Hyaloveil -P. New Type of Hyaluronic Acid for Hair-Care. Q.P. Corporation Fine Chemical Division

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1 New Type of Hyaluronic Acid for Hair-Care Hyaloveil -P Q.P. Corporation Fine Chemical Division Data in this documents are not to guarantee quality of individual products. Anyone who wishes to transcript, copy or apply for patent the contents of this document is requested to contact us for prior written consent.

2 What is Hyaloveil -P? Q.P. s Hyaloveil -P is a new type of Hyaluronic Acid for Hair-Care with much improved adhesion to the hair. With Hyaloveil -P, we have achieved excellent adhesion to hair in addition to retaining moisture and viscoelasticity of hyaluronic acid s original merits, which means it will not be easily washed off by shampoo. Moisture Veil of Hyaloveil -P coats the surface of dry and damaged hair and keep it moist even after shampoo. It finishes your hair lustrous and graceful with smooth and moderate moisture.

3 1. Mechanism of repairing damaged hair Coating Surface of the hair 1 2 Surface of the hair is normally being charged Minus On the other hand Hyaloveil -P is charged Plus Ⅹ Na or X CH3 n CH2CHCH2N+ CH3 Cl OH CH3 Basic Molecular structure of Hyaloveil -P 3 Hyaloveil P is presumed to adhere to the hair by ionic bond. R

4 2. Adhesion test of Hyaloveil P to the hair I <Method of the test> Hyaloveil -P 1% Solution (labeled with fluorescent dye) normal hair damaged hair (bleached hair) Soaking (40 3 minutes) inse with water Drying Observe the surface of the hair with fluorescent microscope <Test result> The hair originally has fluorescence. (self - fluorescence) Untreated Hair (control) Normal Hair Damaged Hair Treated Hair with Hyaloveil -P Normal Hair Damaged Hair Hyaloveil P treated hair showed stronger fluorescence than the control hair, both in normal and damaged condition, which proved that Hyaloveil -P adhered to the hair and remained these after rinse.

5 2. Adhesion test of Hyaloveil P to the hair II <Test result> <Method of the test> % solution of Hyaloveil -P Damaged hair (bleached hair) Soaking (40 10minutes) Assay after draining the solution* *Measuring the decline in concentration of the solution caused by Hyaloveil P adhesion of the hair there by calculated the volume of Hyaloveil P adhered to 1gram of hair Volume adhered to 1 gram of hair (mg) ヒアルロン酸ヒアロベール-P Conventional Hyaluronic Acid Hyaloveil -P It is proved that Hyaloveil P had stronger adhesion to the hair than conventional Hyaluronic Acid

6 3. Hair s moisture retention test <Method of the test> Hyaloveil P 0.2% solution Damaged hair (Bleached hair) soaking (40 5minutes) rinse with water drying measuring DSC* *DSC (Differencial Scanning calorimeter) <Test result> 15 Moisture contents (%) Untreated hair Treated hair with Hyaloveil -P Evaporation calorie volume of water was determined from the peak of calorie absorption resulted from evaporation of water, thereby moisture contents of the hair was calculated. Moisture contents of the treated hair with Hyaloveil P was higher than that of the untreated which proved that Hyaloveil P has adhered to the hair and worked to retain moisture there.

7 4. Electron Microgram <Method of the test> Hyaloveil -P 1% Solution Damaged Hair (Bleached Hair) Soaking (40 5minutes) insing with water Drying Observation with Scanning Electron Microscope (EMS)

8 4. Electron Microgram Untreated Hair Treated Hair with Hyaloveil -P

9 4. Electron Microgram Untreated Hair Treated Hair with Hyaloveil -P *The lift-ups of cuticles of the hair is repaired on the treated hair with Hyaloveil P *Hyaloveil P is adsorbed on the cuticle layer and it helps cuticles stick together by hydrogen bonding.

10 5. Various application of Hyaloveil -P Application *Hair mist, Hair gel *Liquid hair treatment (leave-on type) *Shampoo, conditioner *Hair treatment, shower gel *Permanent wave solution, *Coloring solution By using hyaloveil -P *ich moisture to the hair *Hair setting ability *Protective coating *Improve the touch (smooth, soft)

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