IJPRD, 2014; Vol 5(12): February-2014 ( ) International Standard Serial Number
|
|
- Magdalene Griffin
- 5 years ago
- Views:
Transcription
1 IJPRD, 2014; Vol 5(12): February-2014 ( ) International Standard Serial Number FORMULATION AND EVALUATION OF MEFENAMIC ACID EMULGEL Teena Oswal* 1, Sonali Naik 1 *1 MET Institute of Pharmacy, MET Complex, Bandra Reclamation, Bandra (west), Mumbai , India. ABSTRACT Emulgels have emerged as a promising drug delivery system for the delivery of hydrophobic drugs and with their use even a hydrophobic drug can enjoy the unique properties of gels. Mefenamic acid 2-[(2,3-dimethylphenyl)amino]benzoic acid is a non-steroidal anti-inflammatory agent. Oral administration of this drug is associated with severe gastrointestinal side effects likeulceration and gastro intestinal bleeding. The solution of this problem lies in the fact that, topically applied NSAIDs are safer than oral NSAIDs. The objective of the study was to prepare an emulgel of Mefenamic Acid using different gelling agents. The emulsion was prepared and it was incorporated in different gelling agents (Carbopol 940, Carbopol 934, Lutrol 127 and Lutrol 87). Evaluation of the Mefenamic Acid emulgel was carried out for Physical appearance, ph, Spreadability, Extrudability, Rheological studies, Drug content and in vitro release. Drug content was found to be uniform in all the formulations. The results demonstrate that the release of the drug is dependent on viscosity of the polymer used. The ph range of Carbopol and Lutrol emulgels were found to be suitable for topical application. The accelerated stability studies were performed according to ICH guidelines for 3 months and the results were found to be stable in varying temperature. Correspondence to Author Teena Oswal 1 MET Institute of Pharmacy, MET Complex, Bandra Reclamation, Bandra (west), Mumbai , India. oswalteena9@gmail.com Key words: Emulgel, hydrophobic drugs, Mefenamic acid, topically applied. INRODUCTION Topical drug delivery systems allow localized administration of the drug anywhere in the body through ophthalmic, vaginal, skin and rectal routes. Drugs may be administered for localized or systemic effect. [1] Gels are created by entrapment of large amounts of aqueous or hydroalcoholic liquid in a network of colloidal solid particles, which may consist of inorganic substances, such as aluminium salts or organic polymers of natural or synthetic origin. They have a higher aqueous component that permits greater dissolution of drugs, and also permit easy migration of the drug through a vehicle that is essentially a liquid, 91
2 compared with the ointment or cream base. In spite of many advantages of gels a major limitation is in the delivery of hydrophobic drugs. So to overcome this limitation emulgels are prepared and with their use even a hydrophobic drug can enjoy the unique properties of gels. [3] In recent years, emulgel formulations have been developed for a number of drugs intended for topical or systemic action. [1] When gels and emulsions are used in combined form the dosage forms are referred as Emulgels. [2] It is prepared by mixing an oil-in-water type or water-in-oil type emulsion with a gelling agent. Direct (oil-in-water) system is used to entrap lipophilic drugs where as hydrophilic drugs are encapsulated in the reverse (water-in-oil) system. Emulgels allow dual control of dug release from the formulation, i.e. emulsion and gel. Incorporation of the emulsion into a gel enhances its stability. [1] Emulsions possess a certain degree of elegance and are easily washed off whenever desired. They also have a high ability to penetrate the skin. Emulgels have several favourable properties such as being thixotropic, greaseless, easily spreadable, easily removable, emollient, nonstaining, water-soluble, and longer shelf life, [3] bio-friendly and pleasing appearance. So Emulgels can be used as better topical drug delivery systems over present systems. Mefenamic acid 2-[(2,3-dimethylphenyl)amino]benzoic acid is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. [4] The primary mechanism of action of NSAIDs is reversible inhibition of the Cyclooxygenase (COX) enzyme responsible for synthesis of prostaglandins, which are mediators of the inflammatory process. Nonsteroidal antiinflammatory drugs (NSAIDs) are among the most commonly prescribed drugs worldwide for patients [5] with rheumatic disease. However like other NSAIDs, oral administration of this drug is also associated with severe gastrointestinal side effects like- ulceration and gastro intestinal bleeding liver and kidney trouble. The solution of this problem lies in the fact that, topically applied NSAIDs are safer than oral NSAIDs. Furthermore, the transdermal route of administration has a high patient compliance, which derives from it being non-invasive and the long interval between applications. [6] Topical administration of NSAIDs offers the advantage of local, enhanced drug delivery to affected tissues with a reduced incidence of systemic adverse effects, such as peptic ulcer disease and GI haemorrhage. [5] MATERIALS & METHODS Materials: Mefenamic acid was received as a gift sample from Flamingo pharmaceuticals Ltd. (Navi-Mumbai, India). Lutrol 127 and Lutrol 87 were procured as gift sample from BASF (Navi-Mumbai, India). Carbopol 940, Carbopol 934, Propylene glycol, Tween 80, Methyl paraben, Propyl paraben, Dimethyl sulfoxide, Ethanol, Triethanolamine were obtained from S.D Fine Chemicals Ltd. (Mumbai, India). Span 80 was supplied by CDH Ltd. (Mumbai, India). Wintergreen oil was purchased from Siddhi aromatics (Mumbai, India). Methods: Preparation of emulgel Gelling agents (Carbopol940, Carbopol934, Lutrol127 and Lutrol 87) were dispersed in purified water. ph was adjusted using TEA. The oil phase of the emulsion was prepared by dissolving Span 80 in light liquid paraffin while the aqueous phase was prepared by dissolving Tween 80 in purified water. Methyl and Propyl paraben was dissolved in propylene glycol whereas drug (Mefenamic Acid) was dissolved in ethanol and DMSO and both solutions were mixed with the aqueous phase. Both the oily and aqueous phases were separately heated to 70 to 80 C; then the oily phase were added to the aqueous phase with continuous stirring until it got cooled to room temperature. Obtained emulsion was mixed with gel in 1:1 ratio with gentle stirring. [7] Various formulations prepared are given in Table no 1. 92
3 Table 1: Composition of emulgel formulations F1 F2 F3 F4 F5 F6 F7 F8 Mefenamic 1% 1% 1% 1% 1% 1% 1% 1% acid Carbopol % 1% Carbopol % 1% Lutrol % 15% - - Lutrol % 18% Light liquid 7.5% 7.5% 7.5% 7.5% 7.5% 7.5% 7.5% 7.5% paraffin Tween % 1.3% 1.3% 1.3% 1.3% 1.3% 1.3% 1.3% Span80 0.5% 0.5% 0.5% 0.5% 0.5% 0.5% 0.5% 0.5% Propylene 5% 5% 5% 5% 5% 5% 5% 5% glycol Ethanol 2.5% 2.5% 2.5% 2.5% 2.5% 2.5% 2.5% 2.5% DMSO 5% 5% 5% 5% 5% 5% 5% 5% Methyl 0.001% 0.001% 0.001% 0.001% 0.001% 0.001% 0.001% 0.001% paraben Propyl paraben 0.003% 0.003% 0.003% 0.003% 0.003% 0.003% 0.003% 0.003% Wintergreen 2% 2% 2% 2% 2% 2% 2% 2% oil Water Q.S. Q.S. Q.S. Q.S. Q.S. Q.S. Q.S. Q.S. Fourier Transform Infrared (FT-IR) Studies FTIR spectra of pure Mefenamic Acid and Gelling agents as shown Figure 1-5 were taken to assure the compatibility between the two. Infrared spectrum was taken (Shimadzu FT-IR system, Japan) by scanning the samples in KBr discs. Figure 1: Infrared Spectra of Mefenamic Acid 93
4 Figure 2: Infrared Spectra of Mefenamic Acid + Carbopol 934 Figure 3: Infrared Spectra of Mefenamic Acid + Carbopol
5 Figure 4: Infrared Spectra of Mefenamic Acid + Lutrol 87 Figure 5: Infrared Spectra of Mefenamic Acid + Lutrol 127 Evaluation Emulgels were evaluated for their physical appearance, ph, viscosity, Spreadability, drug content, in vitro diffusion studies, Extrudability. All studies were carried out in triplicate and average values were reported. Physical Appearance The prepared Emulgel formulations were inspected visually for their colour, homogeneity, consistency, grittiness and phase separation. [8] ph determination The ph of the prepared gellified emulsions was determined by using a digital ph meter. 1g of the gellified emulsion was stirred in distilled water, until a uniform dispersion was formed. It was kept aside for 2 hours. The volume was then made up to 100 ml, i.e. 1% solution of prepared formulation. Then, ph measurement was performed. [9] Spreadability Spreading coefficient was determined by apparatus suggested by Mutimer.It consists of wooden block, which is attached to a pulley at one end. Spreading coefficient was measured on the basis of Slip and Drag characteristics of Emulgel. A ground glass slide was fixed on the wooden block. An excess of Emulgel (about 2 gm) under study was placed on 95
6 this ground slide. Emulgel preparation was then sandwiched between this slide and second glass slide having same dimension as that of the fixed ground slide. The second glass slide is provided with the hook. Weight of one g was placed on the top of the two slides for 5 min to expel air and to provide a uniform film of Emulgel between the two slides. Measured quantity of weight was placed in the pan attached to the pulley with the help of hook. The time (in sec) required by the top slide to separate from ground slide was noted. A shorter interval indicates better Spreading coefficient. It is calculated by using the formula: S = M. L / T Where M = weight tied to upper slide L = length of glass slides T = time taken to separate the slides. [8] Extrudability The Extrudability test was carried out using hardness tester. A 15 gm of gel was filled in aluminum tube. The plunger was adjusted to hold the tube properly. The presence of 1kg/cm 2 was applied for 30 sec. the quantity of gel extruded was weighed. The procedure was repeated at 3 equidistance places of the tube. [10] Rheological studies Viscosity measurements were done on Brookfield viscometer by selecting suitable spindle number and rpm. 50 gm of preparation was kept in 50 ml beaker which was set till spindle groove was dipped and rpm was set and dial reading was measured after 3 minutes. From the reading obtained, viscosity was calculated by using factor. The procedure was repeated three times and observations are recorded as mean. [11] Drug Content Determination Drug concentration in Gellified Emulsion was measured by spectrophotometer. Gellified Emulsion was measured by dissolving known quantity of Gellified Emulsion in solvent (methanol) by Sonication. Absorbance was measured after suitable dilution in UV/VIS spectrophotometer. [12] In vitro release studies The in vitro drug release studies were carried out using a modified Franz diffusion (FD) cell. The formulation was applied on membrane which was placed between donor and receptor compartment of the FD cell. Phosphate buffer ph 7.4 was used as a dissolution media. The temperature of the cell was maintained at 37 C. This whole assembly was kept on a magnetic stirrer and the solution was stirred continuously using a magnetic bead. Sample (1 ml) was withdrawn at suitable time intervals and replaced with equal amounts of fresh dissolution media. Samples were analyzed spectrophotometrically at 285 nm and the cumulative % drug release was calculated. [7] Stability studies Stability studies were carried out at 40 ± 2 C/75 ±5%RH for the all the formulations for 3 months. The emulgels were stored at 40 C/75% RH in collapsible tubes for 3 months. The samples were withdrawn on 0 day and after period of 1 month, 2 months and 3 months. The samples were analyzed for physical appearance, ph and drug content [6].Stability data for all the formulations is discussed in Table no. 9. Table 2: Physicochemical characteristics of Mefenamic Acid Emulgel formulations Sr Formulation Colour Phase Grittiness Homogeneity no code separation 1 F1 White None No Homogenous 2 F2 White None No Homogenous 3 F3 White None No Homogenous 4 F4 White None No Homogenous 5 F5 White None No Homogenous 6 F6 White None No Homogenous 7 F7 White None No Homogenous 8 F8 White None No Homogenous 96
7 Table 3: ph of formulations F1- F8 Sr no Formulation code ph value 1 F1 6.53± F2 6.44± F3 6.58± F4 6.57± F5 6.30± F6 6.46± F7 6.45± F8 6.09±0.06 Table 4: Spreadability coefficient of formulations F1- F8 Sr no Formulation code M (gm) L(cm) T(sec) S=M*L/T 1 F ± F ±1.1 3 F ±1 4 F ± F ± F ± F ± F ±1.15 Table 5: Extrudability of formulations F1- F8 Sr no Formulation code Wt extruded from the tube 1 F1 0.9±0.1 2 F2 0.83± F3 0.53± F4 0.91± F5 1.16± F6 0.91± F7 0.82± F8 0.62±0.1 Table 6: Viscosities of formulations F1-F8 Sr no Formulation code Dial reading Factor Viscosity in centipoise 1 F ,000±0.5 2 F ,666.67± F ,333.33± F ,333.33± F ,000±0.5 6 F ,000±1 7 F ,08,666.7± F ,18,666.7±
8 Table 7: Drug content of formulations F1-F8 Sr no Formulation code Drug content(g) 1 F1 1.01± F2 0.99± F3 1.01± F4 1.01± F5 1.01± F6 1.01± F7 1.00± F8 1.01±0.001 Table 8: % Cumulative drug release of formulations F1-F8 % drug release Time (mins) F1 F2 F3 F4 F5 F6 F7 F Table 9: Stability study data of formulations F1-F8. Sr.no Formulation code Month Appearance ph Drug content 1 F1 0day White day White day White day White F2 0day White day White day White day White F3 0day White day White day White day White
9 4 F4 0day White day White day White day White F5 0day White day White day White day White F6 0day White day White day White day White F7 0day White day White day White day White F8 0day White day White day White RESULTS AND DISCUSSIONS Emulgel formulations were white viscous creamy preparation with a smooth homogeneous texture and glossy appearance as shown in Table no. 2. The ph value of all developed formulation of Carbopol emulgel (F1-F4) were in range of and Lutrol emulgel (F5-F8) were in range of which lies in the normal ph range of the skin as shown in Table no. 3. The value of Spreadability indicates that the gel is easily spreadable by small by small amount of shear. Spreadability of Carbopol emulgels (F1-F4) was in range of 26-32g.cm/sec and Spreadability of Lutrol emulgels (F5-F8) was in range of 7-19 g.cm/sec. indicating spredability of Carbopol 940 emulgel good as compared to Carbopol 934, Lutrol 127 and Lutrol 87 as shown in Table no. 4. The extrusion of the gel from tube is important during its application. Gels with high consistency may not extrude from tube whereas, low viscous gel may flow quickly and hence suitable consistency is required in order to extrude the gel from the tube. Extrudability of Carbopol emulgel 90day White formulation was found to be good as shown in Table no. 5. The Emulgel was rotated at 10 rpm for 10 min with spindle 07. The viscosity of the formulations increases as concentration of polymer increases as shown in Table no. 6. The drug content of the formulated Emulgel was estimated spectrophotometrically at λmax 352. The results were in the limits as shown in Table no. 7. The release profile was shown to get extended upto 6 hrs and steady release patterns were observed throughout the formulations. Carbopol 940% and Lutrol % showed best in- vitro release % and 63.11% respectively as shown in Table no. 8. CONCLUSION: Mefenamic acid was successfully incorporated into the gellified emulsion bases consisting of different gelling agents. From the present investigation that proper selection of polymers and drug is a pre requisite for designing and developing a topical 99
10 drug delivery system. The IR studies suggest that polymer selected i.e. Carbopol 940, Carbopol 934, Lutrol 87 and Lutrol 127 was found to be compatible with Mefenamic Acid. The varying concentrations of four polymers were found to affect the gel parameters like drug release, spreadability and its viscosity. Based on results of evaluation parameters and stability studies Carbopol 940 1% emulgel declared as an optimized batch. ACKNOWLEDGEMENTS: The authors are thankful to Flamingo pharmaceuticals Ltd. for gift sample of Mefenamic Acid. REFERENCES 1. Prajapati M, Patel M, Patel K, Patel N, Emulgels: A Novel Approach To Topical Drug Delivery, International Journal of Universal Pharmacy and Bio Sciences, vol 2(1), 2013, Khullar R, Saini S, Seth N, Rana AC, Emulgels: A Surrogate Approach For Topically Used Hydrophobic Drugs, International Journal of Pharmacy and Biological Sciences, Vol1(3), 2011, Jain A, SP Gautam, Gupta, Jain S, Development and characterization of Ketoconazole emulgel for topical drug delivery, Der Pharmacia Sinica, vol 1(3), 2010, /DB00784[Accessed 18 th July 2013]. 5. Heyneman C, Liday C, Wall G, Oral versus Topical Nsaids in Rheumatic Diseases A Comparison, Drugs, vol 60(3), 2000, Sheikh A, Ali S, Siddiqui A, Zahir Z, Ahmad A, Formulation development and characterization of aceclofenac gel containing linseed oil and ginger oleoresin, International Journal of PharmTech Research, vol 3(3), 2011, Khullar R, Kumar D, Seth N, Saini S, Formulation and evaluation of mefenamic acid emulgel for topical delivery, Saudi Pharmaceutical Journal, vol 20, 2012, Joshi B, Singh G, Rana AC, Saini S, Development and Characterization of Clarithromycin Emulgel for topical delivery. International Journal of Drug Development & Research, vol 4(3), 2012, Thakur N, Pratibha B, Mahant S, Rao R, Formulation and Characterization of Benzoyl Peroxide Gellified Emulsions, Scientia Pharmaceutica, vol 80, 2012, Gallagher S, Trottet L, Heard C, Ketofrofen release from permeation across and rheology of simple gel formulation that stimulate increasing dryness, International journal of pharmaceutics, vol 268, 2003, Thakur V, Prashar B, Arora S, Formulation and in vitro Evaluation of Gel for Topical Delivery of Antifungal Agent Fluconazole Using Different Penetration Enhancers, Drug Invention Today, vol 4(8), 2012, [12]. Joshi B, Singh G, Rana A.C., Saini S, Single V, Emulgel: A Comprehensive Review On The Recent Advances In Topical Drug Delivery, International journal of pharmacy, vol 2(11), 2011, ***** 100
AMERICAN JOURNAL OF BIOLOGICAL AND PHARMACEUTICAL RESEARCH
AMERICAN JOURNAL OF BIOLOGICAL AND PHARMACEUTICAL RESEARCH e-issn - 2348-2184 Print ISSN - 2348-2176 Journal homepage: www.mcmed.us/journal/ajbpr FORMULATION AND EVALUATION OF CELECOXIB EMULGEL FOR TOPICAL
More informationFORMULATION AND EVALUATION OF ITRACONAZOLE EMULGEL FOR TOPICAL DRUG DELIVERY
37 P a g e International Standard Serial Number (ISSN): 2319-8141 International Journal of Universal Pharmacy and Bio Sciences 3(5): September-October 2014 INTERNATIONAL JOURNAL OF UNIVERSAL PHARMACY AND
More informationAim: The aim of the present study is to formulate and evaluate a natural emulgel using Cardiospermum halicacabum
ISSN: 0975-766X CODEN: IJPTFI Available Online through Research Article www.ijptonline.com FORMULATION AND EVALUATION OF HERBAL EMULGEL USING CARDIOSPERMUM HALICACABUM LEAF EXTRACT FOR ANTI ARTHRITIC ACTIVITY
More informationFormulation, Development and In-vitro Evaluation of Terbinafine Hydrochloride Emulgel for Topical Fungal Infection
Research Article Kaushal R. Sabu*, Ganesh D. Basarkar Department of Pharmaceutics, SNJB s SSDJ College of Pharmacy, Neminagar, Chandwad, Nashik, India. *Corresponding author s E-mail: sabu.kaushal@gmail.com
More informationFORMULATION, DESIGN, DEVELOPMENT AND EVALUATION OF EMULGEL FOR TOPICAL DELIVERY OF MELOXICAM IN THE TREATMENT OF RHEUMATOID ARTHRITIS
Page1271 Indo American Journal of Pharmaceutical Research, 2015 ISSN NO: 2231-6876 FORMULATION, DESIGN, DEVELOPMENT AND EVALUATION OF EMULGEL FOR TOPICAL DELIVERY OF MELOXICAM IN THE TREATMENT OF RHEUMATOID
More informationDesign, development and evaluation of solid dispersion incorporated transdermal gel of benzoyl peroxide
2016; 5(7): 13-18 ISSN: 2277-7695 TPI 2016; 5(7): 13-18 2016 TPI www.thepharmajournal.com Received: 01-05-2016 Accepted: 02-06-2016 Jitender Mor Rajinder Mann Bharti Chopra Design, development and evaluation
More informationFormulation of gellified emulsions of Clotrimazole using essential oil from Lavendula angustifolia Miller
World Journal of Pharmaceutical Sciences ISSN (Print): 2321-3310; ISSN (Online): 2321-3086 Published by Atom and Cell Publishers All Rights Reserved Available online at: http://www.wjpsonline.org/ Original
More informationReceived: ; Revised; Accepted: EMULGEL: A NEW DOSAGE FORM FOR TOPICAL DRUG DELIVERY
International Journal of Institutional Pharmacy and Life Sciences 3(3): May-June 2013 INTERNATIONAL JOURNAL OF INSTITUTIONAL PHARMACY AND LIFE SCIENCES Pharmaceutical Sciences Review Article!!! Received:
More informationFormulation Development of Diclofenac Sodium Emulgel Using Aloe vera Gel for Transdermal Drug Delivery System
3858 Int J Pharm Sci Nanotech Vol 10; Issue 5 September October 2017 International Journal of Pharmaceutical Sciences and Nanotechnology Research Paper Formulation Development of Diclofenac Sodium Emulgel
More informationThe Pharmaceutical and Chemical Journal, 2014, 1(3):9-16. Research Article
, 2014, 1(3):9-16 Available online www.tpcj.org Research Article ISSN: 2349-7092 CODEN(USA): PCJHBA Formulation, Development and Characterization of Emulgel of a NSAID S Devesh Kapoor* 1, Ruchi B Vyas
More informationDEVELOPMENT AND EVALUATION OF ANTI-DANDRUFF HAIR GEL
INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACY AND CHEMISTRY Available online at www.ijrpc.com Research Article DEVELOPMENT AND EVALUATION OF ANTI-DANDRUFF HAIR GEL Praveen S. Patil* 1, Vinod M. Reddy 2,
More informationPelagia Research Library. Development and characterization of ketoconazole emulgel for topical drug delivery
Available online at www.pelagiaresearchlibrary.com Der Pharmacia Sinica, 2010, 1 (3): 221231 ISSN: 09768688 CODEN (USA): PSHIBD Development and characterization of ketoconazole emulgel for topical drug
More informationThe Effects of Shear on Neutralized Carbomers in Aqueous Conditions
The Effects of Shear on Neutralized Carbomers in Aqueous Conditions Lyndel Speedy 18/07/2014 With thanks to Ensign Laboratories 1 Abstract Carbomer is the generic name for a class of high molecular weight
More informationInternational Journal of Research in Pharmacy and Life Sciences. International Journal of Research in Pharmacy and Life Sciences
Krishnaveni Manubolu et al, IJRPLS, 2015, 3(2) ): 346 351 ISSN: 2321 5038 International Journal of Research in Pharmacy and Life Sciences Journal Home Page: www.pharmaresearchlibrary.com/ijrpls Research
More informationWorld Journal of Pharmaceutical Research SJIF Impact Factor 5.990
SJIF Impact Factor 5.990 Volume 4, Issue 5, 1260-1271. Research Article ISSN 2277 7105 FORMULATION AND EVALUATION OF ANTIDANDRUFF HAIR GEL FOR TREATMENT OF SEBORRHOEIC DERMATITIS S.P. Dhamane* 1, N.V.
More informationJournal of Drug Discovery and Therapeutics 1 (6) 2013, 72-76
Page72 Journal of Drug Discovery and Therapeutics 1 (6) 2013, 72-76 REVIEW ARTICLE ISSN: 2320-4230 EMULGEL: A COMBINATION OF EMULSION AND GEL *Patel Chirag J 1, Satyanand Tyagi 2, Anil Kumar Gupta 3, Prabhakar
More informationInternational Journal of Scientific Research and Reviews
Research article Available online www.ijsrr.org ISSN: 2279 0543 International Journal of Scientific Research and Reviews Design, Development & Evaluation of Solid Dispersion Incorporated Transdermal Gel
More informationLaraCare A200 Your Multi-Functional Larch Tree Active
Personal Care Consumer Care LaraCare A200 Your Multi-Functional Larch Tree Active INCI Name: Galactoarabinan SAP #: 179796 Key Product Attributes: Reduce Transepidermal Water Loss Reduce appearance of
More informationFormulation and Evaluation of Herbal Emulgel of Pothos scandens Linn for Burn Wound Healing Activity
Formulation and Evaluation of Herbal Emulgel of Pothos scandens Linn for Burn Wound Healing Activity Mohammed Haneefa K.P 1*, Abid 2, Shahima Hanan K 3, Guru Prasad Mohanta 4,Chandini Nayar 5 1, 2, 3 Alshifa
More informationDevelopment and Characterization of Clarithromycin Emulgel for topical delivery
International Journal of Drug Development & Research July-September 2012 Vol. 4 Issue 3 ISSN 0975-9344 Available online http://www.ijddr.in Covered in Official Product of Elsevier, The Netherlands SJR
More informationLaraCare A200 Your Multi-Functional Larch Tree Active
PersonalCare LaraCare A200 Your Multi-Functional Larch Tree Active INCI Name: Galactoarabinan SAP #: 179796 Key Product Attributes: Reduce Transepidermal Water Loss Reduce appearance of fine lines and
More informationSTAGES OF PHARMACEUTICAL MANUFACTURING
STAGES OF PHARMACEUTICAL MANUFACTURING API Finished Product API Primary Packaging Secondary Packaging Excipients Starting Materials (Chemicals) 1 PHARMACEUTICAL MANUFACTURING OF NORMAL DOSAGE FORMS 2 Dosage
More informationDevelopment of Novel Topical Formulations for Anti-aging Effect
Development of Novel Topical Formulations for Anti-aging Effect Dr. Meenal M Rane, Dr. Amrita Bajaj, Kapil Waghela SVKMs Dr. Bhanuben Nanavati College of Pharmacy, Mithibai Campus, Vile Parle, Mumbai,
More informationWhat is THIXCIN R? What is seeding? What is the benefit of using THIXCIN R in combination with BENTONE GEL in my formulation?
Questions & Answers Contents What is THIXCIN R? Where can THIXCIN R be used and what major benefits can be achieved? What is the preferred procedure for dispersing and activating THIXCIN R? What mixing
More informationEssential Elements of Rheology Control
Essential Elements of Rheology Control Richard Giles AkzoNobel Technical Service and Development Manager Europe, Middle East, Africa and India In-cosmetics Barcelona 2015 Outline Today s trends BALANCE
More informationQuick Guide Unguator Technology - Competence from the Start
Quick Guide Unguator Technology - Competence from the Start Determinate mixing parameters, based on traditional pharmaceutical compounding: 1. Classification of the formulation according to its appropriate
More informationChapters 18, 22 & 30 Viscosity-inducing Agents, Ointment Bases and Ointments, Creams, Gels, and Pastes
Chapters 18, 22 & 30 Viscosity-inducing Agents, Ointment Bases and Ointments, Creams, Gels, and Pastes Chapter 18 (Viscosity-inducing Agents) 1. What is Carbomer NF? 2. Carbomer is commonly referred to
More informationElfaMoist AC Humectant
ElfaMoist AC humectant INCI NAME: Acetamidoethoxyethanol Non-tacky, high-performance humectant for deep, instant and long-lasting moisturization, even after one application. INTRODUCTION AkzoNobel s latest
More informationTAGRAVIT TM R1 Encapsulated pure retinol. March 2015
TAGRAVIT TM R1 Encapsulated pure retinol March 2015 Retinol- Background Retinol is a form of Vitamin A having a small molecular structure with MW of 286.45 g/mol. Retinol can penetrate the outer layers
More informationDOWSIL 9040 Silicone Elastomer Blend
Technical Data Sheet FEATURES & BENEFITS Compatible with a variety of lipophilic active ingredients such as fragrances, sunscreens, vitamins, and vitamin derivatives Clear to slightly translucent crosslinked
More informationAristoflex Velvet. Public. Clariant BU ICS Personal Care
Aristoflex Velvet Clariant BU ICS Personal Care 30.10.2013 2 Clariant, BU ICS Personal Care, 30.10.2013 Consumer Insights: Luxury wanted Consumers are looking for more from their everyday products Not
More informationFORMATION OF NOVEL COMPOSITE FIBRES EXHIBITING THERMOCHROMIC BEHAVIOUR
FORMATION OF NOVEL COMPOSITE FIBRES EXHIBITING THERMOCHROMIC BEHAVIOUR L. van der Werff 1,2,3 *, I. L. Kyratzis 1, A. Robinson 2, R. Cranston 1, G. Peeters 1 1 CSIRO Materials Science and Engineering,
More informationProduct Information Oil components: dermofeel sensolv
Product Information Oil components: dermofeel sensolv Product features: - Fast spreading, non oxidizable polar oil - Excellent solvating power for UV-filters and dispersibility of pigments - Silicon-like,
More informationProduct Information Emulsifiers & Surfactants: dermofeel easymuls plus
Product Information Emulsifiers & Surfactants: dermofeel easymuls plus Product features: - O/W-emulsifier for low viscous emulsions - Cold or hot processable - Film forming and caring skin feel - Sunflower
More informationPERSONAL CARE PRODUCT OVERVIEW
PERSONAL CARE PRODUCT OVERVIEW Personal Care Product Overview WeylCare Allantoin The ultimate cell proliferation ingredient Ointments made out of allantoin-rich comfrey roots have been used as wound healing
More informationDISPARLON For Waterborne Systems Rheology, Surface Control and Dispersants
SPECIALTY CHEMICALS DISPARLON For Waterborne Systems Rheology, Surface Control and Dispersants DISPARLON additives are manufactured by Kusumoto Chemicals Ltd. of Tokyo, Japan. Through a technology partnership
More informationMASSOCARE CONCENTRATES The easiest way to develop & manufacture Personal Care products
MASSOCARE Solutions for Success MASSOCARE CONCENTRATES The easiest way to develop & manufacture Personal Care products The MASSOCARE cosmetic ingredients are real solutions to the needs of the Personal
More informationOverview on transdermal drug delivery by semisolid systems: Emulgel * Vinod V, and CH S Vijaya Vani
IJPAR Vol.4 Issue 3 Jul-Sep-2015 Journal Home page: ISSN: 2320-2831 Review article Open Access Overview on transdermal drug delivery by semisolid systems: Emulgel * Vinod V, and CH S Vijaya Vani CMR College
More informationCosmetics. Preparation Guidelines and Model Formulations for Target Markets. Introduction. Types of Cosmetic Products
Cosmetics Preparation Guidelines and Model Formulations for Target Markets Introduction There is a tendency, in the personal care field, for highly customized products. This might be to specific hair types
More informationPREPARATION AND EVALUATION OF HERBAL EMULSION FOR TREATMENT OF DANDRUFF
95 P a g e International Standard Serial Number (ISSN): 2319-8141 International Journal of Universal Pharmacy and Bio Sciences 5(4): July-August 2016 INTERNATIONAL JOURNAL OF UNIVERSAL PHARMACY AND BIO
More informationPharma Research Library. 2013, Vol. 1(1): 28-34
Available online at www.pharmaresearchlibrary.com Pharma Research Library International Journal of Chemistry and Pharmaceutical Sciences 2013, Vol. 1(1): 28-34 Pharma Research Library Formulation and Evaluation
More informationChapter 5 Pharmaceutical formulation and its evaluation
Chapter 5 5.1 Introduction Plants have been used in traditional medicine for several thousand years. Medicinal plants as a group comprise approximately 8000 species and account for about 50 % of all the
More informationTechnological and Biopharmaceutical Characterization of Carbopol-Based Ketoprofen Emulgels
Technological and Biopharmaceutical Characterization of Carbopol-Based Ketoprofen Emulgels Original Article Petya Peneva 1*, Velichka Andonova 1, Teodora Dimcheva 2, Margarita Kassarova 1 1 Department
More informationPerformance is in our nature.
Performance is in our nature. 2 TECHNICAL BULLETIN USP-FCC Propanediol Making Beverages Better, Cheaper and Faster Abstract: USP-FCC propanediol is a bio-based polyol that adds a sweet, cool taste to beverages,
More informationProduct data sheet TRIspire Enhance
Product data sheet TRIspire Enhance A Natural Enhancer for Skin Actives Extracted from the Larch tree harvested in North America, TRIspire Enhance (INCI: Galactoarabinan) is a highly functional polysaccharide.
More informationAMAZE XT POLYMER (28-029A) Dehydroxanthan Gum
AMAZE XT POLYMER (28-29A) Dehydroxanthan Gum Performance naturally Today s consumers are educated, driven to succeed and demanding. They want healthy hair that looks good and feels good. Individuality
More informationHyalurosmooth. by Beauty Creations. Natural fine line and wrinkle filler
Hyalurosmooth by Beauty Creations Natural fine line and wrinkle filler Hyalurosmooth Botanical alternative to hyaluronic acid Smoothing and filling of fine lines and wrinkles by injecting «fillers» such
More informationFormulation and Evaluation of Spironolactone Loaded Emulgel for Topical Application
Formulation and Evaluation of Spironolactone Loaded Emulgel for Topical Application Bhautik Kapadiya *1, Dipti Gohil 1, Dinal Patel 1, Snehal Patel, Chintan Aundhia, Nirmal Shah, Kartik Pandya, Chainesh
More informationSENSOGEL 200 PRE-NEUTRALIZED, ACRYLAMIDE-FREE THICKENER FOR A FRESH, FEATHER-LITE SENSORY
SENSOGEL 200 PRE-NEUTRALIZED, ACRYLAMIDE-FREE THICKENER FOR A FRESH, FEATHER-LITE SENSORY 2 Cranberry Road, Unit A4 Parsippany, New Jersey 07054 Phone: 862-210-8344 Fax: 862-210-8336 Email: sales@applechem.com
More informationSKIN BRIGHTENING SYSTEM THE POWER OF FOAM AND PHOTODAMAGE O F T H E FA C E. Powerful 3-Piece Regimen Kit
SKIN BRIGHTENING SYSTEM THE R E V O L U T I O N A RY POWER OF FOAM C L I N I C A L LY P R O V E N T O T R E AT P I G M E N TAT I O N AND PHOTODAMAGE O F T H E FA C E Powerful 3-Piece Regimen Kit Foam drug
More informationBARNET CORNEOTHERAPY RESURFACID CR. AHA s Normalization of Increased Skin s ph Time Release Technology Ultra Mild Exfoliation
BARNET CORNEOTHERAPY RESURFACID CR AHA s Normalization of Increased Skin s ph Time Release Technology Ultra Mild Exfoliation The information contained in this technical bulletin is, to the best of our
More informationFunctional ingredients HELIOGEL LECIGEL. The versatile gelling agents. Emulsifying properties. Easy-to-use. Sensorial gel-cream textures
Functional ingredients HELIOGEL LECIGEL The versatile gelling agents Emulsifying properties Easy-to-use Sensorial gel-cream textures Heliogel is a patented gelling agent with emulsifying properties conferred
More informationWhat is BENTONE GEL IPM V? What is Isopropyl Myristate? Where can BENTONE GEL IPM V be used? What are the typical use levels?
Questions & Answers Contents What is BENTONE GEL IPM V? What is Isopropyl Myristate? What are the major application benefits? Where can BENTONE GEL IPM V be used? How do I incorporate this product into
More informationWorléeAqua Nail - The simple Way to create outstanding water-based Nail Polishes
- The simple Way to create outstanding water-based Nail Polishes Product Range Product INCI Characteristics 100 200 Base Coat Top Coat Natural Remover Aqua, Polyacrylate-42, Dibutyl Sebacate, PPG-2 Methyl
More informationSurfactant Concentrate Iselux SLC
Surfactant Concentrate Iselux SLC INCI Name: Water (and) Sodium Lauroyl Methyl Isethionate (and) Sodium Lauroamphoacetate (and) Cocamide MIPA (and) Sodium Benzoate Iselux SLC is a concentrated surfactant
More informationProduct Information Hair care: dermofeel P-30
Product Information Hair care: Product features: - Natural hair- and skin-conditioner - Lowers combing forces of wet hair - Skin barrier protecting - Readily biodegradable - 100% naturally derived The
More informationMIGLYOL 840. Excellent light emollient. Alternative to IPM. INCI: Propylene Glycol Dicaprylate/Dicaprate. Excellent light and dry emollient
Excellent light emollient Excellent light and dry emollient Alternative to IPM 1. Description: MIGLYOL 840 is a propylene glycol diester of saturated plant fatty acids with chain lengths of C 8 and C 10.
More informationPERSONAL CARE.
PERSONAL CARE www.primeformulations.com WYCARE conditioning & rheology control cationic polymers for skin & hair care Prime Formulations Ltd provides a range of cationic polymers that enhance the look
More informationZemea Propanediol : Optimizing Formulations Using a Natural Solvent and Humectant. Skincare Ingredients 2013 June 12, 2013
Zemea Propanediol : Optimizing Formulations Using a Natural Solvent and Humectant Skincare Ingredients 2013 June 12, 2013 Denis Burlaud Account Manager, Europe Bob Miller, Technical Consultant DuPont Tate
More informationWhich dissolution media of clindamycin phosphate topical gel
Which dissolution media of clindamycin phosphate topical gel The Borg System is 100 % Retrievable Which dissolution media of clindamycin phosphate topical gel Learn about Clindagel Topical Gel ( Clindamycin
More informationTECHNICAL BULLETIN. Zemea Propanediol: A Natural Solvent for Active Ingredients
TECHNICAL BULLETIN Zemea Propanediol: A Natural Solvent for Active Ingredients Introduction The relative effectiveness of Zemea propanediol as a solvent used to deliver active ingredients and functional
More informationHAIR CARE SAFEELIA WGE-60SP
High Effectiveness, More Stable-Silicone Emulsion for HAIR CARE SAFEELIA WGE-60SP 2010 / 11 / 10 CONTENT Introduction Description of SAFEELIA WGE-60SP Test of Hair Conditioning Effect -Measurement of the
More informationSurface Modified Pigments for Inkjet Ink Applications. Mark Kowalski
Surface Modified Pigments for Inkjet Ink Applications Mark Kowalski Boston Chapter IS&T, May 2001 2 Outline Cabot Corporation and Inkjet Colorant Division Pigment Requirements in Inkjet Inks Pigment Particle
More informationInternational Journal of Research in Pharmacology & Pharmacotherapeutics
International Journal of Research in Pharmacology & Pharmacotherapeutics ISSN Print: 2278-2648 IJRPP Special Issue 1 Oct - Dec - 2016 ISSN Online: 2278-2656 Journal Home page: Research article Open Access
More informationFLORAESTERS CHEMISTRY
Bulletin 3 FLORAESTERS 60 FLORAESTERS CHEMISTRY Natural jojoba oil is actually not an oils but an array of oxidatively stable, liquid wax esters. The dominant molecular structure is a straight chain monoester
More informationWorld Journal of Pharmaceutical Research SJIF Impact Factor 5.990
SJIF Impact Factor 5.990 Volume 4, Issue 5, 2324-2330. Research Article ISSN 2277 7105 FORMULATION AND EVALUTION OF HERBAL ACNE GEL M.Santhosh Aruna*, A.Sravani, V. Resshma, N.Santhi Priya, M.Surya Prabha
More informationSunCat MTA. Safe and Efficient Sunscreen Dispersion
SunCat MTA Safe and Efficient Sunscreen Dispersion % Reaching Ground 95% 5% UVA UVB UVC Causes Aging Sunscreen Protection Causes Burning & Tanning Blocked by Atmosphere 12 STAR SYSTEM SUN PROTECTION FACTOR
More informationRongalit Discharge ST Lq.
Technical Information TI/T Asia June 2011 Page 1 of 6 = Registered trademark of BASF SE Rongalit Discharge ST Lq. Discharge agent for pigment discharge reducing agent for direct printing with vat dyes
More informationLa OLIVE High similarity with Human Sebum
La OLIVE High similarity with Human Sebum PEG, Ethylene oxide FREE Perfect For Sensitive Skin SPF Boosters Today s all natural cosmetics need natural actives as well as natural Emulsifiers. Consumers demand
More informationHybrid PMMA Bead Containing Chemical Sunscreen Filters
Hybrid PMMA Bead Containing Chemical Sunscreen Filters Sung-HO Lee, Jeonghwan Kim, Jangho Park, Sangwook Kim, Jinkwan Park, Sookyung Kim, Sooyoung Lee, Byungcheol Lee SUNJIN Chemical Co. LTD, Korea sungholee@sunjinchem.co.kr
More informationPetroleum Jelly / Vaseline General information and synonyms
Petroleum Jelly / Vaseline General information and synonyms COLOUR: Colour ranges from White to Yellow COMMON NAMES: Petrolatum, Petroleum Jelly, Vaseline, Soft Paraffin, Paraffin Jelly, Petroleum Vaseline
More informationJournal home page:
Page6477 Indo American Journal of Pharmaceutical Research, 2013 ISSN NO: 2231-6876 Journal home page: http:///index.php/en/ INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH EVALUATION OF SELECTED COSMETIC
More informationINCI Name: Cyclopentasiloxane (and) C30-45 Alkyl Cetearyl Dimethicone Crosspolymer (and) PEG/PPG-20/23 Dimethicone
Technical Data Sheet Velvesil Plus Velvesil* Plus Gel INCI Name: Cyclopentasiloxane (and) C30-45 Alkyl Cetearyl Dimethicone Crosspolymer (and) PEG/PPG-20/23 Dimethicone Product Description Velvesil Plus
More informationPERSONAL CARE. INNOVATIVE & NATURAL Functional ingredients based on sugar chemistry
PERSONAL CARE INNOVATIVE & NATURAL Functional ingredients based on sugar chemistry PERSONA INNOVATIVE & NATURAL Functional ingredients based on sugar chemistry L CARE Pack size Ecocert approved Ecocert
More informationAnti-ageing serum, anti-wrinkle action with bioencapsulated hyaluronic acid
LIPOHYAL Facial Care Anti-ageing serum, anti-wrinkle action with bioencapsulated hyaluronic acid High concentration of hyaluronic acid (HA). Great power of penetration, di usion and incorporation into
More informationTEGOSOFT OER. Evonik delivers: 1. Fully based on renewable sources 2. Emollient based on an eco-efficient process 3. Rich and caring skin feel
TEGOSOFT OER Enzymatically produced, vegetable-based ester TEGOSOFT OER is a natural based highly pure cosmetic ester oil. It is produced by the Evonik unique enzymatic process. This emollient imparts
More informationBTI Marketing Ltd. Part A
BTI Marketing Ltd. Telephone 0044 (0)1403 733962 24 Crockhurst e-mail: adrianmellor@btconnect.com Southwater West Sussex RH 13 9XA England VAT No. GB 992 6906 66 Cosmetic Product Safety Report Product(s):
More informationAqua Keep 10SH-NFC. How to Use Guide
How to Use Guide Introduction Aqua Keep 10SH-NFC is an aqueous thickener with an interesting rheology. It forms hazy gels that are structured in bulk but the viscosity breaks on the skin to give a water
More informationPHYSICAL PROPERTIES AND SENSORY ATTRIBUTE OF COCONUT MOISTURIZER WITH VITAMIN E
PHYSICAL PROPERTIES AND SENSORY ATTRIBUTE OF COCONUT MOISTURIZER WITH VITAMIN E Prepared by: LENNY ANAK JALIN Supervisor: ASS. PROF. DR ROJI SARMIDI UNDERGRADUATE RESEARCH DEPARTMENT OF BIOPROCESS ENGINEERING
More informationf a c t s Face gel with Xanthan Gum as a natural thickener
f a c t s Face gel with Xanthan Gum as a natural thickener Introduction In an environment that promotes the metrosexual man, younger men, in particular, have no inhibitions about extending their personal
More informationState of the art ingredients fast friendly service
Product Information Geogard ULTRA Multifunctional specialty additive for cosmetics and toiletries. Description Geogard Ultra is accepted by ECOCERT as a preservative in certified organic cosmetics. As
More informationTEGO Carbomer 140 G TEGO Carbomer G
TEGO 140 G TEGO 141 1 G Convenient granulated viscosity adjusters and builders, emulsion stabilizers Granulated s with numerous advantages: lower dusting, easier to process, higher bulk density First s
More informationQuestions and answers on sodium laurilsulfate used as an excipient in medicinal products for human use
9 October 2017 EMA/CHMP/606830/2014 Committee for Human Medicinal Products (CHMP) Questions and answers on sodium laurilsulfate used as an excipient in medicinal products for human use Draft agreed by
More informationEmulsifier Effects on the Stability of Different Wax Emulsions Abstract Keywords: 1. Introduction
Emulsifier Effects on the Stability of Different Wax Emulsions Emmanuela Kwao Boateng 1* Vladimir. M. Kapustin 2 Dmitry.Y. Makhin 2 1. Department of Chemical Engineering, KNUST Kumasi 2. Gubkin Russian
More informationCharacterization of Glycolic Acid Transdermal Gel: The Impact of Polymeric Base and Co-solvent on Release Pattern
J. Pharm. Biomed. Sci., 2(5)53-58, 2012 2012, TextRoad Publication ISSN 2090 424X Journal of Pharmaceutical and Biomedical Sciences www.textroad.com Characterization of Glycolic Acid Transdermal Gel: The
More informationUnimer U-1946 The smart customized polymer for color & skincare cosmetics
Unimer U-1946 The smart customized polymer for color & skincare cosmetics A new generation of high performance and more effective polymer with unlimited applications to give a new twist to your formula.
More informationLuviskol VA Grades. Technical Information
Technical Information June 2012 Supersedes issue dated July 2009 Luviskol VA Grades 04_050102e-09/Page 1 of 14 Last change WF-No. 119233 = Registered trademark of BASF group The Luviskol VA grades are
More informationGeogard ULTRA Multifunctional specialty additive for cosmetics and toiletries.
Product Information Geogard ULTRA Multifunctional specialty additive for cosmetics and toiletries. I. Preservation Naturally-derived product Broad spectrum protection Globally accepted II. Moisturization
More informationInternational Journal of Institutional Pharmacy and Life Sciences 6(1): January-February 2016
International Journal of Institutional Pharmacy and Life Sciences 6(1): January-February 2016 INTERNATIONAL JOURNAL OF INSTITUTIONAL PHARMACY AND LIFE SCIENCES Pharmaceutical Sciences Original Article!!!
More informationTABLE OF CONTENTS 1. PRODUCT OVERVIEW 3 2. MANUFACTURING PROCESS 3 3. STABILITY AND FORMULATION PROPERTIES 3 4. PRODUCT RANGE 4 5. INCI NOMENCLATURE 4
TABLE OF CONTENTS PAGE 1. PRODUCT OVERVIEW 3 2. MANUFACTURING PROCESS 3 3. STABILITY AND FORMULATION PROPERTIES 3 4. PRODUCT RANGE 4 5. INCI NOMENCLATURE 4 6. GUIDELINE FORMULATIONS Body and Foot Exfoliating
More informationLuvigel EM. Technical Information. Thickener for the production of cosmetic products. = Registered trademark of BASF Aktiengesellschaft
Technical Information September 2007 Supersedes issue dated November 2006 Luvigel EM MEMKH 030701e-03/Page 1 of 10 = Registered trademark of BASF Aktiengesellschaft Thickener for the production of cosmetic
More informationFDP and WCP TREATED PIGMENTS
FDP and WCP TREATED PIGMENTS FDP and WCP TREATED PIGMENTS Must-have treated pigments, with high consistency of the shade, no need for color matching. The color consistency allows you to skip the color
More informationDevelopment of Oil-in-Water Emulsion Containing Tamarind Fruit Pulp Extract I. Physical Characteristics and Stability of Emulsion
Naresuan University Journal 2003; 11(3): 29-49 29 Development of Oil-in-Water Emulsion Containing Tamarind Fruit Pulp Extract I. Physical Characteristics and Stability of Emulsion Jarupa Viyoch*, Napaporn
More informationThe NF contains monographs for six such polymers, carbomers 910, 934, 934P, 940, 941, and 1342.
GELS Gels Gels are semisolid preparations that contain small inorganic particles or large organic molecules interpenetrated by a liquid. The vehicle may be: Aqueous,hydroalcoholic, alcohol based or non
More informationCharacteristic of hydrophobically-modified hydroxypropyl methylcellulose, and application of hair cosmetics.
Characteristic of hydrophobically-modified hydroxypropyl methylcellulose, and application of hair cosmetics. Abstract : Hydrophobically-modified hydroxypropyl methylcellulose (HM-HPMC) is a thickener which
More informationProcedures and Practices for Flexo News Inks
Procedures and Practices for Flexo News Inks SAFETY RULES RAW INK PRESS-READY INK DILUTING THE INK TO PRESS VISCOSITY FALSE VISCOSITY (THIXOTROPY) AUTOMATIC VISCOSITY CONTROL PRESS-READY INK STORAGE INK
More informationABIL EM 180 High performance emulsifier for all types of W/O formulations
ABIL EM 180 High performance emulsifier for all types of W/O formulations Very low usage concentration of down to 0.5 % Excellent stabilization in difficult systems Enhanced performance at high temperatures
More informationGafquat 440, 755N, 755N-P, 755N-O and HS-100, HS-100-O polymers Cationic conditioning copolymers
PRODUCT DATA Consumer Specialties ashland.com NUMBER 4817-1 (Supersedes 4817) Page 1 of 8 Gafquat 440, 755N, 755N-P, 755N-O and HS-100, HS-100-O polymers Cationic conditioning copolymers Introduction Gafquat
More informationAn Immediate Release, Pearlescent, Film Coating System from Colorcon
OPADRY fx Product Information Special Effects Film Coating Systems An Immediate Release, Pearlescent, Film Coating System from Colorcon A distinctive product appearance offers many benefits to the producers
More informationRheomer 33T. Innovative Rheological Agent For Personal Cleansing Solutions. Beauty & Care
Rheomer 33T Innovative Rheological Agent For Personal Cleansing Solutions Beauty & Care Rheomer 33T The future of texture Personal cleansing formulations have become more and more sophisticated over time.
More information