Anti-ageing range.

Transcription

1 Anti-ageing range

2 Anti-Ageing When the skin ages, changes in pigmentation, sagging, and wrinkling can be seen. This is mostly due to photoageing, along with other factors such as inflammation, genetics (chronological ageing) and lifestyle (smoking, drinking, stress etc). There are many different ways to treat ageing, from expensive and invasive surgical procedures to less invasive cosmetic treatments. When formulating a cosmetic anti-ageing product, it is important to firstly identify the age category for which the product will be marketed as skin at 25+ (first signs of ageing) has very different needs to skin at 35+ (fine lines), 45+ (menopausal skin) and 55+ (mature skin). This is due to differing collagen levels, thickness of the epidermis/dermis, whether the skin is greasy or dry and so on; using just one active is never enough. Speed of efficacy is also an important factor to consider, as consumers are impatient and often do not want to wait 14 days or more to see a result. Here is where instant skin tighteners and optical blurring agents have their place. These should ideally be complimented by actives that work on a more biological level but can take 14 days or more to work. Our ever ageing population is willing to try anything to stay looking young. So in this very affluent and ever expanding market sector, it is vital that brands stay ahead of the game by ensuring the latest technologies and actives are used. Our partners launch at least one new active per year helping you, our valued customer, to stay ahead of the game. To help guide you through the many options for this area, we at Infinity Ingredients have categorised our actives by age. Happy reading and please contact one of our team should you need more help, advice or samples.

3 25+ The aim of this age category is to keep the skin well moisturised and radiant looking. Fine lines and wrinkles are generally not visible until 30+. CYTOFRUIT WATERS Lemon (INCI: Citrus Limon Fruit Extract) is an organic certified water from Lemon fruits harvested in Mediterranean organic fields. Rich in Vitamin C, Potassium and Citric Acid, Lemon fruits cleanse and exfoliate dull and oily skins, whilst refreshing and quenching the skin s thirst to provide a radiant glow. In addition, Lemon fruit also offers natural anti-bacterial and astringent properties. Thanks to the presence of oligo-elements, this CYTOFRUIT Water could sustain skin biological benefits through an improvement of cell vitality, a protection against external agents or a physiological improvement. Standard grade (Bio 99) is preserved with Potassium Sorbate. Bio grade is available and is preservative-free. Recommended usage level: 1 100% CYTOFRUIT WATERS Sweet Orange (INCI: Citrus Aurantium Dulsis Fruit Extract) is an organic certified water from Sweet Orange fruits harvested in Mediterranean organic fields. Rich in Vitamin C, Sweet Orange fruits gently awaken the skin with a cocktail of vitamins, whilst providing a re-energising fresh, fruity zest for a reborn skin. Thanks to the presence of oligo-elements, this CYTOFRUIT Water could sustain skin biological benefits through an improvement of cell vitality, a protection against external agents or a physiological improvement. Standard grade (Bio 99) is preserved with Potassium Sorbate. Bio grade is available and is preservative-free. Recommended usage level: 1 100% Exo-H (INCI: Butylene Glycol (and) Alteromonas Ferment Filtrate) restores Hyaluronic acid secretion in aged skin cells, stimulates lipid synthesis, supports the Dermo- Epidermal Junction and induces Filaggrin expression in the skin. Exo-H helps maintain an optimal skin barrier function and has excellent hydrating properties due to its action on natural moisturising factors and lipid synthesis. Making it ideal for dry skin. When used in combination, Exo-H and Exo-T regenerate skin texture and natural hydration for a smooth, radiant and healthy looking skin complexion. Recommended use level: 1-3% INKA MACA (INCI: Propanediol (and) Water (and) Lepidium Meyenii) is a unique, natural, preservative-free and organic certifiable ingredient extracted from Maca. Maca is a native Andean plant that grows over 4,000 metres above sea level. Renowned for its energising effects and its capacity to increase fertility. INKA MACA is a highly beneficial phyto-ingredient with multi-functional properties that help improve skin health and radiance, as well as offering protection against pollution, stress, UV radiation and ageing. Recommended use level: 3-5% Matipure Oil Free (INCI: Magnesium Aluminium Silicate (and) Hydroxy- Ethylcellulose (and) Phospholipids). A unique patented biocompatible complex characterised by highly adsorbent porous micro particles made of Cellulose Magnesium Silicate complexed Phospholipids. When Matipure is applied on the surface of the skin, water slowly evaporates allowing excess sebum to gradually migrate inside particles, providing an immediate matifying (reduces sebum by 40% after 1 hour) and purifying effect. Phospholipids give smoothness to the skin and avoid a drying effect. Recommended use level: 1-5% Miniporyl TM (INCI: Isopentyldiol, Trifolium Pratense (Clover) Flower Extract). Extracted from Red Clover Extract and titrated in Biochanin A to purify and rebalance skin. The enlargement of pores is caused by Corneocytes retaining their nucleus. This leads to abnormal desquamation and accumulation of cell debris, which cause pores to clog. As a result skin loses tonicity and firmness. These effects are further worsened by sun, tobacco, food, bad cleansing etc. Miniporyl TM improves Keratinocyte differentiation to obtain nucleus-free Corneocytes as well as inhibiting 5α-reductase activity to decrease sebum production. Overall the size and appearance of pores is reduced for flawless skin! Recommended usage: Preventative face care: %; Intensive face care: %

4 SalSphere Skin Smoothing (Water, Cocamidopropyl Dimethylamine, Salicylic Acid, Phenoxyethanol, Ethylhexylglycerin). SalSphere Skin Smoothing brightens and smooths the skin to restore a youthful appearance. The technology provides gentle exfoliation (optimises the effectiveness of Salicylic acid in rinse-off as well as leave-on applications) to reduce the appearance of scars and blemishes. Reveals fresher, brighter skin with even tone. Opens pores to prevent future blemishes. SalSphere Skin Smoothing maintains a skin friendly ph making it suitable for daily use skin care and anti-aging products such as cleansers, gels, lotions, and creams. Recommended use: up to 5%

5 35+ Expression lines start to become more permanent and do not disappear once the face is relaxed again. Instant skin tighteners and plumping agents have their place here. ChroNOline (INCI: Glycerin (and) Water (and) Dextran (and) Caprooyl- Tetrapeptide-3) is a biomemitic Tetrapeptide derived from a growth factor, linked to a lipid for higher stability and optimal skin penetration. ChroNOline boosts the production in key components at the DEJ such as Collagen VII, Laminin-5 and Fibronectin for optimal skin support. ChroNOline provides an outstanding reduction of the appearance of fine lines and wrinkles after only 28 days and can be used across all ages starting at 25+ to preserve DEJ and communication between Dermis and Epidermis. Recommended use level: Intensive treatment: 2.5%, Preventive treatment: 1% to 2.5%, Skin repair treatment: 0.3% to 1% ENNACOMPLEX 271 (INCI: Aqua, Propylene Glycol, Alchemilla Vulgaris Extract, Chamomilla Recutita Flower Extract, Equisetum Arvense Extract, Hedera Helix Leaf Extract) is a botanical complex intended to formulate eyelid and eye contour toning preparations. It softens and soothes, tones and restructures the skin, restores elasticity, and reduces eye bags. It is especially recommended for toneless and stressed eyelids. The material is a synergistic blend of Lady s Mantle, Horsetail, Ivy, and Chamomile extracts. A clinical study has been performed to show the efficacy of ENNACOMPLEX 271 in reducing abnormalities in eyelid tone. Recommended use level: 2-10% HydroSal Youth (HS YT) (INCI: Ethylhexyl Palmitate, Silica Dimethyl Silylate, Butylene Glycol, Caprylyl Glycol, 2-Phenoxyethanol, Hexylene Glycol, Sodium Hyaluronate, Niacinamide). HS YT is an encapsulation technology comprised of tiny sub-micron spheres. Hyaluronic acid and Vitamin B3 are infused within the porous core of the sphere, which is surrounded by a polymeric shell. The shell is designed to enhance adhesion to the skin and sustain the release of these powerful wrinklefighting ingredients, in order to help attain long-lasting benefits. HydroSal Youth (HS YT) can be used in many anhydrous products, such as masks, serums, or eye creams. Skincare products containing HS YT not only plumps and moisturises the skin, but it also helps to heal and soothe inflammation. Furthermore, the technology can mask and improve fine lines and wrinkles, providing long-lasting results on aged or mature skin. Recommended inclusion level: % INKA CAMU CAMU (INCI: Propanediol (and) Water (and) Myrciaria Dubia Fruit) is a unique, natural, preservative-free and organic certifiable ingredient, extracted from Amazonian Camu camu fruit. Camu camu fruit offers one of the richest natural sources of Vitamin C, which provides the skin with an important antioxidant capacity against free radicals, which are wellknown to be one of the main causes of premature ageing. Camu camu also provides skin luminosity and prevents collagen and elastin degradation. Recommended use level: 1-10% INKA TOCHE (INCI: Propanediol (and) Water (and) Uncaria Tomentosa Bark). Cat s claw is traditionally used in spiritual diseases, to remove the disturbances between spirit and body. In cosmetics, it defends the skin against cellular oxidation and elastin degradation, protecting the skin from premature ageing and inflammation. Recommended use level: 1-10% INKA YACON (INCI: Propanediol (and) Water (and) Smallanthus Sonchifolius) is an innovative natural ingredient from the Andean region with traditional use that can help reinforce the skin s support structure, stimulating the production and reducing the degradation of collagen leaving the skin smoother and plumper. Recommended use level: 3-5% Liftessence Nature (INCI: Water (and) Glycerin (and) Cyathea Cumingii Leaf Extract) is a natural instant skin tightener from Polysaccharides found in a New Zealand Fern. Its specific Polysaccharide composition provides a mechanical lifting effect, which immediately reduces the appearance of fine lines and enhances skin biochemical properties without flaking. Suitable for neck and eye applications. Recommended use level: 1-2%

6 Mamaku Vital Essence (INCI: Water (and) Cyathea Medullaris Leaf Extract. Nature PF:Water (and) Glycerin (and) Cyathea Medullaris Leaf Extract) is extracted from a large tree fern native to New Zealand. Its unique composition stimulates the renewal of the Epidermal cells and reinforces the Dermal Matrix promoting the synthesis of structural Proteins for a revitalised skin. Recommended use level: 1-3% PrincipHyal CUBE 3 (INCI: Sodium Hyaluronate) is a full-spectrum biotechnological fraction of Sodium Hyaluronate that targets short-term anti-ageing effects. A unique 3-in-1 ingredient which quickly improves the global epidermis health thanks to a strengthening of the barrier function of the skin. Skin shows an immediate lifting effect when evaluated by elasticity, smoothness, number and depth of wrinkles, synthesis of neo-elastin, and a general improvement of the skin aspect. CUBE 3 also enhances skin penetration of other lipophilic and hydrophilic active ingredients to optimise their activity. Recommended use level: 0.5-1% PrincipHyal Difference (INCI: Sodium Hyaluronate) is a full-spectrum biotechnological fraction of Sodium Hyaluronate that targets long-term anti-ageing effects. DIFFERENCE is a specific fraction that targets skin wrinkles, decreasing the appearance of them over time by increasing skin elasticity. This anti-wrinkle activity (clinically evaluated in-vivo on smoothness, roughness, wrinkleness, scaliness, and number of wrinkles) results in an overall visible improvement in global Epidermal health. Recommended use level: 0.5-1% PrincipHyal SIGNAL-10 (INCI: Hyaluronic Acid) is a fast-track moisturiser derived from a stable extremely low molecular weight (standardised at less than 10 kda) oligomer of Hyaluronic Acid. SIGNAL-10 acts very quickly as it permeates more efficiently than classic forms of Hyaluronans. This stimulates the proliferation and regeneration of Fibroblasts, and gives a fast improvement in skin of moisturisation and elasticity. Ideal for developing products where speed is everything and TURBO cosmetics is the concept. Recommended use level: % SalSphere Anti-Ageing Lift (Water, Polyvinyl Alcohol, Sodium Coco-Glucoside Tartrate, Theobroma Cacao (Cocoa) Seed Butter, Beeswax, Euphorbia Cerifera (Candelilla) Wax, Lecithin, Phenoxyethanol, Ethylhexylglycerin, Niacin, Tocopheryl Acetate, Glycerin, Resveratrol, Thioctic Acid, Dimethyl Sulfone, Panax Ginseng Root Extract, Portulaca Oleracea Extract, Palmitoyl Tripeptide-5). SalSphere Anti-Aging Lift (AAL) is an effective technology that instantly reduces the appearance of fine lines and treats wrinkles from within for a long-lasting, younger-looking appearance. SalSphere AAL visibly reduces the appearance of fine lines in as little as 10 minutes and yields a firming sensation that can be perceived long after application. Suitable for leave-on antiaging applications such as creams, lotions, serums, and concealers. Recommended use level: 10% SalSphere Natural Anti-Ageing (Water, Hydroxyethyl Behenamidopropyl Dimonium Chloride, Behenyl Alcohol, Butyrospernum Parkii (Shea Butter) Extract, Euphorbia Cerifera (Candelilla) Wax, Phenoxyethanol, Ethylhexylglycerin, Pyrus Malus (Apple) Fruit Extract, Resveratrol. SalSphere Natural Anti- Aging is a sub-micron technology composed of potent and natural age-fighting Polyphenols, Resveratrol and Procyanidin B2. Resveratrol is a potent polyphenol and antioxidant derived from the skin of red grapes that has been shown to brighten and even out skin tone. Procyanidin B2 from apple extract is another powerful Polyphenol and antioxidant that promotes cell growth and rejuvenation. It also inhibits the formation of Advanced Glycation End-products (AGE) that causes wrinkles and dull skin tone. Ideal for anti-ageing products such as lotions, creams, concealers and cleansers. Recommended use level: 5-10% Songa (INCI: Water (and) Solidago Virgaurea (Goldenrod) Extract) means strength in the Algonquian language. The bear was often chosen as a representation of strength and survival making this an ideal active for men s care. Strength, represented by the bear, is tied to life renewal and survival for Native Americans. Songa is for skin renewal and rejuvenation. It is an organic certified active extracted from the aerial parts of the Solidago Virgaurea flower that enhances the Collagen tensing effect for a firmer and tighter skin, soothes irritated skin and supports healing. Recommended use level: 1-2%

7 45+ Menopausal skin (see specific range leaflet for more ideas on this relatively un-tapped market sector), greasy and spotty skin can often be a problem here due to hormonal imbalances. Transepidermal Water Loss (TEWL) increases due to the skin having a more mono-directional structure rather cross-hatched. Epidermal thickness also decreases due to lower Collagen and Elastin levels resulting in more saggy and wrinkled skin. It is vital to select efficacious moisturising actives to restore the skin barrier as well as treating spots, wrinkles and the effects of gravity (Collagen boosting activity). Age spots also begin to appear. Borealine Expert (INCI: Glycerin, Acer Rubrum Extract) is the unique extract of red maple bark developed by BioForeXtra that allows, for the first time, the transfer of Northern forest natural properties to skin care. Borealine Expert is the first fully sustainable cosmetic ingredient obtained from recycled red maple bark that has been clinically tested to reduce the appearance of wrinkles, whilst increasing skin firmness and elasticity to reduce the signs of ageing. Recommended use level: % COLLAGENNA H (INCI: Aqua, Hydrolysed Collagen) has been developed with complete respect for the environment. It is an aqueous solution of 0.6% pure Hydrolysed Collagen extracted from fresh fish skin by-products coming from fishes (cod, haddock, plaice) of the Atlantic Ocean. Once processed and purified, the product comprises of Polypeptides with a molecular weight between 2,000 and 20,000 Daltons. COLLAGENNA H is very rich in essential amino acids such as Proline, Hydroxyproline, Glycine and Alanine. These amino acids are a part of the NMF (Natural Moisturising Factor) and contribute to maintain a good moisture level within the skin. They also have a film-forming, restructuring, and antioxidant action. COLLAGENNA H is a moisturising, softening, protecting, and restructuring ingredient for all skin types which brings extra suppleness and brightness to the skin. Recommended use level: 0.3-2% and Cutaneous Metalloproteinases (MMPs). ECM-Protect defends the skin Collagen and Elastin network against the harmful effects of the environment (UV radiation, pollution, cigarette smoke) and ageing. Designed for tired and loose skin, ECM-Protect helps fight the symptoms of actinic ageing and brings back skin firmness and elasticity. Recommended use level: % ENNACOMPLEX 263 (INCI: Aqua, Propylene Glycol, Citrus Medica Limonum Fruit Extract, Equisetum Arvense Extract, Humulus Lupulus Cone Extract, Pinus Pinaster Bark/Bud Extract, Rosmarinus Officinalis Leaf Extract) is a botanical complex which softens, tones and firms the skin, clears the complexion, reduces wrinkles and helps to restore suppleness and elasticity, whilst globally fighting the ageing process. ENNACOMPLEX 263 contains a balanced blend of Rosemary, Hops, Lemon, Horsetail and Pine bark extracts. Recommended use level: 2-10% ECM-Protect (INCI: Water (and) Dextran (and) Trifluoroacetyl Tripeptide-2) is a Peptide that inhibits the enzymatic activity of Elastase

8 INKA YAGUAR (INCI: Propanediol (and) Water (and) Oenothera Rosea Extract). Natural ingredient from the Peruvian Andes that is wild harvested. Traditionally used by the natives to treat bruises. INKA YAGUAR is a novel natural ingredient that can improve the appearance of prematurely aged skin. Its use in cosmetic products is a new way of protection against cellular oxidation and collagen degradation. INKA YAGUAR protects skin cells from oxidative damage that increases premature ageing. Recommended use level: 1-10% Kollaren (INCI: Water (and) Dextran (and) Tripeptide-1) is a biomimetic Peptide derived from a signal Peptide. Kollaren increases the firmness of the skin by activating the Extracellular Matrix Proteins synthesis (Collagen, Elastin, Fibronectin and Laminin). With its tissue repair properties, Kollaren encourages tissue renewal and restores the biomechanical properties of the skin. Kollaren is the perfect tool to fight the ageing process, reduce the appearance of sagging skin, wrinkles and other manifestations of skin aging. Recommended use level: 1-10% Lanablue (INCI: Sorbitol (and) Water (and) Algae Extract) takes its force from the resources of the Cascadia region in North America. Its blue colour (no colour when formulated) is due to the natural pigment of Phytosienine. An extract of Endemic Cyanophyleae harvested in wild conditions, Lanablue has a high content of group B vitamins, amino acids and specific pigments. It acts like natural Retinoids (without the side effects) on Keratinocyte differentiation, thus smoothing and densifying the epidermis. Lanablue, like Retinoids, influences different markers such as: Filaggrin, marker of cell differentiation, it contributes to maintaining skin hydration and liberates natural moisturising factors; Loricrin, marker of Corneocyte differentiation; Calgranulin A, Calgranulin B and Psoriasin, markers of basal proliferation, involved in skin repair process; TIMP 1 (Tissue Inhibitor of Metalloproteinase-1), natural inhibitor of Matrix Metalloproteinase (MMP) which regulates the integrity of the Extracellular structure. Recommended use level: 1-5% MultiSal Multilayer (MS ML) (INCI: Hydrolyzed Corn Starch, Butyrospermum Parkii (Shea Butter) Extract, Cocamidopropyl Dimethylamine, Lactic acid, Hydrated Silica, Phenylethyl Resorcinol, Sodium Hydroxide, Glycerin, Palmitoyl Tripeptide-5) - MultiSal Multilayer (MS ML) is an anti-ageing system composed of multiple functional compartments within a single microsphere, designed to target multiple layers of the skin for an effective and comprehensive skin rejuvenation. The technology contains AHA, Lactic acid to exfoliate and moisturise the skin and a potent antioxidant (Phenylethyl Resorcinol) for brightening along with a unique blend of peptides that reaches the deeper layer of the skin to stimulate collagen synthesis. MS ML is stable in a variety of lotions and creams. Recommended inclusion level: % MultiSal Retinol (Silica, PPG-3 Benzyl Ether Myristate, Retinol, Polysorbate 20, Polyethylenimine, BHT, BHA, Lauryl Laurate, Zea Mays (Corn) Starch, Hydrolyzed Corn Starch, Hydrolyzed Corn tarch Octenylsuccinate). Retinol has been utilised extensively as an anti-wrinkle therapy. The molecule acts by inducing glycosaminoglycan and collagen synthesis, rejuvenating the firmness and youthful appearance of skin. A challenge regarding the use of Retinol is its susceptibility to oxidation, which ultimately reduces the potency and limits effectiveness. Due to its ability to enhance skin turnover, Retinol can cause irritation on consumers with sensitive skin. MultiSal technology is based on double-layered encapsulation of retinol. The microsphere ruptures when the lotion is rubbed into the skin, releasing the sub-micron spheres inside. The core is comprised of botanical lipophilic ingredients that partition into the skin, thus modulating the slow release of the encapsulated retinol over time. MultiSal Retinol reduces the appearance of fine lines in as little as 2 weeks. MultiSal Retinol is recommended for use in anti-aging and skin rejuvenation products including lotions, creams, lip care and cosmetics as well as anti-acne. Recommended use level: 1-2% Progeline (INCI: Glycerin (and) Water (and) Dextran (and) Trifluoroacetyl Tripeptide-2) is a 3 Amino acids Biomimetic Peptide of Elafin, an enzyme inhibitor that regulates the integrity of the Extracellular Matrix. Progeline decreases Progerin (a new aging biomarker involved in skin cellular senescence) synthesis to bring skin cells back to their 20 s. By acting directly on a senescence marker, Progeline clinically improves the appearance of signs associated with skin maturation: sagging, slackness and wrinkles. A NEW STUDY has shown that Progeline stimulates Sirtuin-1 and Sirtuin-3 production which are responsible for cell longevity and lifespan. In addition, it is able to reverse the signs of aging by increasing Pro-collagen I synthesis to the same level of young cells. Progeline provides an anti-gravity lifting effect for a re-contour the jaw-line. In addition, it offers 100% Elastase inhibition; this is important as we cannot stimulate Elastin so we need to protect it. Gold Award winner, In-Cosmetics Recommended use level: Intensive treatment: 2%; Body care: 1%; Preventive care: 0.5 2%

9 SalSphere Resveratrol (Water, Beeswax, Disodium Coco-Glucoside Tartrate, Butyrospermum Parkii (Shea Butter) Fruit, Lecithin, Potassium Sorbate, Resveratrol). SalSphere Resveratrol is an effective solution that utilises natural-identical resveratrol for skin rejuvenation, wrinkle reduction, and skin lightening. Resveratrol is a powerful antioxidant that possesses multiple anti-aging benefits for the skin. Specifically, it is a potent scavenger that helps to keep skin cells free from the harmful effects of free radicals. It has also been shown to have the ability to brighten the skin and even out its tone. Additionally, it is an anti-inflammatory that can help reduce redness and the visibility of scars. SalSphere technology effectively shields Resveratrol from oxidative forces and maintains the esthetics of final product formulations. The main challenge with using resveratrol in a topical formulation is that it oxidises rapidly. When this occurs,the product discolors to a dark brown color.suitable for skin care and anti-aging applications: leave-on face and body products such as lotions, serums, and creams. Recommended use level: 5-10% SWT-7 TM (INCI: Maltodextrin, Swertia Chirata Extract) is an ultra-hightech active inspired by advanced regenerative medicine that boosts self-repair system of the skin and targets fast (up to 7 days) skin tissue recovery. It has a biomimetic action on adipose-derived stem cells featuring specific factors that ensure cell-to-cell communication. Visible results on vertical lines (responsible for tired and sad facial expression), wrinkles, volume, skin texture and lip lines. Recommended use level: 0.5 2% SalSphere Skin Smoothing (Water, Cocamidopropyl Dimethylamine, Salicylic Acid, Phenoxyethanol, Ethylhexylglycerin). SalSphere Skin Smoothing brightens and smooths the skin to restore a youthful appearance. The technology provides gentle exfoliation (optimises the effectiveness of Salicylic acid in rinse-off as well as leave-on applications) to reduce the appearance of scars and blemishes. Reveals fresher, brighter skin with even tone. Opens pores to prevent future blemishes. SalSphere Skin Smoothing maintains a skin friendly ph making it suitable for daily use skin care and antiaging products such as cleansers, gels, lotions, and creams. Recommended use: up to 5% Sculptessence (INCI: Water (and) Glycerin (and) Linum Usitatissimum (Linseed) Seed Extract. Bio: Betula Alba Juice (and) Glycerin (and) Linum Usitatissimum (Linseed) Seed Extract). Starting at about 45 years of age, skin dehydration and a decrease in dermal constituents are observed leading to a loss of skin substance and density. The skin becomes thinner and less toned, the cheeks lose volume and a sagginess of the skin appears along the jaw line. Sculptessence is a natural remodeller derived from Linseed, which compensates for ageing disorders in three ways of actions: skin hydration, stimulation of GAG s synthesis and protection of Collagen. Its unique Polyholosides hydrate skin and reverse sagging disorders to redesign the outline of the face without the need for surgery. Recommended use level: 3-5%

10 Age Spots ß-White (INCI: Water (and) Butylene Glycol (and) Hydrogenated Lecithin (and) Sodium Oleate (and) Oligopeptide-68 (and) Disodium EDTA) is a TGF-ß Biomimetic peptide encapsulated in a Liposome vehicle. It differentiates itself from other traditional whitening agents with its unique inhibitory action on the MITF (responsible for Tyrosinase and the enzymes involved in the pigment cascade TRP-1 and TRP-2) cellular pathway to decrease constitutive and facultative pigmentation, allowing optimal whitening and lightening effect with an excellent safety profile. Compatible with AHA to enhance exfoliation, increase penetration of peptide and aid whitening. Recommended use level: Intensive whitening: 2.5-5%, Lightening care and skin illuminator: 0.5-1%, Corrective care and age spot: 1-2.5%, If combined with an exfoliant: 1% Melanostatine 5 (INCI: Water (and) Dextran (and) Nonapeptide-1) is an Oligopeptide with a high affinity for MC1-R. Melanostatine 5 is a Biomimetic Peptide antagonist specific to α-msh (Alpha Melanocyte Stimulating Hormone). As an antagonist, Melanostatine 5 competes against the natural ligand (α-msh) on its specific receptor (MC1-R) to prevent any further activation of the Tyrosinase, and thus blocking Melanin synthesis. Tyrosinase inhibition reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots. China compliant. Recommended use level: 4-8% ITC Bright (INCI: Dextran, Origanum Vulgare Leaf Extract, Butylene Glycol) provides a prolonged skin luminosity effect from an innovative and patented technology which entraps the Origamum Vulgare Leaf (Oregano) in a natural polymer controlling its release over time as well as aiding stability. Oregano contains Polyphenols which are well known for their strong antioxidant properties as well as lightening and inhibiting Tyrosinase. ITC Bright helps to significantly reduce the number of dark spots after 30 days of application, whilst also acting as a whitening treatment to target pigmentations disorders. ITC Bright improves the overall skin complexion by improving skin radiance and reducing skin redness and dark spots. Recommended use level: % SalSphere Light (Water, Glyceryl Stearate, Alpha Arbutin, Polysorbate 80, Phenoxyethanol, Ethylhexylglycerin, Resveratrol). SalSphere Light is a delivery system of alpha arbutin and resveratrol designed to treat dark spots, melasma, and post-inflammatory hyper-pigmentation on skin. Suitable for leave-on skin care and anti-aging applications such as lotions, concealers, spot treatments, and serums. Recommended use level: 2.5-5% SalSphere Even Skin (INCI: Salicylic Acid, PEG-8, Isostearamidopropyl Ethyldimonium Ethosulfate, Propylene Glycol, Carthamus Tinctorius (Safflower) Seed Oil, Olea Europaea (Olive) Fruit Oil) is designed to gently exfoliate the skin as well as providing a significant increase in exfoliation as compared to free (non-encapsulated) Salicylic Acid (SA) from a wash application. SA is a poorly-soluble ingredient and has always challenged formulation chemists with low solubility and ph levels. SS ES is a revolutionary solution that is easy to use in water and alcohol-free formulations. The encapsulated active is designed to be compatible with commonly used, cost effective carbomer-based thickeners to produce clear products such as, facial wash and lotion. This technology enables creation of new products in a single step, by adding the technology to the prepared base in an easy mixing process. SS ES is highly loaded with SA and can be diluted to any concentration desired. In dermatology and dermo-cosmetics, the technology is best for the treatment of dermatitis, acne, psoriasis, calluses, and more. In the cosmetic area, a lower concentration of SS ES is recommended for daily skin toning, brightening, scar and pore reduction, excess sebum. Recommended use level: Cosmetic: Up to 1.67; OTC: ; Rx: Over 6.67

11 Tyrostat (INCI: Tyrostat-09: Water (and) Glycerin (and) Rumex Occidentalis Extract Tyrostat-11: Water (and) Glycerin (and) Rumex Occidentalis Extract (and) Ascorbic Acid). A natural skin whitening agent from Rumex species native to Northern Canada. It is edible, safe and globally registered. Tyrostat inhibits Tyrosinase and has a similar activity to Kojic acid. As Tyrostat is a plant based skin lightener, composition can change from batch to batch. Therefore every batch is tested for Tyrosinase inhibition efficacy. Tyrostat effectively reduces pigmentation, erythema, tanning and age spots. A skin lightening effect is induced after just 3 weeks. Two grades are available: Tyrostat 09 (offers a minimum of 75% inhibition) and Tyrostat 11 (contains Ascorbic acid and guarantees a 95% inhibition of Tyrosinase). Recommended use level: 1-3%

12 55+ Wrinkles become deeper, the skin barrier thins further and the waste systems within the cells deteriorate. Actives to smoothe, moisturise and restore Collagen levels all have their place within this age range. Adipofill In (INCI: Water (and) Propanediol (and) Ornithine (and) Phospholipids (and) Glycolipids). An L-Ornithine Amino Acid encapsulated in an Ionosome for specific and local action on Adipocytes; this is a remarkable delivery system, designed to mimic lipofilling for maximum and fast results. Adipofill in is able to increase fatty tissue volume for a lipo filling-like effect through a non-invasive method to decrease Nasogenian wrinkles and enhance breast volume. Dubbed a cosmetic push-up bra, Adipofill in provides a fuller, firmer bust to enhance your decollété. Best Innovation Gold winner, 2012 incosmetics. Recommended use level: 0.5-2% CERAFLUID (INCI: Olive Glycerides, Ceramide 3) is an exceptionally easy to formulate liquid Ceramide 3, which shows the highest compatibility with skin components thanks to its natural Olive di- and tri-glycerides base. It provides improved adhesion amongst Corneocytes, thus regulating the skin barrier for water retention and protecting it from external aggression. It also improves skin elasticity and smoothness whilst helping to restore the barrier effect leading to protection and prevention of dehydration. An in-vivo study shows proven efficacy in reducing the appearance of wrinkles. Recommended use level: % ENNACOMPLEX 268 (INCI: Aqua, Propylene Glycol, Centella Asiatica Extract, Equisetum Arvense Extract, Hedera Helix Extract, Potentilla Erecta Extract) is a botanical complex which tones and firms the skin and helps to restore its suppleness and elasticity, especially in the case of wrinkles, eye puffiness (pouches under the eyes), or stretch marks. ENNACOMPLEX 268 uses the synergy of active botanical components (Horsetail, Centella Asiatica, Tormentil and Ivy) which targets connective tissue restoration by stimulating Collagen and Elastin production. Recommended use level: 1 10% Exo-T (INCI: Butylene Glycol (and) Vibrio Alginolyticus Ferment Filtrate). The Exossine line is composed of 3 exotic Polysaccharides from French Polynesia that provide longlasting hydration, smooth skin texture and protect against pollution. Exo-T has demonstrated a higher activity than Retinoic acid in the stimulation of desquamation markers. Exo-T is a potent inducer of differentiation markers; it protects the Collagen network and thus contributes to skin regeneration. Exo-T improves skin smoothness leading to an even skin complexion. Exo-H and Exo-T regenerate skin texture and natural hydration for a smooth, radiant and healthy looking skin complexion. Recommended use level: 1-3% Isoflavones 150 (INCI: Glycine Soja (Soybean) Germ Extract) contains 10 12% Soybean Isoflavones (Daidzin, Genistin, Glycitin and Aglucone) in a concentrated format. Especially designed for advanced anti-aging (60+), it is a safe substitute for the female hormone, Oestrogen. Isoflavones 150 reduces Collagen glycation to decrease wrinkles and improve elasticity whilst decreasing skin blood flow to reduce skin redness and calm sensitive skin. Ideal for mature and menopausal skin. Recommended use level: 1-3% Kollaren (INCI: Water (and) Dextran (and) Tripeptide-1) is a Biomimetic Peptide derived from a signal Peptide. Kollaren increases the firmness of the skin by activating the Extracellular Matrix Proteins synthesis (Collagen, Elastin, Fibronectin and Laminin). With its tissue repair properties, Kollaren encourages tissue renewal and restores the biomechanical properties of the skin. Kollaren is the perfect tool to fight the ageing process, reduce the appearance of sagging skin, wrinkles and other manifestation of skin ageing. Recommended use level: 1-10%

13 MultiSal Triple Action Anti-Ageing (Hydrolyzed Corn Starch, Butyrospermum Parkii (Shea Butter) Extract, Cocamidopropyl Dimethylamine, Lactic acid, Hydrated Silica, Phenylethyl Resorcinol, Sodium Hydroxide, Glycerin, Palmitoyl Tripeptide-5). MultiSal Triple Action Anti-Ageing (TAAA) is a multi-component controlled release system that allows one single application to deliver multiple actives. MultiSal TAAA provides multiple actives in a single, stable delivery vehicle, targeted and sustained release of actives at a skin-friendly ph. MultiSal TAAA makes skin look youthful with the combination of three powerful actives delivered to separate layers of the skin: 1. Alpha-Hydroxy Acid (AHA) to remove dead skin cells, 2. Phenylethyl Resorcinol - an antioxidant effective in regulating pigmentation to brighten the skin. 3. Targeted Tripeptide - to stimulate collagen synthesis and reduce the appearance of wrinkles and fine lines. Suitable for water-based or anhydrous lotions, creams, and serums. Recommended use level: up to 10% Specifeel NH Butters: Avocado (INCI: Persea Gratissima Oil, Palmitic/Stearic Triglyceride). Specifeel NH Butters are nonhydrogenated, stable and unique butters. Avocado Butter is rich in vitamins and helps soften skin. Its fruit components are also known to trigger collagen production, improve skin appearance and barrier effect. Due to its emolliency, it is perfect for mature skins and its film-forming properties relieve dryness and itchiness of specific skins. Recommended usage level: 3-40% Specifeel NH Butters: Rose Hip (INCI: Rosa Moschata Seed Oil, Palmitic/Stearic Triglyceride). Specifeel NH Butters are nonhydrogenated, stable and unique butters. Rose is the symbol of love and is also linked to beauty figures (such as the Egyptian goddess of feminity, Isis). Rose Butter is used for its natural antioxidant and slightly astringent properties. Components are known to improve skin elasticity and slow down premature ageing. Rosehip Butter is a perfect choice for mature, ageing or damaged skins. Recommended usage level: 3-40%

14 All Ages It goes without saying that all good anti-ageing products should contain an SPF (ideally SPF 15), an antioxidant and a good moisturiser. Please see our Surfactant & Emulsifiers range leaflet for inspiration on our novel emulsifiers with phospholipid touch! EffectiveU-T (INCI: Titanium Dioxide, Silica) is a nano-free mineral filter with high SPF, broad-spectrum protection (including UVA) and photo-stability for use in both sun care and colour cosmetic formulations. EffectiveU-T is ideal for suncare preparations and daily protection creams where an SPF is desired. Ecocert certified. Recommended usage level is: 5-20% Elix-IR (INCI: Water (and) Glycerin (and) Polygonum Aviculare Extract). Scientists estimate that the sun is responsible for 90% of premature skin ageing, which is why photoprotection is so important to consider in cosmetic products. Extracted from Knotgrass, Elix-IR is the first botanical active ingredient designed to specifically target Infra Ageing (infrared-induced skin ageing) and to protect the elastic fibres of papillary and reticular Dermis from sun damage, in order to prevent premature ageing appearing after repeated sun exposure. Recommended use level: Preventive anti-ageing care: 0.5-1%; Intensive treatment & protective sun care: 2% EnhanceU-S (INCI: Titanium Dioxide, Zinc Oxide, Silica) is a nano-free mineral filter with high SPF, broad-spectrum protection and photo-stability for use in both sun care and colour cosmetic formulations. EnhanceU-S is ideal for sun care preparations where an SPF is desired. Ecocert certified. Recommended usage level is: 20-25% EnhanceU-T (INCI: Titanium Dioxide, Silica) is a nano-free mineral filter with high SPF, broad-spectrum protection and photostability for use in both sun care and colour cosmetic formulations. EnhanceU-T is ideal for suncare preparations where an SPF is desired. Ecocert certified. Recommended usage level is: 20-25% EnhanceU-T Light (INCI: Titanium Dioxide, Iron Oxide, Silica) is a nano-free mineral filter with high SPF, broad-spectrum protection and photo-stability for use in both sun care and colour cosmetic formulations. EnhanceU-T Light is ideal for colour cosmetics, BB Creams etc., where an SPF with colour is desired. Ecocert certified. Recommended usage level is: 20-25% EnhanceU-T Medium (INCI: Titanium Dioxide, Iron Oxide, Silica) is a nano-free mineral filter with high SPF, broad-spectrum protection and photo-stability for use in both sun care and colour cosmetic formulations. EnhanceU-T Medium is ideal for colour cosmetics, BB Creams etc., where an SPF with colour is desired. Ecocert certified. Recommended usage level is: 20-25% EnhanceU-T Warm (INCI: Titanium Dioxide, Iron Oxide, Silica) is a nano-free mineral filter with high SPF, broad-spectrum protection and photo-stability for use in both sun care and colour cosmetic formulations. EnhanceU-T Warm is ideal for colour cosmetics, BB Creams etc., where an SPF with colour is desired. Ecocert certified. Recommended usage level is: 20-25% EUK-134 (INCI: Ethylbisiminomethylguaiacol Manganese Chloride). The molecule of eternal youth! EUK-134 is a highly purified molecule that mimics Superoxide Dismutase (SOD) and Catalase activities. It scavenges Superoxide free radicals, eliminates Hydrogen Peroxide (H 2 O 2 ) and transforms ROS into water and Oxygen which are benefical for the skin and as a radio therapy treatment ingredient. EUK-134 has the unique and amazing capacity of regenerating itself during its free radical scavenging action. Thereby, EUK-134, by itself, represents a complete nature-mimetic antioxidant system that can be used as an active cosmetic ingredient to limit premature ageing, reduce photo-ageing, protect the skin and its DNA from sun damage, and decrease redness. Recommended use level: %

15 INKA OMEGA OIL (INCI: Plukenetia Volubilis Seed Oil). Traditionally used to heal and relieve muscle and rheumatic pains by rubbing the oil directly onto the body. In skin care, INKA OMEGA OIL reduces the Trans Epidermal Water Loss, improves the barrier function of the skin, normalises the keratinisation process, prevents DNA damage and restores skin softness. Recommended use level: 1-10% INKA TARA (INCI: Propanediol (and) Water (and) Caesalpinia Spinosa Fruit) is a natural ingredient from the Peruvian Andes that has been used in several ways since the pre-hispanic period (preparation of dyes, anti-inflammatory, healing etc). In cosmetics, INKA TARA protects the skin from free radicals that contribute to accumulated skin damage and collagen degradation from extrinsic factors such as UV radiation. Recommended use level: 1-5% Isocell MAP (INCI: Water (and) Alcohol (and) Glycerin (and) Hydrogenated Lecithin (and) Magnesium Ascorbyl Phosphate). Vitamin C is a well known antioxidant that boosts Collagen I and III synthesis to help prevent and fight the ageing process as well as to lighten/brighten the skin. Lucas Meyer have developed Isocell TM MAP to counteract frequently encountered formulation and stability issues associated with Vitamin C. It is an emulsified Vitamin C system for easy formulation and that special Phopholipid touch. Recommended use level: 1-3% Kahai Oil (INCI: Caryodendron orinocense Nut Oil) is a 100% natural anti-ageing oil, extracted by cold pressing the nuts of the Cacay tree. It has a high penetration capability, a dry skin feel, and a mild nutty scent, which fades quickly. Its high content of natural Vitamin E, F & Retinol nourishes, softens and repairs damaged skin. Kahai Oil revitalises the skins radiance, reduces fine lines and wrinkles, and gives it a long lasting hydration. Kahai Oil contains 50% more Vitamin E and twice the amount of Linoleic Acid than Argan oil and it has 3 times more Retinol than Rose Hip Oil. Recommended use level: Various of a patented α-msh biomimetic peptide. The smart lipophilisation technology used in MelinOIL leads to a transparent micro dispersion of the peptide in an oil allowing its formulation into clear oil-based products. MelinOIL binds MC1-R both on melanocytes and keratinocytes to stimulate the natural skin defence system against sun and also stimulate melanin production in the hair bulb to reverse the signs of greying (hair and beards). MelinOIL acts effectively and simultaneously on melanogenesis to improve natural cell UV protection by melanin, on DNA repair to limit photo ageing and on the inflammatory cascade to soothe sun-ravaged skin. Recommended inclusion level 0.5-5% MultiSal Vitamins C & E (MS C&E) (INCI: Sodium Starch Octenylsuccinate, Ascorbic Acid, Tocopheryl Acetate, Hydrated Silica, Beeswax) - Vitamin C (L-Ascorbic Acid) is considered an anti-ageing powerhouse by skincare experts. It reduces wrinkles and fades dark spots to create younger-looking skin. Vitamin C also slows the damage caused by free radicals, which increase the development of wrinkles, fine lines, dryness, and damage. Vitamin E is also known for blocking free radicals from the body, resulting in less wrinkles. MultiSal Vitamins C & E (MS C&E) takes these two wellknown antioxidants and puts them to work to repair skin damage, maintain healthy collagen, and speed up the skin s natural repair systems. MS C&E can be used in a wide variety of products, such as body powders, facial sticks, makeup, and more. Recommended inclusion level: 10% Plerasan Veil500 (INCI: Aqua, Beta-glucan, Sericin). Synergistic combination of beta-glucan and high molecular weight Sericin. This silky anti-pollution shield is designed to prevent extrinsic-induced ageing processes from pollution (PM 2.5 and PM 10 ) and blue light. Recommended inclusion level: 1% MelinOil (INCI: Isopropyl Palmitate, Lecithin, Aqua, Acetyl Hexapeptide-1) MelinOIL is an oil-soluble version

16 Thalassenna (INCI: Plankton Extract, Glycerin) is an extract of Thalassiosira pseudonana, a marine diatome (microseaweed) which has the unique property of being able to concentrate Selenium from the sea during its growth which are stored in the form of Selenoproteins. Selenium is a trace element with strong anti-radical activity, and is therefore a very effective skin protective and UV induced anti-ageing ingredient. Selenium increases the activity of Keratinocytes and Fibroblast Glutathionperoxydase enzymes (GPX and PHGPX) that are essential in the elimination of free radicals involved in the skin photo-ageing process. Thalassenna is also a source of many other beneficial components from the sea such as proteins, amino acids, vitamins and minerals. Recommended use level: 0.5 3% Tensenna (INCI: Triticum Vulgare Gluten) is a complex of vegetal proteins extracted from Wheat, which impart a tensing effect together with moisturising, softening, and antiageing properties. Recommended use level: 10 30%

17 Interested? Then please call one of our team for more information... Andrew Goodwin Managing Director T: M: E: Clare Goodwin Technical Sales Director T: M: E: W: infinity-ingredients.co.uk