DuPont GENENCARE OSMS. From Nature to Nurture

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1 DuPont GENENCARE OSMS From Nature to Nurture

2 GENENCARE From Nature to Nurture

3 GENENCARETM A NATURAL INNOVATION FROM DUPONT People have always looked to nature for inspiration for life-enhancing products. That s still true today, with consumers increasingly interested in the origins and natural credentials of the products they choose. GENENCARE is a growing family of natural, active personal care ingredients, identified and extracted by DuPont to improve performance and enhance the user s experience across a wide range of nurturing skin, hair and color cosmetic applications. We see GENENCARE as a way of unlocking nature s secrets. Through our commitment to innovation and discovery, you can now harness their power for your own formulations and create products that consumers will love, naturally. GENENCARE turning nature into nurture.

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5 INTRODUCING GENENCARETM OSMS Water is at the very heart of life on earth, and nature has developed some incredible strategies for retaining moisture. From the depths of the planet s oceans, through the scorching heat of the desert, to the cells in our own bodies, maintaining the right water balance is essential and osmolytes are nature s key to locking in vital moisture. Osmolytes control the water balance of living cells by attracting and holding on to moisture. And we have harnessed this hidden power of nature to create GENENCARE OSMS. GENENCARE OSMS is made from highly purified plant extracts from renewable sources. It is a product line comprised of natural Osmolytes for skin, hair and color cosmetic applications. Renowned for their water retention and cell protection properties, our GENENCARE OSMS range includes Betaine and Myo-Inositol. These all-natural ingredients not only provide an intense and rapid boost of moisturization and long-lasting effective skin protection, but also enhance the sensory experience of your personal care products. Multi-functional benefits inspired by nature GENENCARE OSMS the best natural active ingredients for your products: - GENENCARE OSMS BA (Betaine anhydrous) - GENENCARE OSMS BH (Betaine monohydrate) - GENENCARE OSMS CC (Betaine Powder) - GENENCARE OSMS MI (Myo-Inositol)

6 GENENCARETM OSMS The natural moisturizer Skincare The natural regulation properties of GENENCARE OSMS help skin retain vital moisture and maintain cell water balance. By improving epidermal cell cohesion, transepidermal water loss (TEWL) is reduced, demonstrating a stronger skin barrier; this allows skin to re-hydrate itself quickly and naturally. Haircare GENENCARE OSMS also delivers multiple moisture-retention benefits in hair applications. Not only does it add strength, gloss, softness and flexibility to hair, it helps protect against scalp flaking and itchiness. Color Cosmetics The graph below shows the benefits of using GENENCARE OSMS in lipstick. GENENCARE OSMS delivers both an immediately noticeable increase in moisturization and a sustained increase in the level of moisture in the lips over time. Delivering Powerful Results Third-party research institute Dermscan tested a formulation of 2% GENENCARE OSMS against a placebo to evaluate the effect on moisturization of the lips over time. The results show that lipstick containing GENENCARE OSMS improves moisturization significantly compared to the placebo, both immediately and 2 hours after application. %* Increase in moisturization Placebo +2% GENENCARE OSMS CC Immediate after application Placebo 2 hours after application +2% GENENCARE OSMS CC Study 14 E0046, June 2014 Dermscan (Poland). * Cutaneous hydration rate variation by Corneometer. Immediate and 2h effect is highly significant (p<0.0001).

7 GENENCARETM OSMS Natural protection GENENCARE OSMS naturally protects skin and hair, helping to keep them healthier for longer. Skincare GENENCARE OSMS strengthens the skin barrier by increasing tight junction integrity and epidermis cell cohesion to help prevent penetration of harmful substances. In addition, its anti-inflammatory properties protect the skin against irritation. Haircare GENENCARE OSMS protects hair against damage from over-heating, coloring, bleaching and straightening, while increasing its strength and elasticity. It s also proven to protect the scalp against irritation caused by surfactants. The graph below shows the ability of GENENCARE OSMS to increase moisture retention in hair, giving it a natural protection which makes it softer, more flexible and less prone to fracturing. Delivering Powerful Results Third-party research institute ISPE (Italy) tested a solution of 4% GENENCARE OSMS in water against a solution containing a comparable amount of glycerin. The results show that the GENENCARE OSMS formulation improved water retention in hair significantly higher than the glycerin alternative. % Increase in water retention area under the curve* % Glycerin 4% GENENCARE OSMS BA Increase in water retention in the hair Study 22/00/00 ISPE. * Water retention evaluated by weight loss (area under the curve).

8 GENENCARETM OSMS Sensory benefits, naturally Consumers don t just want their personal care products to perform they want them to feel good, too. Skincare A key sensory benefit of GENENCARE OSMS is its ability to give formulations a luxurious thickness and consistency. When used in skin products it gives a rich texture and a luxurious, silky feel. It also reduces stickiness and aids in a more even application considerably enhancing the usability of your product. Haircare GENENCARE OSMS also gives wet and dry hair a softer, more conditioned feel leaving it with a natural, shiny appearance. When included in color cosmetics, GENENCARE OSMS provides a softer touch and enhanced intensity and homogeneity. Delivering Powerful Results Whatever your product, with GENENCARE OSMS in your formulation you can help consumers enjoy pleasant sensory experiences as part of their day-to-day routine. The graph below shows how GENENCARE OSMS enhances the thickness and feel of skin products, without compromising on its spreadability. Third-party research institute Sensory Spectrum tested an emulsion containing 4% GENENCARE OSMS against a formulation containing a comparable amount of glycerin and a formulation containing a 50:50 mix of 2% GENENCARE OSMS and 2% glycerin. The results show that the addition of betaine delivers a greater thickness and spreadability, whereas the addition of glycerin reduces the spreadability. This effect is even stronger with the mix of 2% GENENCARE OSMS BA with 2% glycerin. Thickness 9 2% GENENCARE OSMS BA + 2% Glycerin 8 4% GENENCARE OSMS BA 4% Glycerin 7 Control Spreadability

9 What GENENCARETM OSMS means to consumers Consumers demand natural personal care products that offer great performance. GENENCARE OSMS enables you to formulate a wide range of skin care, hair care and color cosmetics that deliver clear, long-lasting benefits. Potential Applications: GENENCARE OSMS BA and BH - Skin care, hair care, body care, baby care, bath & shower, fragrances, men s grooming, oral care, sun care, deodorants, soaps. - Color cosmetics: water-based only (liquid foundation, mascaras, tinted creams, W/O lipsticks). - Compatible in all kinds of emulsions (W/O, O/W), surfactant blends, glycolic and alcoholic products. GENENCARE OSMS CC - Skin care/body care: anhydrous formulations (massage balm, scrubs, face, body and hair oils and butters, lip balms). - Color cosmetics (anhydrous): - Foundation, eye shadows, lipsticks, lip gloss, blush, color cosmetic base. - Powders (loose or compacted), poured, pencils. - Compatible with powders, pigments, oils, silicones, wax and butters. For full product details, please contact your local sales representative.

10 GENENCARETM OSMS The natural choice GENENCARE OSMS is produced solely from renewable raw materials and its natural credentials are recognized globally. It complies with a number of certificates for natural product formulations, including:

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12 To discover more GENENCARE products, the natural step is to visit biosciences.dupont.com/genencare or Copyright 2014 DuPont. All rights reserved., DuPont, and all products with or are registered trademarks or trademarks of E. I. du Pont de Nemours and Company or its affiliates.

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