolic Acid 30/50/70 Aging / Premature Signs of Aging 30%, 50% and 70% Glycolic Acid None-Mild Rejuvenating Pyruvic Acid 50 Premature Signs of Aging / Acne-Prone Skin 50% Pyruvic Acid Mild-Moderate Age-Defying Acne Therapy Neck Premature Signs of Aging of Neck and Décolleté 30% Pyruvic Acid 10% Lactic Acid 0.5% Ferulic Acid Moderate Age-Defying Brightening TCA LP Chrono- & Photo-aging / Moderate Hyperpigmented Skin TCA Strong Chrono- & Photo-aging / Severe Hyperpigmented Skin 25% Trichloroacetic Acid Moderate 40% Trichloroacetic Acid Moderate Brightening Rejuvenating Age-Defying Eye and Lip Mild-Moderate Photo-aging of Eye / Lip Area 15% Lactic Acid 3.75% Trichloroacetic Acid Moderate Age-Defying Eye Cream Hand Mild-Moderate Photo-aging of Hands 20% Trichloroacetic Acid 10% Lactic Acid 0.5% Kojic Acid Moderate Brightening Jessner Premature Signs of Aging / Aging / Superficial Hyperpigmented Skin 20% Lactic Acid 15% Salicylic Acid 14% Resorcinol Mild Brightening Age-Defying Salicylic Acid 30 Acne-Prone Skin 30% Salicylic Acid None-Mild Acne Therapy Back and Chest Acne-Prone Skin on Back and Chest 30% Salicylic Acid None-Mild Acne Therapy Mandelic Acid 40 Skin Prone to Intermittent to Permanent Redness 40% Mandelic Acid None-Mild Rejuvenating PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness 5

6 READ PROTOCOLS PRIOR TO USE AND FOLLOW PACKAGE DIRECTIONS Professional Peel Systems Glycolic Acid 30/50/70 Professional Peel System Pyruvic Acid 50 Professional Peel System Neck SIZE System contains 1 informational CD and 15 of: Glycolic Acid 30 or 50 or 70 vials 2 ml / FL. OZ. each Prepatory Solution wipes Neutralizer wipes Brush Applicators INDICATION Mild to moderate signs of aging: fine lines and wrinkles, photodamage BENEFITS 30%/50%/70% Glycolic Acid Reduces visible signs of aging: fine lines, wrinkles, photodamage Improves skin texture and tone Increases hydration in stratum corneum Improves skin smoothness Strong efficacy with minimal surface trauma At Home Treatment: Glytone Rejuvenating system DIRECTIONS FOR USE After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayers. Leave on for 1 to 3 minutes depending on patient reaction. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to neutralization with Neutralizer Wipes Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure INGREDIENTS 30%: Water, Glycolic Acid, Dimethyl Sulfone, Dimethyl Isosorbide 50% & 70%: Glycolic Acid, Water, Dimethyl Sulfone, Dimethyl Isosorbide ADJUNCTIVE CARE Rejuvenating System contains 1 informational CD and 15 of: Pyruvic Acid 50 vials 2 ml / FL. OZ. each Prepatory Solution wipes Neutralizer wipes Brush Applicators Premature skin aging: Environmental damage, oxidative stress, aesthetic procedures Fine lines and wrinkles Acne-prone skin 50% Pyruvic Acid Decreases the appearance of fine lines, wrinkles and other premature signs of skin aging Reduces the appearance of acne-prone skin and pore size Improves the appearance of skin tone, texture, and smoothness Lessens the appearance of dark spots Strong efficacy with minimal surface trauma At Home Treatment: Glytone Age-Defying and Acne Therapy systems After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayers. Leave on for 1 to 5 minutes depending on patient reaction. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to neutralization with Neutralizer Wipes Patients should wait a minimum of 6 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure Pyruvic Acid, Dimethyl Isosorbide, Water, Dimethyl Sulfone, Ethyl Lactate, Propylene Glycol, Alcohol Denat. Age-Defying and Acne Therapy System contains 1 informational CD and 1 Neck Terminator Cream 1 Roller and 15 of: Neck vials 2 ml / FL. OZ. each Prepatory Solution wipes Neutralizer wipes Brush Applicators Aging skin on neck and décolleté Premature skin aging Chrono- & photo-aging Fine lines & wrinkles Uneven skin appearance in tone and texture Hyperpigmented skin around neck and décolleté 30% Pyruvic Acid + 10% Lactic Acid + 0.5% Ferulic Acid Decreases the appearance of fine lines and wrinkles Improves the appearance of dark spots around neck and décolleté Neck Terminator Cream helps to improve skin firmness, elasticity and even out skin appearance in tone and texture on neck and décolleté Ergonomic roller helps to improve absorption and homogeneous penetration of Neck Terminator Cream Helps to visibly decrease fine lines and wrinkles on neck and décolleté Strong efficacy with minimal surface trauma At Home Treatment: Glytone Age-Defying and Brightening systems After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayers. Leave on for 3 to 5 minutes depending on patient reaction. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to neutralization with Neutralizer Wipes. Patients should wait a minimum of 6 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure Neck Peel: Water, Pyruvic Acid, Lactic Acid, Alcohol Denat., Dimethyl Sulfone, Dimethyl Isosorbide, Ferulic Acid, Propylene Glycol Neck Terminator Cream: Water, Isononyl Isononanoate, C15-19 Alkane, Dimethyl Sulfone, Cyclopentasiloxane, Arachidyl Alcohol, Glycol Palmitate, Acetyl Glucosamine, Behenyl Alcohol, Glycerin, Cetearyl Alcohol, Ferulic Acid, Sodium Hyaluronate, Benzyl PCA, Arachidyl Glucoside, Acacia Senegal Gum, Cetearyl Glucoside, Xanthan Gum, Caprylyl Glycol, Caprylhydroxamic Acid, Pentaerythrytyl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Disodium EDTA, Propylene Glycol, Phenoxyethanol, Sodium Hydroxide. Age-Defying and Brightening 6 PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness

7 READ PROTOCOLS PRIOR TO USE AND FOLLOW PACKAGE DIRECTIONS Professional Peel Systems TCA LP/Strong Professional Peel System Eye and Lip Professional Peel System Hand SIZE System contains 1 informational CD and 15 of: TCA LP or TCA Strong vials 2 ml / FL. OZ. each Prepatory Solution wipes Neutralizer wipes Brush Applicators System contains 1 informational CD and: 4 Eye and Lip pens 2.5 ml / FL. OZ. each and 5 of: Prepatory Solution wipes Neutralizer wipes System contains 1 informational CD and 15 of: Hand vials 2 ml / FL. OZ. each Prepatory Solution wipes Neutralizer wipes Brush Applicators INDICATION Dark spots, sun spots, fine lines and wrinkles, small scars, and coarse wrinkles Chrono- & photo-aging around Eyes & Lips Moderate hyperpigmented skin around Eyes & Lips Moderate lines and wrinkles around Eyes & Lips Chrono- & photo-aging on hands Moderate hyperpigmented skin and moderate lines and wrinkles on the hands BENEFITS 25%/40% Trichloroacetic Acid Helps to decrease the appearance of moderate to severe hyperpigmented skin, fine lines and coarse wrinkles Formulated to minimize discomfort Strong efficacy with minimal surface trauma At Home Treatment: Glytone Brightening, Rejuvenating system and Age-Defying systems Lactic Acid 15% + Trichloroacetic Acid 3.75% Helps to visibly decrease chrono- and photoaging, dark spots and lines and wrinkles around eyes and lips Ergonomic pen, to ease the application around eyes and lips Gel formula with standardized delivery system Strong efficacy with minimal surface trauma At Home Treatment: Glytone Brightening and Age-Defying systems Reduces the appearance of dark spots Improves the appearance of fine lines, small scars and coarse wrinkles on the hands Gives immediate skin brightening effect Improves skin tone and texture Strong efficacy with minimal surface trauma At Home Treatment: Glytone Brightening system DIRECTIONS FOR USE After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayer. Leave on for 1-4 minutes; neutralize 5-8 seconds after the appearance of an homogenous frosting. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to neutralization with Neutralizer Wipes Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayer. Leave on for up to 3 minutes per layer, 5 minutes for the 4 th (final) layer. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to neutralization with Neutralizer Wipes Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayers. Leave on for 1-2 minutes per layer. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to neutralization with Neutralizer Wipes Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure INGREDIENTS Water, Trichloroacetic Acid, Dimethyl Sulfone, Dimethyl Isosorbide, Propylene Glycol Water, Lactic Acid, Alcohol Denat., Dimethyl Sulfone, Dimethyl Isosorbide, Trichloroacetic Acid, Citric Acid, Propylene Glycol, Xanthan Gum Water, Trichloroacetic Acid, Lactic Acid, Dimethyl Sulfone, Alcohol Denat., Dimethyl Isosorbide, Propylene Glycol, Kojic Acid ADJUNCTIVE CARE Brightening, Rejuvenating and Age-Defying Brightening and Age-Defying Brightening PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness 7

8 READ PROTOCOLS PRIOR TO USE AND FOLLOW PACKAGE DIRECTIONS Professional Peel System Jessner Professional Peel System Salicylic Acid 30 Professional Peel System Back and Chest SIZE System contains 1 informational CD and 15 of: Jessner vials 2 ml / FL. OZ. each Prepatory Solution wipes Remover wipes Brush Applicators System contains 1 informational CD and 15 of: Salicylic Acid 30 vials 2 ml / FL. OZ. each Prepatory Solution wipes Remover wipes Brush Applicators System contains 1 informational CD, Roller, and 8 of: Back and Chest Spray Bottles 5 ml / FL. OZ. each Prepatory Solution wipes Remover wipes INDICATION Dark spots, sun spots, chrono-photo aging, fine lines and wrinkles Acne-prone skin Oily, acne-prone skin on the back and chest BENEFITS 20% Lactic Acid + 15% Salicylic Acid + 14% Resorcinol Helps to visibly reduce signs of premature skin aging, chrono- and photo-aging, moderate hyperpigmented skin, and sun spots Helps to decrease fine lines and wrinkles Strong efficacy with minimal surface trauma At Home Treatment: Glytone Brightening and Age-Defying systems 30% Salicylic Acid Helps to reduce the appearance of oily, acne-prone skin Helps to decrease excess sebum Improves complexion brightness Improves overall appearance of skin Strong efficacy with minimal surface trauma At Home Treatment: Glytone Acne Therapy system 30% Salicylic Acid Helps to reduce the appearance of oily, acne-prone skin Helps to decrease excess sebum Improves complexion brightness Improves overall appearance of skin Strong efficacy with minimal surface trauma At Home Treatment: Glytone Acne Therapy system DIRECTIONS FOR USE After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayer. Leave on for 2 to 3 minutes per layer depending on patient reaction. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to removal with Remover Wipes Note: A white precipitate of Salicylic Acid due to the evaporation of the solution can be observed after 1-2 minutes and should not be confused with frosting. The application of further layers of solution (generally 4-6) can lead to the formation of actual frosting Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure INGREDIENTS Alcohol Denat., Lactic Acid, Salicylic Acid, Resorcinol, Dimethyl Isosorbide, Dimethyl Sulfone, PEG-14 Dimethicone, Propylene Glycol ADJUNCTIVE CARE Brightening and Age-Defying After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayers. Leave on for 3 to 5 minutes depending on patient reaction. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to removal with Remover Wipes Note: from 1 minute of application, a white precipitate of salicylic acid should appear due to evaporation of the solution. This should not be confused with frosting Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure Alcohol Denat., Salicylic Acid, Triethyl Citrate, Water, Oligopeptide-10, Ethyl Linoleate, Dimethyl Isosorbide, Propylene Glycol, Hexylene Glycol, Butylene Glycol, Caprylyl Glycol, Phenoxyethanol, Potassium Sorbate Acne Therapy After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the spray 7 to 10 inches (20 to 25 cm) from the skin. Peel solution can be applied in multilayers. Use Roller for a more uniform distribution of the solution. Leave on for 3 to 5 minutes depending on patient reaction. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to removal with Remover Wipes Note: from 1 minute of application, a white precipitate of salicylic acid should appear due to evaporation of the solution. This should not be confused with frosting Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure The roller can be cleansed with any regular disinfectant solution (chlorhexidine, benzalkonium chloride, ethyl alcohol) after use Alcohol Denat., Salicylic Acid, Triethyl Citrate, Water, Ethyl Linoleate, Dimethyl Isosorbide, Pentylene Glycol, Oligopeptide-10, Butylene Glycol, Phenoxyethanol, Caprylyl Glycol, Potassium Sorbate, Hexylene Glycol Acne Therapy 8 PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness

9 READ PROTOCOLS PRIOR TO USE AND FOLLOW PACKAGE DIRECTIONS Professional Peel System Mandelic Acid 40 Preparatory Solution Wipes Neutralizer Wipes Remover Wipes SIZE System contains 1 informational CD and 15 of: Professional Peel System Mandelic Acid 40 vials 2 ml / FL. OZ. each Prepatory Solution wipes Neutralizer wipes Brush Applicators 15 Single-use preparatory solution wipes 3 ml / 0.1 FL. OZ. each 15 Single-use neutralizer wipes 3 ml / 0.1 FL. OZ. each 15 Single-use remover wipes 3 ml / 0.1 FL. OZ. each INDICATION Skin characterized by intermittent and permanent redness Prepares skin for chemoexfoliation procedures targeting: Premature skin-aging Chrono- & Photo-aging Dark spots Fine lines & wrinkles Uneven skin appearance in tone and texture Clogged pores Surface oils For use immediately after Glycolic Acid 30, 50, 70; Mandelic Acid 40; Pyruvic Acid 50; TCA LP; TCA STRONG, Eye and Lip, Hand, and Neck peels to neutralize peel effect on the skin For use immediately after Salicylic Acid 30; Back and Chest; and Jessner peels to neutralize peel effect on the skin BENEFITS 40% Mandelic Acid Helps to visibly reduce skin redness Minimizes mild chrono- or photo-aging and mild hyperpigmented skin Improves skin color, texture and pore size Strong efficacy with minimal surface trauma At Home Treatment: Glytone Rejuvenating system Single-use preparatory wipe to delipidify and prime the skin before chemoexfoliation procedures Single-use neutralizer wipe immediately stops peeling action and brings ph to a nonaggressive level Single-use remover wipe immediately stops peeling action and brings ph to a nonaggressive level DIRECTIONS FOR USE After skin is cleansed and primed with Preparatory Solution Wipes, apply the peel solution using the brush applicator. Peel solution can be applied in multilayers. Leave on for 2 to 10 minutes, based on patient reaction. Frequently assess the patient s discomfort and constantly monitor for redness, pain and undesired frosting of the skin. Patient s discomfort should be assessed using a verbal scale from 1 to 10, with 10 being the most hot and painful. If you observe undesired frosting, increasing redness or a discomfort level of 6 or higher, discontinue application and proceed to neutralization with Neutralizer Wipes Patients should wait a minimum of 2 hours before contact with water and avoid strenuous exercise on the day of the procedure Apply a thin layer of a skin recovery cream (Glytone Soothing Lipid Recovery Cream) after neutralization. Application should continue for 3-5 days following the chemical peel. Use a sunscreen (Glytone Sunscreen Lotion Broad Spectrum SPF 40) for 7 days after the procedure Prior to peel, open Preparatory Solution Wipes so it is ready to use. Prepare eye pads and nasal plugs or equivalent for protection of eyes and nasal passage. Apply on face, avoiding the eye contour, to remove excess oil and prepare the skin for a chemical peel. This product does not need to be rinsed before peel application Prior to peel, open Neutralizer Wipes wipe so it is ready to use. Prepare eye pads and nasal plugs or equivalent for protection of eyes and nasal passage. After determined application time has elapsed, neutralize with Neutralizer Wipes Prior to peel, open Remover Wipes so it is ready to use. Prepare eye pads and nasal plugs or equivalent for protection of eyes and nasal passage. After determined application time has elapsed, remove with Remover Wipes INGREDIENTS Mandelic Acid, Water, Alcohol Denat., Dimethyl Sulfone, Dimethyl Isosorbide, Propylene Glycol, PEG-14 Dimethicone Alcohol Denat., Acetone, Dimethyl Isosorbide Water, Arginine, Dimethyl Isosorbide, Propylene Glycol, Disodium EDTA, Phenoxyethanol, Methylparaben, Ethylparaben, Propylparaben Dicaprylyl Ether, Isononyl Isononanoate ADJUNCTIVE CARE Rejuvenating PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness 9

10 READ PROTOCOLS PRIOR TO USE AND FOLLOW PACKAGE DIRECTIONS Professional Peel Systems: Before & After Glycolic Acid 30/50/70 For Aging / Premature Signs of Aging BEFORE After picture taken after 4 procedures. Photographs courtesy of Prof. Dr. Berardesca AFTER 4 PEELS Pyruvic Acid 50 For Premature Signs of Aging / Acne-Prone Skin BEFORE After picture taken after 1 procedure. Photo courtesy of Dr. Sylwia Lipko-Godlewska. AFTER 1 PEEL (DOUBLE LAYER) Neck For Premature Signs of Aging of Neck and Décolleté BEFORE After picture taken after 4 procedures. Photo courtesy of Dr. Maria Gabriella Di Russo AFTER 4 PEELS AND NECK TERMINATOR CREAM TCA LP/Strong For Chrono- & Photo- Aging / Moderate and Severe Hyperpigmented Skin BEFORE After picture taken 2 weeks after the procedure. Photo courtesy of Dr. Ivona Percec AFTER 1 PEEL (SINGLE LAYER) Eye and Lip For Mild-Moderate Photo-aging of Eye / Lip Area BEFORE AFTER 4 PEELS (SINGLE LAYER) BEFORE After picture taken 7 days post procedure. Photographs courtesy of Dr. Sylwia Lipka-Godlewska AFTER 4 PEELS (SINGLE LAYER) 10 PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness

11 READ PROTOCOLS PRIOR TO USE AND FOLLOW PACKAGE DIRECTIONS Hands For Mild-Moderate Photo-aging of Hands BEFORE After picture taken 2 weeks post procedure. Photographs courtesy of Dr. Ivona Percec AFTER 1 PEEL (DOUBLE LAYER) Jessner For Premature Signs of Aging / Aging / Superficial Hyperpigmented Skin After picture taken after 3 procedures. BEFORE AFTER 3 PEELS (DOUBLE LAYER) Salicylic Acid 30 For Acne-Prone Skin BEFORE AFTER 4 PEELS After picture taken after 4 procedures. Photographs courtesy of Prof. Giuseppe Micali in collaboration with Dr. Aurora Tedeschi Back and Chest For Acne-Prone Skin on Back and Chest BEFORE AFTER 4 PEELS (DOUBLE LAYER) After picture taken 2 weeks post procedure. Photographs courtesy of Dr. Enzo Berardesca in collaboration with Dr. Jo Linda Sinagra Mandelic Acid 40 For Skin Prone to Intermittent to Permanent Redness BEFORE After picture taken 2 weeks post procedure. Photographs courtesy of Dr. Ivona Percec AFTER 1 PEEL (SINGLE LAYER) PROFESSIONAL PEEL SYSTEMS for Aging, Hyperpigmented, Acne-Prone Skin and Redness 11

12 REJUVENATING for Aging Skin and Peel Preparation / Maintenance The Glytone Rejuvenating line, featuring the PFAV * system, offers comprehensive regimens that quickly and reliably exfoliate and retexturize the skin. PFAV * system shows an amount of bioavailable Glycolic Acid in a product, called Free Acid Value. Rejuvenating products help your patients step up through the process of increasing the levels of available acid to the skin. With the PFAV * system, these products will help your patients maximize the results with less irritation creating simply beautiful skin. Recommend the Rejuvenating regimens as daily care to visibly reduce signs of aging, such as fine lines and wrinkles, or as the primer to optimize and elevate aesthetic procedures, such as peels and laser treatments. Enhance your artistry with Glytone. Rejuvenating line offers: yoptimized bioavailability to obtain Free Acid Value benefits Non-neutralized solution of glycolic acid combined with a lower, controlled ph Delivers more free glycolic acid to the skin to achieve a higher efficacy Glytone Products yactive Technology Free Acid Value Mild Gel Cleanser 4.7 Mild Cream Cleanser 3.4 Rejuvenating Cream 10, 15, 20 10, 15, 20 Rejuvenating Lotion 10, 15, 20 10, 15, 20 Rejuvenating Mini Peel Gel 10.8 Dermal effects of free glycolic acid levels 0 Free Acid Values and Their Effects (1) 20 Reversal in basal cell atypia Significant increase in collagen deposition 8-12 Significant increase in cellular turnover 4-8 Moderate increase in cellular turnover 2-4 Smoother softer skin 0-2 Increased moisturization 5 10 Free Acid Value Multiple bilayers allow the release of inner core contents Large cargo hold permits prolonged release of moisture and glycolic acid A patented Novasome Microvesicle delivery system provides immediate and prolonged release of skin rejuvenating Glycolic Acid for visible results with less irritation * Precision Free Acid Value (1) Barone, Pat. How to Deliver Good Glycolic Acid Therapy, Dermatol Times, Jan REJUVENATING for Aging Skin and Peel Preparation / Maintenance

13 Mild Cleansers Rejuvenate skin and reveal healthy looking complexion Facial cleansing is an extremely important part of any skin care regimen: yremoves build up (oil, dirt, unwanted debris) for better penetration of other products yboosts hydration for revitalized complexion ymaintains clean skin for a soft and smooth appearance Mild Gel Cleanser Mild Cream Cleanser SIZE 200 ml / 6.7 FL. OZ. 200 ml / 6.7 FL. OZ. INDICATION For normal to oily skin to visibly reduce skin aging effects: Fine lines and wrinkles Uneven skin appearance in tone and texture Photodamaged skin For normal to dry skin to visibly reduce skin aging effects: Fine lines and wrinkles Uneven skin appearance in tone and texture Photodamaged skin BENEFITS Glycolic Acid (4.7 PFAV *) exfoliates dead skin cells and moisturizes skin 3.5 ph value Use as part of anti-aging skincare regimen Prepares the skin and enhances results from chemical peels A rich, lathering formula that thoroughly cleanses and leaves skin feeling soft, smooth and clean Oil-free Glycolic Acid (3.4 PFAV *) exfoliates and moisturizes skin 3.5 ph value Use as part of anti-aging skincare regimen Prepares the skin and enhance results from chemical peels A rich, lathering formula that thoroughly cleanses and leaves skin feeling soft, smooth and clean DIRECTIONS TO USE Use twice daily or as directed by your physician. Dispense a small amount into your hand and mix with a little water. Massage over wet face and neck in circular motion. Rinse thoroughly with warm water and pat dry. Use twice daily or as directed by your physician. Dispense a small amount into your hand and mix with a little water. Massage over wet face and neck in circular motion. Rinse thoroughly with warm water and pat dry. INGREDIENTS Water, Cocamidopropyl Betaine, Glycerin, Glycolic Acid, Potassium Hydroxide, Sodium Lauryl Sulfate, TEA-Dodecylbenzenesulfonate, Blue 1, Green 3. Water, Glycerin, Cocamidopropyl Betaine, Magnesium Aluminum Silicate, Glycolic Acid, Lauramine Oxide, PEG-40 Stearate, Cetearyl Alcohol, Octoxynol-5, Octoxynol-9, Petrolatum, Potassium Hydroxide, Citrus Aurantium Dulcis (Orange) Oil, Hydroxyethylcellulose, Methylparaben, Polysorbate 20, Propylparaben, Stearic Acid, Red 40, Yellow 5. * Precision Free Acid Value REJUVENATING for Aging Skin and Peel Preparation / Maintenance 13

14 Rejuvenating Cream 10/15/20 Rejuvenating Lotion 10/15/20 Gentle Rejuvenating Cream with Broad Spectrum Sunscreen SPF 15 Gentle Rejuvenating Lotion with Broad Spectrum Sunscreen SPF 15 SIZE NET WT. 50 g / 1.7 OZ. 60 ml / 2 FL. OZ. NET WT. 50 g / 1.7 OZ. 60 ml / 2 FL. OZ. INDICATION For normal to dry aging skin: Fine lines and wrinkles Uneven skin appearance in tone and texture Photodamaged skin For normal to oily aging skin: Fine lines and wrinkles Uneven skin appearance in tone and texture Photodamaged skin For normal to dry delicate aging skin: First time AHA users Delicate skin Fine lines and wrinkles Uneven skin appearance in tone and texture For normal to oily delicate aging skin: First time AHA users Delicate skin Fine lines and wrinkles Uneven skin appearance in tone and texture BENEFITS Available in three increasing concentrations, highly effective Glycolic Acid (PFAV *) exfoliates dead surface cells and moisturizes to help reveal younger looking skin: 10 PFAV * 15 PFAV * 20 PFAV * 3.0 ph value Reduces the appearance of fine lines, wrinkles, photodamage and other signs of aging Prepares for and maintains the benefits of in-office chemical peels Enhances skin tone and smoothness for a healthy looking revitalized complexion Available in three increasing concentrations, highly effective Glycolic Acid (PFAV *) exfoliates dead surface cells and moisturizes to help reveal younger looking skin: 10 PFAV * 15 PFAV * 20 PFAV * 3.0 ph value Reduces the appearance of fine lines, wrinkles, photodamage and other signs of aging Prepares for and maintains the benefits of in-office chemical peels Enhances skin tone and smoothness for a healthy looking revitalized complexion Utilizes the breakthrough combination of time-released Glycolic Acid Complex for a healthy looking, revitalized complexion Sun protecting agents (2% Avobenzone, 6% Octinoxate) protects against UV damage Collagen and Hyaluronic Acid visibly plump and firm the skin for brighter, younger looking skin Hydrolyzed Collagen and Avocado Oil provide added moisturizing benefits PABA-free Utilizes the breakthrough combination of time-released Glycolic Acid Complex for a healthy looking, revitalized complexion Sun protecting agents (2% Avobenzone, 7% Octinoxate) protects against UV damage Collagen and Hyaluronic Acid visibly plump and firm the skin for brighter, younger looking skin Hydrolyzed Collagen and Avocado Oil provide added moisturizing benefits PABA-free DIRECTIONS FOR USE Apply daily to cleansed face and neck or as directed by your physician. Shake well before use. Apply daily to cleansed face and neck or as directed by your physician. Apply Gentle Rejuvenating Cream in the morning to cleansed face and neck or as directed by a doctor at least 15 minutes before sun exposure. At least every 2 hours apply a sunscreen with broad spectrum SPF 15 or higher for sun protection. Use a water resistant sunscreen if swimming or sweating. Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m.-2 p.m.; wear long-sleeve shirts, pants, hats and sunglasses Apply Gentle Rejuvenating Lotion in the morning to cleansed face and neck or as directed by a doctor at least 15 minutes before sun exposure. At least every 2 hours apply a sunscreen with broad spectrum SPF 15 or higher for sun protection. Use a water resistant sunscreen if swimming or sweating. Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF of 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m.-2 p.m.; wear long-sleeve shirts, pants, hats and sunglasses. INGREDIENTS Water, Glycolic Acid, Dimethicone, Cetearyl Glucoside, Trisiloxane, Sodium Hydroxide, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Isostearyl Palmitate, Ceteth-10, Glyceryl Stearate SE, Magnesium Aluminum Silicate, Glycerin, Bis-Hydroxyethoxypropyl Dimethicone, Silica, Laureth-4, Polysorbate 20, Polyacrylamide, Titanium Dioxide, C13-C14 Isoparaffin, Cetyl Hydroxyethylcellulose, Methylparaben, Propylparaben, Propylene Glycol, Laureth-7, Sodium Polyacrylate, Styrene/Acrylates Copolymer, Hydrolyzed Corn Starch, Ammonium Hydroxide, Tocopherol, PVM/MA Copolymer. * Precision Free Acid Value Water, Glycolic Acid, Ceteareth-6 Olivate, PEG-6 Caprylic/Capric Glycerides, Isododecane, Dimethicone, Glycerin, Silica, Sodium Hydroxide, Polysorbate 20, Microcrystalline Cellulose, Polysilicone-11, Citric Acid, Stearyl Alcohol, Ceteareth-20, Hydroxyethylcellulose, Hydrolyzed Corn Starch, Cellulose Gum, Propylene Glycol, Imidazolidinyl Urea, Methylparaben, Propylparaben. Active Ingredients: Avobenzone 2 %, Octinoxate 6 % Inactive Ingredients: Water, Glycolic Acid, Cyclomethicone, Ammonium Hydroxide, Butyloctyl Salicylate, Glyceryl Stearate, Butylene Glycol, Ethylhexyl Palmitate, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, PEG-150 Stearate, Hydrogenated Avocado Oil, Cetyl Alcohol, Dimethiconol, Glycine Soja (Soybean) Sterols, Butyrospermum Parkii (Shea Butter), Petrolatum, Silica, Phenoxyethanol, Dicetyl Phosphate, Methylparaben, Cetearyl Glucoside, Ceteth-10 Phosphate, Glycerin, Tocopheryl Acetate, Disodium EDTA, Xanthan Gum, Hydrolyzed Collagen, Hyaluronic Acid. Active Ingredients: Avobenzone 2 %, Octinoxate 7 % Inactive Ingredients: Water, Glycolic Acid, Cyclomethicone, Butyloctyl Salicylate, Glyceryl Stearate, Glycerin, Stearoxy Dimethicone, Ammonium Hydroxide, PEG-150 Stearate, Cetyl Alcohol, Dimethiconol, Glycine Soja (Soybean) Sterols, Phenoxyethanol, Xanthan Gum, Methylparaben, Polyacrylamide, Tocopheryl Acetate, Disodium EDTA, C13-14 Isoparaffin, Laureth REJUVENATING for Aging Skin and Peel Preparation / Maintenance

15 Rejuvenating Systems NORMAL TO OILY/DRY SKIN SIZE Rejuvenating Mini Peel Gel Rejuvenating Mask 60 ml / 2 FL. OZ. NET WT. 85 g / 3 OZ. INDICATION For delicate aging skin: First time AHA users Delicate skin Fine lines and wrinkles Uneven skin appearance in tone and texture For delicate aging skin: First time AHA users Delicate skin Fine lines and wrinkles Uneven skin appearance in tone and texture Transform the skin with the PFAV * system, which determines and discloses activity of Glycolic Acid in the products to allow for targeted and individualized treatments for a better outcome and patient experience Complete daily regimen with Glytone hero products Improve skin texture and tone Visibly reduce imperfections and signs of aging BENEFITS Contains highly effective exfoliant, Glycolic Acid (10.8 PFAV *), to retexturize and rejuvenate the skin and help reduce the appearance of fine lines and wrinkles for a smoother, younger looking complexion 3.3 ph value Utilizes a gel texture for a better absorption of the ingredients Delivers enhanced exfoliation athome and maintains improvements in skin tone and texture between and after in-office exfoliation procedures Oil-free DIRECTIONS FOR USE Apply a thin layer to cleansed face and neck. Leave on for 10 minutes and rinse with warm water. Pat skin dry. Apply two to three times per week or as directed by your physician. Contains a potent mix of Lactic, Ascorbic (Vitamin C) and Glycolic Acids (3.0 PFAV *) to revitalize, cleanse pores and reduce the appearance of fine lines and wrinkles Collagen hydrates Vitamin C provides antioxidant and skin brightening benefits Purges clogged pores and absorbs excess oils for even complexion Boost any at-home regimen by keeping the skin clear Oil-free Apply a generous layer over entire face and neck one to three times per week, or as directed by your physician. Leave on minutes. Remove with lukewarm water and pat dry Rejuvenate 4 Cleanse Mild Gel/Cream Cleanser Rejuvenate and Protect Gentle Rejuvenating Lotion/Cream with Broad Spectrum Sunscreen SPF 15 and Exfoliate Rejuvenating Lotion/Cream 10 Exfoliate and Enhance Rejuvenating Mini Peel Gel INGREDIENTS Water, SD Alcohol 40-A, Glycolic Acid, Propylene Glycol, Hydroxypropylcellulose, Potassium Hydroxide, BHT. Water, Kaolin, Bentonite, Zinc Oxide, Glycolic Acid, Isopropyl Alcohol, Glycerin, Soluble Collagen, Lactic Acid, Ascorbic Acid, BHT, Disodium EDTA, Menthol, Methylparaben, Propyl Gallate, Sodium Lauryl Sulfate. * Precision Free Acid Value REJUVENATING for Aging Skin and Peel Preparation / Maintenance 15

16 AGE-DEFYING for Premature Skin Aging No-matter what condition the skin is in, age prevention is key. Help protect your patients investment and skin health with the daily use of Glytone Age-Defying products. Packed with highly effective antioxidants and skin-loving peptides, these products will nurture and defend your patients skin, keeping it in tip-top shape. Glytone Age-Defying line works to visibly erase the signs of chrono- and photo-aging while protecting skin from environmental stress. Your secret weapon for keeping patients looking and feeling great. Synergistic Combination yantioxidants Antioxidants serve as one of the most powerful and potent anti-aging ingredients, helping to protect the skin from damage caused by free radicals. yglycolic Acid (Free Acid Value) Glycolic Acid (3-in-1 multitasking ingredient) is one of the most effective ingredient to fight signs of aging skin. It exfoliates, moisturizes and enhances penetration of other ingredients into the skin. y Peptides Peptides support natural skin repair, reinforce skin defense and reduce the appearance of lines and wrinkles. 16 AGE-DEFYING for Premature Skin Aging

17 Age-Defying Vitamin C+E Serum Your daily secret weapon for keeping fabulous looking skin Key Advanced Ingredients THD Ascorbate yhigh concentration, stable Vitamin C ytime-released yprotects against cell damage caused by free radicals Delta-Tocopheryl Glucoside yphysiological precursor of Vitamin E yphotostable Vitamin E with reservoir effect ynourishes the skin Red Tea Flavonoids yminimize free radical damage of the skin SIZE 30 ml / 1 FL. OZ. INDICATION Premature Aging skin caused by environmental damage Oxidative stress Post-Aesthetic procedures such as IPL and microdermabrasion BENEFITS High concentrations of time-released Vitamin C (Tetrahexyldecyl Ascorbate) and Vitamin E (Delta Tocopheryl Glucoside) combined with Red Tea Flavonoids provide an antioxidative protective layer to help prevent free radical damage Ideal in post-aesthetic procedures as certain procedures temporarily increase free radical oxidation (such as IPL, microdermabrasion) DIRECTIONS FOR USE Once in the morning after cleansing, apply to dry face, neck and décolleté. For enhanced results, follow with Glytone Age-Defying Antioxidant Day Cream. INGREDIENTS Water, Tetrahexyldecyl Ascorbate, Tocopheryl Glucoside, Sodium Palmitoyl Proline, Nymphaea Alba Flower Extract, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 60, Hydroxypropyltrimonium Maltodextrin Crosspolymer, Cucumis Melo (Melon) Fruit Extract, Aspalathus Linearis Leaf (Red Tea) Extract, Glycerin, 1,2-Hexanediol, Caprylyl Glycol, Tropolone. AGE-DEFYING for Premature Skin Aging 17

18 Age-Defying Antioxidant Day Cream Age-Defying Antioxidant Eye Cream Age-Defying Antioxidant Night Cream SIZE 50 ml / 1.7 FL. OZ. 15 ml / 0.5 FL. OZ. 30 ml / 1 FL. OZ. INDICATION Premature Aging skin caused by environmental damage Oxidative stress Aesthetic procedure such as IPL and microdermabrasion Premature Aging skin caused by environmental damage Oxidative stress Aesthetic procedure such as IPL and microdermabrasion Premature Aging skin caused by environmental damage Oxidative stress Aesthetic procedure such as IPL and microdermabrasion BENEFITS Time-released Vitamin E (Delta-Tocopheryl Glucoside complex) and Red Tea Flavonoids (Antioxidants) reinforce antioxidative action while triggering exfoliation through the use of Glycolic Acid (5.5 PFAV *), helping to reduce the visible signs of aging Hyaluronic Acid hydrates and plumps the skin This product helps in post-aesthetic procedures as certain procedures temporarily increase free radical oxidation (such as IPL, microdermabrasion) Oil-free Red Tea Flavonoids help to protect eye area from free radical damage Caffeine and Licorice extract help to lessen the appearance of dark circles, de-puff, brighten and tighten the skin Antioxidant Duo: Red Tea Flavonoids and timereleased Vitamin E (Delta-Tocopheryl Glucoside) protect skin from free radical damage and prevents premature aging Unique Peptide Complex (Caprooyl Tetrapeptide-3 and Acetyl Tetrapeptide-2) makes the skin look firm, toned and smooth Glycolic Acid (5.5 PFAV )* exfoliates and moisturizes skin for renewed complexion Oil-free DIRECTIONS FOR USE Use once in the morning after applying Glytone Age-Defying Vitamin C+E Serum. Apply a thin layer to entire face or as directed by your physician. Pat a small amount under eye area and over brow bone until fully absorbed. Use morning and night. In the evening, apply a thin layer to entire face, neck and décolleté or as directed by your physician. INGREDIENTS Water, Glycolic Acid, Isodecyl Neopentanoate, Isononyl Isononanoate, Sodium Hydroxide, Xylitylglucoside, Arachidyl Alcohol, Dipalmitoyl Hydroxyproline, Tocopheryl Glucoside, Dimethicone, Anhydroxylitol, Xylitol, Behenyl Alcohol, Arachidyl Glucoside, Cetearyl Alcohol, Hyaluronic Acid, 1,2-Hexanediol, Caprylyl Glycol, Tropolone, Polyacrylate-13, Polyisobutene, Polysorbate 20, Xanthan Gum, Hydroxypropyltrimonium Maltodextrin Crosspolymer, Cucumis Melo (Melon) Fruit Extract, Aspalathus Linearis Leaf (Red Tea) Extract. Water, Isodecyl Neopentanoate, Isononyl Isononanoate, Dipentaerythrityl Pentaisononanoate, Xylitylglucoside, Glycol Palmitate, Anhydroxylitol, Polyacrylate-13, Arachidyl Alcohol, Xylitol, Polyisobutene, Polysorbate 20, Behenyl Alcohol, Arachidyl Glucoside, Sodium Palmitoyl Proline, Nymphaea Alba Flower Extract, Cetearyl Alcohol, Coco-Glucoside, 1,2-Hexanediol, Caprylyl Glycol, Tropolone, Dipalmitoyl Hydroxyproline, Dimethicone, Caffeine, Butylene Glycol, Chenopodium Quinoa Seed Extract, Aspalathus Linearis Leaf (Red Tea) Extract, Glycerin, Glycyrrhiza (Licorice) Root Extract, Glycolic Acid, Triethanolamine. Water, Glycolic Acid, Butyrospermum Parkii (Shea Butter), Arachidyl Alcohol, Cetearyl Alcohol, Isononyl Isononanoate, Isodecyl Neopentanoate, Sodium Hydroxide, Xylitylglucoside, Behenyl Alcohol, Polyacrylate-13, Glycerin, PEG-100 Stearate, Glyceryl Stearate, Dipentaerythrityl Pentaisononoate, Tocopheryl Glucoside, Dimethicone, Phenoxyethanol, Anhydroxylitol, Arachidyl Glucoside, Polyisobutene, Xylitol, Butylene Glycol, Ethylhexylglycerin, Disodium EDTA, Aspalathus Linearis Leaf (Red Tea) Extract, Polysorbate 20, Glucose, Dextran, Caprooyl Tetrapeptide-3, Acetyl Tetrapeptide-2. * Precision Free Acid Value 18 AGE-DEFYING for Premature Skin Aging

19 Innovative Exclusive Combination Antioxidants yvitamin C - THD Ascorbate for better tolerability Protects against cell damage caused by free radicals yvitamin E - Delta-Tocopheryl Glucoside Nourishes the skin yred Tea Flavonoids Minimizes free radical damage of the skin Peptides ychronoline - Caprooyl Tetrapeptide-3 Reduces the appearance of fine lines and wrinkles ythymulen -4 - Acetyl Tetrapeptide-2 Provides a powerful barrier against external factors for a youthful appearance of skin Glycolic Acid - Free Acid Value Moisturizes, exfoliates and enhances penetration of other ingredients into the skin 1 Prevent Age-Defying Vitamin C+E Serum 2 Improve Age-Defying Antioxidant Day Cream 3Improve Age-Defying Antioxidant Eye Cream 4 Renew Age-Defying Antioxidant Night Cream AGE-DEFYING for Premature Skin Aging 19

20 BRIGHTENING for Hyperpigmented Skin Pigmentary lesions, even though mostly asymptomatic, have an important impact on a patient s quality of life. (1) Hyperpigmentation is the 2 nd most common skincare concern in the professional channel. (2) Unwanted pigmentation is caused by multiple factors like overexposure to the sun, heredity, hormonal changes, medications, and inflammation. This is why Glytone has created the perfect combination of products to attack the problem on multiple fronts. Glytone Brightening line is an effective at-home system to brighten the skin for a glowing and radiant complexion. Glytone prescription-strength 4 % hydroquinone products are available by prescription only. SEE THE DIFFERENCE BEFORE AFTER (3) (1) Pigmentation disorders: hyperpigmentation and hypopigmentation. Nicolaidou E1, Katsambas AD, (2) Professional Skin Care: U.S. Market Analysis and Opportunities. Kline report, (3) Clinical efficacy study in 33 women for 16 weeks. T. NOCERA, C. COUTANCEAU, V. DUROSIER. 20 BRIGHTENING for Hyperpigmented Skin

21 Enhance Brightening Complex Brightens your skin for a more even, radiant complexion 84% of patients reported visible results in 8 weeks* 62% reduction in the appearance of dark spots* Results continue to improve with regular use* SIZE Visible results as early as 8 weeks* 30 ml / 1 FL. OZ. INDICATION For hyperpigmented skin: Unwanted dark spots Uneven skin tone and texture NEW! BENEFITS Brighten your skin for a more even, radiant tone: Azelaic Acid brightens skin s appearance Glycolic Acid exfoliates dead skin cells from skin surface and increase penetration on Azelaic Acid into the skin Visibly improve the appearance of unwanted dark spots and uneven skin tone and texture Leaves the skin soft and hydrated Fragrance free Paraben free Hypoallergenic DIRECTIONS FOR USE Apply morning and evening to cleansed affected areas (face and décolleté). For optimal results, use for 3 months with a broad spectrum sunscreen during the day. INGREDIENTS Water, Azelaic Acid, Caprylic/Capric Triglyceride, Dicaprylyl Ether, Cetearyl Alcohol, Cyclopentasiloxane, Glycolic Acid, Cyclohexasiloxane, Glyceryl Stearate, Ceteareth-33, Sodium Hydroxide, Acetic Acid, Benzoic Acid, Disodium EDTA, Sodium Chloride, Tocopherol. * Clinical efficacy study in 33 women for 16 weeks. T. NOCERA, C. COUTANCEAU, V. DUROSIER. BRIGHTENING for Hyperpigmented Skin 21

22 Enhance Cleansing Toner Night Renewal Cream Dark Spot Corrector SIZE 200 ml / 6.7 FL. OZ. 50 ml / 1.6 FL. OZ. 60 ml / 2 FL. OZ. INDICATION Hyperpigmented skin/uneven skin tone Sun spots Fine lines & wrinkles Hyperpigmented skin/uneven skin tone Sun spots Fine lines & wrinkles Dark (brownish) discolorations in the skin such as: freckles, age and liver spots or pigment in the skin that may occur in pregnancy or from the use of oral contraceptives. BENEFITS Salicylic Acid to exfoliates and helps remove dead surface skin cells Restores the skin s natural ph Prepares the skin for treatment Gently cleanses and tightens pores Lightweight and refreshing Oil-free Glycolic Acid (5.5 PFAV *) and Retinaldehyde to help smooth and firm skin, revealing younger, healthier looking complexion Glycolic Acid removes dead skin cells and boosts elasticity to reveal brighter, smoother, more youthful skin 0.05 % Retinaldehyde (a precursor to Retinoic Acid) helps improve skin elasticity and reverse collagen alteration induced by UVA exposure Utilizes unique qualities of: Hydroquinone (2 %) and Kojic Acid address dark spots and skin discolorations including freckles, age and liver spots, pigmentation changes due to pregnancy or the use of oral contraceptives, or as a result of age or sun damage Glycolic Acid helps exfoliate dead skin cells from skin surface and helps to reduce the appearance of dark spots Nordihydroguaiaretic Acid (a powerful antioxidant) fights free radicals harmful to the skin Features a dab-on sponge design for easy use Oil-free DIRECTIONS FOR USE Use twice daily or as directed by your physician. After washing, apply toner to a cotton pad and gently stroke over face and neck. Do not rinse. Apply a small amount to face and neck at night or as directed by your physician. Use daily sun protection during use of this product. Apply a small amount as a thin layer on the affected area twice daily, or as directed by a doctor. If no improvement is seen after 3 months of treatment, discontinue use. Lightening effect of this product might not be noticeable when used on very dark skin. To prevent darkening from reoccurring, avoid sun exposure to treated areas by using a sunscreen with broad spectrum SPF 15 or higher and wearing protective clothing. INGREDIENTS Water, Isopropyl Alcohol, Glycerin, Sodium PCA, Cocamidopropyl Betaine, Polysorbate 20, Methylparaben, Fragrance, Octoxynol-5, Salicylic Acid, Symphytum Officinale Extract, Citric Acid, Hydroxyethylcellulose, Yellow 5. Water, Caprylic/Capric Triglyceride, Glycolic Acid, Mineral Oil, Glyceryl Stearate, PEG-100 Stearate, Squalane, Polyacrylate-13, Sodium Hydroxide, Polyisobutene, BHT, Butylparaben, Disodium EDTA, Phenoxyethanol, Polysorbate 20, RED 33, Retinal, Sorbitan Isostearate. Active Ingredients Hydroquinone 2 % Inactive Ingredients: Water, Propylene Glycol, Isopropanol, Glycolic Acid, Aminomethyl Propanol, Sodium Metabisulfate, Kojic Acid, Sodium Bisulfite, Hydroxyethyl Ethylcellulose, Disodium EDTA, Octoxynol-9, Nordihydroguaiaretic Acid. * Precision Free Acid Value 22 BRIGHTENING for Hyperpigmented Skin

23 Rx Rx Rx Skin Lightening Cream Skin Lightening Gel SunVanish Skin Lightening Cream Broad Spectrum SPF 25 SIZE NET WT. 56 g / 2 OZ. NET WT. 56 g / 2 OZ. NET WT. 56 g / 2 OZ. INDICATION Normal to dry hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation. Normal to oily hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation. Sun exposed hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation. BENEFITS Prescription strength Hydroquinone (4 %) works to lighten dark spots and skin discolorations, including freckles, age and liver spots, pigmentation changes due to pregnancy or the use of oral contraceptives, or as a result of age or sun damage Hydroquinone decreases the production and increases the breakdown of melanosomes in the skin s melanin-producing cells by inhibiting the activity of tyrosinase (enzyme needed for melanin production) Specific moisturizing formula for normal to dry skin Prescription strength Hydroquinone (4 %) works to lighten dark spots and skin discolorations, including freckles, age and liver spots, pigmentation changes due to pregnancy or the use of oral contraceptives, or as a result of age or sun damage Hydroquinone decreases the production and increases the breakdown of melanosomes in the skin s melanin-producing cells by inhibiting the activity of tyrosinase (enzyme needed for melanin production) Oil-free Specific lightweight formula for normal to oily skin Utilizes the lightening and brightening properties of prescription strength Hydroquinone (4 %), which decreases the production and increases the breakdown of melanosomes in the skin s melanin-producing cells by inhibiting the activity of tyrosinase (enzyme needed for melanin production) Works to lighten dark spots and skin discolorations, including freckles, age and liver spots, pigmentation changes due to pregnancy or the use of oral contraceptives, or as a result of age or sun damage Octinoxate and Oxybenzone work together to help protect and prevent sunburn caused by UVA/UVB Contains Broad Spectrum SPF 25 agent to protect the skin from the sun s UVA/UVB rays that can cause repigmentation Not meant for sunbathing and swimming Oil-free DIRECTIONS FOR USE Apply daily to the affected area or as directed by your physician. Apply daily to the affected area or as directed by your physician. Apply daily to area where lightening is desired or as directed by your physician. INGREDIENTS Each gram contains 40 mg of Hydroquinone USP in a cream base of Purified Water, Cetostearyl Alcohol, Glycerin, Petrolatum, Propylene Glycol, Mineral Oil, Sodium Lauryl Sulfate, Sodium Metabisulfite, Sorbic Acid. Each gram contains 40 mg of Hydroquinone USP in a gel base of Purified Water, Propylene Glycol, Carbomer 940, Sodium Bisulfite, Edetate Disodium, Sorbic Acid, Glycerin. Each gram contains 40 mg of Hydroquinone USP with 20 mg of Avobenzone, 75 mg of Octinoxate, 18.6 mg of Octocrylene, and 50 mg Oxybenzone in a cream base of Purified Water, Propylene Glycol, Cetearyl Alcohol, Glycerin, Sodium Lauryl Sulfate, Isopropyl Palmitate, Sodium Metabisulfite, Sorbic Acid, and Disodium EDTA. IMPORTANT SAFETY INFORMATION These products are contraindicated if allergic to hydroquinone or any of the product ingredients. Do not use during pregnancy, breast feeding or in children (12 years and younger) as the safety has not been established. These products contain sulfites that may cause allergic-type reactions (e. g. hives, itching, wheezing, anaphylaxis, severe asthma attack) in certain susceptible persons. Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin and check in 24 hours. Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response, further treatment is not advised. Close patient supervision is recommended. For external use only. Avoid contact with eyes. In case of accident contact, patient should rinse eyes thoroughly with warm water and contact their physician. If no bleaching or lightening effect is noted after 2 months of treatment, Skin Lightening Gel/Cream/SunVanish should be discontinued. Keep out of reach of children. Cream and Gel contain no sunscreen. Use only at night. Use a broad spectrum sunscreen and protective clothing to prevent the bleached areas from repigmentation. For daytime bleaching of unwanted areas, the use of Glytone SunVanish should be considered. Avoid unnecessary sun exposure and wear protective clothing to prevent the bleached areas from repigmentation. BRIGHTENING for Hyperpigmented Skin 23

24 Brightening System This Glytone Brightening System features the new Glytone Enhance Brightening Complex, which works synergistically with Glytone Mild Gel Cleanser and Glytone Night Renewal Cream to visibly improve the appearance of unwanted dark spots. Glytone Sunscreen Lotion Broad Spectrum SPF 40 protects skin from developing and worsening the signs of hyperpigmentation. A complete regimen to cleanse, treat, protect and enhance your skin for a more even and radiant tone. 1 Cleanse and Exfoliate Mild Gel Cleanser Improve Enhance Brightening Complex Protect Sunscreen Lotion Broad Spectrum SPF 40 Renew Night Renewal Cream 24 BRIGHTENING for Hyperpigmented Skin

25 Lightening Systems NORMAL TO OILY/DRY SKIN The Glytone Lightening Systems provide a daily regimen to cleanse, treat, protect and enhance the skin to lighten dark spots and even skin tone. Featuring the new Glytone Enhance Brightening Complex that complements Glytone Mild Gel/Cream Cleanser and Glytone Night Renewal Cream, it visibly improves the appearance of unwanted dark spots for a more even and radiant skin tone. Glytone SunVanish Skin Lightening Cream with Broad Spectrum SPF 25 is intended for day time use. Formulated with hydroquinone, it lightens darkspots and protects the skin from the sun s effects. Glytone Skin Lightening Gel/Cream with 4 % Hydroquinone is intended as a night time treatment to lighten dark spots. Two complete regimens to cleanse, treat, protect and enhance your skin. 1 Cleanse NORMAL TO OILY SKIN Mild Gel Cleanser 1 Cleanse NORMAL TO DRY SKIN Mild Cream Cleanser 2Treat Enhance Brightening Complex 3Treat and Protect SunVanish Skin Lightening Cream Broad Spectrum SPF 25 2Treat Enhance Brightening Complex 3Treat and Protect SunVanish Skin Lightening Cream Broad Spectrum SPF 25 4Treat Skin Lightening Gel 5 Protect and Enhance Night Renewal Cream 4Treat Skin Lightening Cream 5 Protect and Enhance Night Renewal Cream Rx Rx IMPORTANT SAFETY INFORMATION These products are contraindicated if allergic to hydroquinone or any of the product ingredients. Do not use during pregnancy, breast feeding or in children (12 years and younger) as the safety has not been established. These products contain sulfites that may cause allergic-type reactions (e. g. hives, itching, wheezing, anaphylaxis, severe asthma attack) in certain susceptible persons. Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin and check in 24 hours. Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response, further treatment is not advised. Close patient supervision is recommended. For external use only. Avoid contact with eyes. In case of accident contact, patient should rinse eyes thoroughly with warm water and contact their physician. If no bleaching or lightening effect is noted after 2 months of treatment, Skin Lightening Gel/Cream/SunVanish should be discontinued. Keep out of reach of children. Cream and Gel contain no sunscreen. Use only at night. Use a broad spectrum sunscreen and protective clothing to prevent the bleached areas from repigmentation. For daytime bleaching of unwanted areas, the use of Glytone SunVanish should be considered. Avoid unnecessary sun exposure and wear protective clothing to prevent the bleached areas from repigmentation. BRIGHTENING for Hyperpigmented Skin 25

26 ACNE THERAPY for Acne Moderate-to-severe acne affects around 20% of young people... Acne persists into the 20s and 30s in around 64% and 43% of individuals, respectively. The heritability of acne is almost 80% in first-degree relatives. (1) Recommend Glytone Acne Therapy to clear blemishes and keep them away. With the most effective ingredients, Glytone products will help keep your patients acne under control for healthy, clear skin. With options such as non-irritating and oil-free formulas for the face, and a non-greasy, fast-drying spray for larger areas like the back and chest, you can transform your patients acne-prone skin, no matter where acne appears. With your help and Glytone, patients will love their skin. Acne Therapy s Optimal Efficacy and Exclusive Technology Benzoyl Peroxide and Salicylic Acid y43% non-inflammatory lesion reduction (2) y55% inflammatory lesion reduction (2) 3P Technology yfor minimal irritation and effective antibacterial activity using micronized Benzoyl Peroxide in a proven delivery system of prepolymers. Micronized Benzoyl Peroxide ypenetration enhancer Hydro-Gel Matrix yfor continuous hydration and enhanced penetration of actives for optimal efficacy. Self-Foaming Technology yfor prolonged contact of Salicylic Acid with skin for better efficacy. The foam technology can act as a mask when left on for 30 seconds before rinsing. fstrong f CLINICAL EFFICACY AND LESS IRRITATION (1) Epidemiology of acne vulgaris. Bhate K1, Williams HC. Br J Dermatol Mar;168(3): doi: /bjd (2) Based on the meta-analysis of 23 studies including 7,309 patients published in the Journal of the American Academy of Dermatology in July 2010, it is proven that benzoyl peroxide and salicylic acid are the optimal combination for acne treatment. 26 ACNE THERAPY for Acne

27 Acne Cleansers Cleanse the skin and wash away impurities to keep it clear and acne-free Acne Self-Foaming Cleanser Acne Clearing Cleanser SIZE 180 ml / 6.1 FL. OZ. 200 ml / 6.7 FL. OZ. INDICATION For acne skin For normal to oily, acne skin: Acne vulgaris Clogged pores Surface oils BENEFITS A unique, non-irritating formula that washes away surface debris, clears pores and gently exfoliates Self-foaming technology prolongs contact of Salicylic Acid (0.5 %) with the skin for better efficacy in blemish control Clears up acne pimples, blackheads and whiteheads For a deeper mask-like cleanse, leave on for 30 seconds before rinsing. Non-irritating formula Oil-free Paraben-free Salicylic Acid (2 %) washes away surface debris, deeply clears pores and controls oil production to prevent new acne blemishes, blackheads and whiteheads for healthier looking skin Keeps skin smoother, clearer and prepared for further treatment Oil-free, ideal for oily skin DIRECTIONS FOR USE At initial use, turn pump head counter-clockwise to unlock. Dispense a small amount into your hand and mix with a little water. Apply a thin layer over the entire affected area in a circular motion and rinse thoroughly with warm water two times daily. For a masklike effect, leave on for 30 seconds before rinsing. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. Dispense a small amount into your hand and mix with a little water. Apply a thin layer over the entire affected area in a circular motion and rinse thoroughly with warm water two times daily. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. INGREDIENTS Active Ingredients: Salicylic Acid 0.5 % Inactive Ingredients: Water, Methyl Perfluoroisobutyl Ether, Butylene Glycol, Sorbitol, Methyl Perfluorobutyl Ether, Cocamidopropyl Betaine, Sodium Laureth Sulfate, Carrageenan, Cyclopentasiloxane, Cyclohexasiloxane, Phenoxyethanol, Sodium Cocamidopropyl PG- Dimonium Chloride Phosphate, Polyhydroxystearic Acid, Isononyl Isononanoate, Ethylhexyl Isononanoate, Xanthan Gum, Sodium Hydroxide, Perfluorohexane, o-cymen-5-ol, Tetrasodium EDTA, Cinnamomum Zeylanicum Bark Extract, Oryza Sativa (Rice) Bran Extract, Yeast Polysaccharides, Blue 1. Active Ingredients: Salicylic Acid 2 % Inactive Ingredients: Water, Sodium Lauryl Sulfate, Propylene Glycol, Lauramide DEA, Hydroxyethyl Ethylcellulose, Fragrance, Chloroxylenol. ACNE THERAPY for Acne 27

28 Acne Clearing Toner Acne Treatment Lotion Acne 3P Treatment Gel Acne Treatment Spray (Back and Chest) SIZE 240 ml / 8.0 FL. OZ. NET WT g / 2 OZ. NET WT g / 2 OZ. 240 ml / 8.0 FL. OZ. INDICATION For normal to oily, acne skin: acne pimples, blackheads and whiteheads For acne For acne: acne pimples, blackheads and whiteheads For normal to oily, acne skin: Acne vulgaris Clogged pores Surface oils BENEFITS Salicylic Acid (2 %) exfoliates and clears the skin of blemishes Deeply cleanses while controlling oil production and unclogging pores to heal and prevent new acne blemishes, blackheads and whiteheads Keeps skin smoother, clearer and prepared for further treatment Helps keep skin clear of new acne blemishes and allows skin to heal Oil-free Lightweight formula combines exfoliating benefits of Salicylic Acid (1 %) with the soothing properties of Bisabolol to help prevent acne blemishes and reduce potential risks of irritation Hydro-gel matrix provides long term hydration keeping skin soft, smooth and supple Non-irritating formula Matte finish Oil-free Patented time-released micronized Benzoyl Peroxide (5 %) eliminates acne-causing bacteria while minimizing potential irritation Innovative hydro-gel formulation continues to fight acne throughout the day while maintaining skin s moisture and fending off dryness Unplugs pores and reduces oil production Glytone Sunscreen Lotion Broad Spectrum SPF 40 is recommended with use of this product during the day Non-whitening matte finish Non-irritating formula Oil-free Salicylic Acid removes dead surface skin cells, deeply clear and unclog pores to prevent acne blemishes, acne pimples, blackheads and whiteheads on back and chest Convenient, easy-to-use pump which works upside down Quick drying formula Available in 2 sizes: Regular size, 8 FL. OZ. Travel size, 2 FL. OZ. DIRECTIONS FOR USE After cleansing, apply toner to a cotton pad and gently apply over affected area one to three times daily. Do not rinse. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two to three times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. Cleanse the skin thoroughly before applying medication. Cover the affected area(s) with a thin layer one to three times daily, or as directed by your physician. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two to three times daily or as directed by your physician. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. Cleanse the skin thoroughly before applying medication. Cover the affected area(s) with a thin layer one to three times daily, or as directed by your physician. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two to three times daily or as directed by your physician. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor. Spray directly onto cleansed affected areas of the back, shoulders and chest by holding 3 to 6 inches away from the skin one to three times daily. Pump works upside down for optimal application. Let dry prior to putting on clothes. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two to three times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. INGREDIENTS Active Ingredients: Salicylic Acid 2 % Active Ingredients Salicylic Acid 1 % Active Ingredients: Benzoyl Peroxide 5 % Active Ingredients: Salicylic Acid 2 % Inactive Ingredients: Acetone, Benzalkonium Chloride, Fragrance, Isopropyl Alcohol, Polysorbate 20, Red 40, Water, Yellow 5. Inactive Ingredients Water, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Ethoxydiglycol, Propylene Glycol, Glyceryl Laurate, PEG- 100 Stearate, Cyclopentasiloxane, Cetearyl Glucoside, Behenyl Alcohol, Bisabolol, Carnosine, Hydrogenated Lecithin, Oryza Sativa (Rice) Bran Extract, Xanthan Gum, Sodium Hydroxide, Polysilicone-11, Disodium EDTA, Methylparaben, Ethylparaben, Butylparaben, Dimethylacrylamide/ Acrylic Acid/Polystyrene Ethyl Methacrylate Copolymer, Propylparaben, Isobutylparaben, Phenoxyethanol. Inactive Ingredients: Water, Polyacrylamide, C13-14 Isoparaffin, PEG-8/SMDI Copolymer, Phenoxyethanol, Caprylyl Glycol, Laureth-7, Citric Acid. Inactive Ingredients: Benzalkonium Chloride, Isopropyl Alcohol, Polysorbate 20, Water. 28 ACNE THERAPY for Acne

29 Acne Clearing System Acne Treatment Mask SIZE NET WT. 85 g / 3 OZ. INDICATION For normal to oily, acne skin: Acne vulgaris Clogged pores Surface oils Acne Tinted Spot Treatment 60 ml / 2 FL. OZ. For normal to oily, acne skin: Acne vulgaris Clogged pores Surface oils Gentle formulations deliver effective amounts of blemish-fighting ingredients (Salicylic Acid and Benzoyl Peroxide) safely to your skin to cleanse, purify and heal acne. The Acne Clearing System effectively targets: y Acne vulgaris y Surface oils y Clogged pores BENEFITS Sulfur (6.4 %) unclogs and clears pores and inhibits P. acnes bacteria Penetrates deep to reduce breakouts and soothe inflammation Reduces surface oils and helps eliminate blackheads, whiteheads and pimples Oil-free Resorcinol (2 %), a topical keratolytic agent, acts as an antiseptic, blemishcontrolling agent removes dry, roughened tissue Sulfur (8 %) unclogs the pores and inhibit P. acnes bacteria Helps dry and clear acne blemishes Controls breakouts Penetrates pores to help prevent new acne blemishes, pimples, blackheads, and whiteheads Oil-free 1 2 Cleanse Acne Self-Foaming Cleanser Tone Acne Clearing Toner 3Treat Acne 3P Treatment Gel DIRECTIONS FOR USE Before first use, break the safety seal by twisting the inverted cap over the star-shaped seal. Cleanse the skin thoroughly before applying this mask. Apply a generous amount to the entire face and neck, or as directed by your physician. Avoid eyes, nostrils, and lips. Leave on skin for minutes. Remove with lukewarm water in a gentle circular motion. Pat dry. Use one to three times a week, or as directed by your physician. Shake well. Cleanse the skin thoroughly before applying this product. Cover the affected area with a thin layer one to three times daily. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two to three times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day. 4 Treat and Hydrate Acne Treatment Lotion INGREDIENTS Active Ingredients: Sulfur 6.4 % Inactive Ingredients: Bentonite, Isopropyl Alcohol, Kaolin, Zinc Oxide, Water, Glycerin, Calcium Oxide, Sodium Lauryl Sulfate, Cocamide MIPA, Fragrance, Methylparaben. Active Ingredients: Resorcinol 2 %, Sulfur 8 % Inactive Ingredients: Water, Isopropyl Alcohol, Propylene Glycol, Acetone, Titanium Dioxide, Magnesium Aluminum Silicate, Iron Oxides, Octoxynol-9, Xanthan Gum, Fragrance, Chloroxylenol. ACNE THERAPY for Acne 29

30 BODY THERAPY for KP Dry, Rough Skin A beautiful glowing complexion deserves the same radiant glow on the body. Glytone Body Therapy helps to transform your patients skin from head to toe. The exclusive PFAV * system delivers optimal levels of Glycolic Acid to moisturize, retexturize and smooth the skin. Uneven tone, rough patches, dry and ashy looking areas, and those tiny bumps are no match for Glytone body treatments. PFAV * system shows an amount of bioavailable Glycolic Acid in a product, called Free Acid Value. Glytone s exclusive AHA formulations with our PFAV * system will put them on the clear quickly. Keratosis Pilaris (KP) is a common, harmless skin condition caused by hyperkeratinization at the base of the hair follicle, thereby plugging and blocking its opening. KP appears as small, hard bumps, papules and pustules, most commonly on the upper arms and outer thighs, leaving a red appearance and sandpaper-like feel. The Glytone Body Therapy line utilizes high concentrations of Glycolic Acid to help reduce the appearance of: yred, inflamed bumps yrough, bumpy skin Free Acid Values and Their Effects (1) yscaly plaques 20 Reversal in basal cell atypia ycracked heels, elbows and knees Glytone Products Free Acid Value Exfoliating Body Wash 8.8 Exfoliating Body Lotion 17.5 Ultra Softening Heel and Elbow Cream 29.5 Dermal effects of free glycolic acid levels Significant increase in collagen deposition 8-12 Significant increase in cellular turnover 4-8 Moderate increase in cellular turnover 2-4 Smoother softer skin 0-2 Increased moisturization 5 10 Free Acid Value Red, inflamed bumps Rough, bumpy skin * Precision Free Acid Value (1) Barone, Pat. How to Deliver Good Glycolic Acid Therapy, Dermatol Times, Jan BODY THERAPY for KP Dry, Rough Skin

31 Exfoliating Body Wash Reveals softer, suppler skin SIZE 200 ml / 6.7 FL. OZ. INDICATION For rough and dry skin prone to: Red bumps Bumpy skin Scaly plaques Cracked heels, elbows, and knees BENEFITS High concentration of Glycolic Acid exfoliate dead surface skin cells, smooth rough bumps, and even skin s tone and texture for softer, suppler skin Rich lather deeply cleanses, leaving skin feeling fresh, smooth and revitalized Oil-free DIRECTIONS FOR USE Squeeze an ample amount onto a bath pouf or wet washcloth and massage over the entire body, working into a rich lather. Use once a day or as directed by your physician. Concentrate on areas of the body that are the roughest and driest. Rinse thoroughly. For optimal results, follow with Glytone Exfoliating Body Lotion INGREDIENTS Ammonium Lauryl Sulfate, Water, Glycolic Acid, Potassium Hydroxide, Cocamidopropyl Betaine, TEA-Dodecylbenzenesulfonate, Glycerin, Lauramide Oxide, Fragrance, Hydroxyethyl Ethylcellulose, Imidazolidinyl Urea, Lauramide DEA, Methylparaben, Propylparaben, Green 3, Blue 1. * Precision Free Acid Value BODY THERAPY for KP Dry, Rough Skin 31

32 Exfoliating Body Lotion Daily Body Lotion Broad Spectrum Sunscreen SPF 15 Ultra Softening Heel and Elbow Cream SIZE 250 ml / 8.4 FL. OZ. 355 ml / 12 FL. OZ. NET WT. 50 g / 1.7 OZ. INDICATION For keratotic and dry skin: Red bumps Rough, bumpy skin Scaly plaques Cracked heels, elbows and knees For keratotic and dry skin: Red bumps Rough, bumpy skin Scaly plaques Cracked heels, elbows and knees For dry rough skin on heels, elbows and knees: Scaly plaques Cracked skin BENEFITS High concentration of Glycolic Acid exfoliate dead surface skin cells, helping to smooth rough bumps and dry patches Moisturize and correct skin texture imperfections on the body Visibly reduces the appearance of dark spots due to sun exposure Softens and smooths while revealing younger, more vibrant looking skin. Rejuvenates and retexturizes the skin Moisturize and correct skin texture imperfections on the body High concentration of Glycolic Acid and Shea Butter exfoliate dead surface skin cells, helping to hydrate, smooth rough bumps and dry patches, sun protecting agents offer UVA/UVB protection: 12 % Glycolic Complex 2 % Avobenzone 7.5 % Octinoxate 3 % Oxybenzone 1.86 % Octocrylene Visibly reduces the appearance of dark spots due to sun exposure Softens and smooths while revealing younger, more vibrant looking skin Rejuvenates and retexturizes the skin Highly concentrated Glycolic Acid (29.5 PFAV *), Glycerin and protective emollients retexturize, exfoliate, moisturize, smooth, and polish the skin Glycerin Helps to dissolve the dead keratinocytes on the skin patches and calluses, removing the dead surface skin cells and leaving behind a renewed skin surface DIRECTIONS FOR USE Apply daily to arms, back of hands, legs and other parts of the body that require special attention. Not recommended for the face, or immediately after shaving or hair removal. For optimal results, use after bathing with Glytone Exfoliating Body Wash. Apply Daily Body Lotion once daily or as directed by a doctor at least 15 minutes before sun exposure. At least every 2 hours apply a sunscreen with broad spectrum SPF 15 or higher for sun protection. Use a water resistant sunscreen if swimming or sweating Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease the risk, regularly use a sunscreen with a broad spectrum SPF 15 or higher and other sun protection measures including: limit time in the sun, especially from 10 a.m.-2 p.m. wear long sleeve shirts, pants, hats, and sunglasses Gently massage onto dry, callused heels and elbows once a day or as directed by your physician. Leave on for only minutes and rinse with warm water. INGREDIENTS Water, Glycolic Acid, Propylene Glycol, Cetearyl Alcohol, Petrolatum, Glycerin, Potassium Hydroxide, PEG-40 Stearate, Allantoin, Propyl Gallate, Tocopheryl Acetate. Active Ingredients: Avobenzone 2 %, Octinoxate 7.5 %, Octocrylene 1.86 %, Oxybenzone 3 % Inactive Ingredients Water, Glycolic Acid, C12-15 Alkyl Benzoate, Cyclopentasiloxane, Sodium Hydroxide, Glycerin, PEG-100 Stearate, Glyceryl Stearate, Cetearyl Alcohol, Cyclotetrasiloxane, PEG-150 Stearate, Cetyl Alcohol, Dimethiconol, Cholesterol, Butyrospermum Parkii (Shea) Butter, Polyacrylamide, Phenoxyethanol, Cetearyl Glucoside, C13-14 Isoparaffin, Methylparaben, Xanthan Gum, Disodium EDTA, Tocopheryl Acetate, Laureth-7. Water, Glycolic Acid, Cetearyl Alcohol, Stearic Acid, Mineral Oil (Paraffinum Liquidum), Glycerin, PEG-40 Stearate, Tocopheryl Acetate, Magnesium Aluminum Silicate, Potassium Hydroxide, BHT, Methylparaben, Propylparaben. * Precision Free Acid Value 32 BODY THERAPY for KP Dry, Rough Skin

33 KP Kit Smooth and even your skin Easy to use, this 2-step kit incorporates effective PFAV * system to: ysmoothes away unsightly bumps yreveals softer, glowing skin yreduces the appearance of rough skin and scaly plaques yprovides a synergistic effect for quick, visible results 1 Exfoliate Exfoliating Body Wash 2 Retexturize Exfoliating Body Lotion A common benign skin disorder: KP affects 40-50% of the adult population and about 50-80% of all teenagers (1) * Precision Free Acid Value 1) Keratosis Pilaris: Treatment ad Medication, Nili N Alai, MD, FAAD, Dena Thompson, MS, Arash Michael Saemi, MD, Raul Del Rosario, MD, Oct 16, BODY THERAPY for KP Dry, Rough Skin 33

34 RECOVERY for Post-Procedure Care and Hydration Glytone Recovery products nurture tender, post-procedure skin with the highest quality lipid replacements to support and repair the skin s barrier function. They help to calm irritation and keep skin comfortable while recovering. Many procedures are designed to insult the skin in order to trigger healthy remodeling. Glytone Recovery products support the skin during this process by providing the hydration it needs. During professional procedures (chemical peels, microdermabrasion, lasers) essential epidermal lipids are lost and that causes: yskin to become rough and flaky yskin to wrinkle prematurely ydehydration yeasy access for pollution and bacteria to the skin Optimal post-procedure care for compromised skin 34 RECOVERY for Post-Procedure Care and Hydration

35 Soothing Lipid Recovery Cream Hydrating Cream Hydrating Lotion SIZE 60 ml / 2 FL. OZ. NET WT. 50 g / 1.7 OZ. 60 ml / 2 FL. OZ. INDICATION For use post-aesthetic procedure: Lasers Chemical peels Microdermabrasions For use post-aesthetic procedure: Lasers Chemical peels Microdermabrasions For use in complement to Glytone treatments as well as post-aesthetic procedures: Lasers Chemical peels Microdermabrasions BENEFITS Omega-rich Camelina Oil helps protect and preserve the skin s lipid barrier function Omega-3 and Omega-6 fatty acids assist in barrier repair Adds epidermal lipids and replenishes skin s natural elements Sodium Hyaluronate helps in repairing skin tissue and enhances skin s moisture retention Retinyl Palmitate (Vitamin A derivative) and Vitamin E provide natural antioxidant benefits and help regulate cell functions Shea Butter, Glycerin and Vegetal Squalane help hydrate and moisturize Rehydrates and calms skin. A rich formula indicated for skin suffering from excessive dryness caused by topical and oral treatments or aesthetic procedures Utilizes the hydrating qualities of Glycerin and Sorbitol to help moisturize and soothe dry skin adjusting to the use of active ingredients Lightweight, non-greasy formula Contains a powerful combination of ingredients: Allantoin: a natural moisturizing and keratolytic agent that enhances the desquamation of upper layers of the skin with anti-irritating and soothing qualities to protect the skin Soluble collagen: skin conditioning protein responsible for skin strength that helps the skin to recover after aggressive damages Elastin: protein that helps improve skin s elasticity and hydration Glycerin: skin-identical ingredients that helps maintain skin s outer barrier and prevent dryness or scaling Perfect solution for skin that has been stressed by topical treatments or procedures Oil-free DIRECTIONS FOR USE Apply liberally as often as needed or as directed by your physician. Apply liberally as often as needed or as directed by your physician. Apply liberally as often as needed or as directed by your physician. INGREDIENTS Water, Butylene Glycol, Butyrospermum Parkii (Shea) Butter, Glyceryl Stearate, Glycerin, Camelina Sativa Seed Oil, Squalane, Cyclopentasiloxane, Stearic Acid, Cetearyl Alcohol, Batyl Alchohol, Methylparaben, Propylparaben, Sodium Hyaluronate, Ethanolamine, Retinyl Palmitate, BHT. Water, Emulsifying Wax NF, Glycerin, Sorbitol, Isopropyl Palmitate, Ricinus Communis (Castor) Seed Oil, Benzyl Alcohol, Polysorbate 20. Water, Glycerin, Soluble Collagen, Hydrolyzed Elastin, Allantoin, Sorbic Acid, Hydroxyethyl Ethylcellulose, Octoxynol-9. RECOVERY for Post-Procedure Care and Hydration 35

36 SUN PROTECTION for Daily UVA & UVB Protection Sun protection is essential to skin cancer prevention. Glytone s Sun Protection product provides UVA and UVB rays protection against sunburn and premature aging while hydrating. Protect your patients body from head to toe for healthy and youthful skin. UVA and UVB explained UVA Rays: The Aging Rays ydeeply penetrate skin layers, damaging collagen and DNA ycause wrinkling, loss of elasticity and pigmentation yup to 50 times more prevalent than UVB Rays ypenetrates untreated glass Broad Spectrum Protection UVB UVA 290 Burning 320 Aging 400 Zinc Oxide (Z-Cote ) Octinoxate Octisalate Absorbency/Wavelength (nm) UVB Rays: The Burning Rays ymostly affect the outer layer of the skin ycause sunburns that increase the risk of skin cancer yradiation is higher during the summer and during mid-day, but has the potential to burn and cause damage year round UVA Aging Absorbed by Dermis UVB Burning Absorbed by Epidermis 36 SUN PROTECTION for Daily UVA & UVB Protection

37 Sunscreen Lotion Broad Spectrum SPF 40 Protects your skin from harmful UVA and UVB rays by providing broad spectrum protection SIZE 120 ml / 4 FL. OZ. INDICATION SPF 40 Sunscreen Lotion to protect against sunburn and premature aging caused by UVA and UVB rays. Suitable for all skin types for face and body. BENEFITS Reduces the risk of skin cancer and early skin aging if used as directed with other sun protection measures Octinoxate (7.5 %) and Octisalate (2 %) effectively shield the skin from UVB rays which can cause sunburn Micronized Zinc Oxide (Z-Cote ; 7.65 %) provides lightweight and non-whitening sunscreen protection against UVA rays which can cause premature aging Hyaluronic Acid boosts skin s moisture content and reduces the appearance of fine lines and wrinkles Recommended for use in conjunction with aesthetic treatments and procedures such as chemical peels Ideal for daily use on all skin types Fragrance- free Non-irritating Oil-free Non-irritating PABA-free DIRECTIONS FOR USE Apply liberally 15 minutes before sun exposure Reapply: after 40 minutes of swimming or sweating immediately after towel drying at least every 2 hours Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limiting time in the sun, especially from 10 a.m.- 2 p.m. wearing long-sleeved shirts, pants, hats and sunglasses Children under 6 months: Ask a doctor. Other Information: Protect the product in this container from excessive heat and direct sunlight. INGREDIENTS Active Ingredients: Octinoxate 7.5 %, Octisalate 2 %, Zinc Oxide 7.65 % Inactive Ingredients: Water, Isopropyl Myristate, Octyldodecyl Neopentanoate, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Polysorbate 60, Diethanolamine Cetyl Phosphate, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Galactoarabinan, Phenoxyethanol, Hyaluronic Acid, Methylparaben, Propylparaben, Polyether-1, Disodium EDTA, Triethoxycaprylylsilane, Sodium Hydroxide, Citric Acid. SUN PROTECTION for Daily UVA & UVB Protection 37

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40 Transforming solutions for beautiful and healthy looking skin 8 Campus Drive Parsippany, NJ GLYTONE ( ) GLY E08371