Automate your FISH and CISH procedures. Specifications EXPANDING HORIZONS

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1 Specificatios Slide Capacity Up to 12 slides per ru Program Capacity Storig up to 40 programs by ames ad umbers Program Optios Deaturatio ad hybridizatio Hybridizatio oly Fixed temperature Temperature Uiformity Withi +/- 1 C Deaturatio Temperature C, 0 30 miutes Hybridizatio Temperature Room temperature, C / 0 99 hours Fixed Temperature Room temperature, C / 0 99 hours Heatig Time C / 2 miutes Coolig Time C / 5 miutes Dimesios Depth: 451 mm (17 i); Width: 228 mm (9 i); Height: 140 mm (5 i) Weight 8.5 Kg Ambiet Operatig Temperature C Pre-Set Voltage V (S2450) or V (S2451) Frequecy Hz EXPANDING HORIZONS The spirit of DakoCytomatio lives i its commitmet to customers ad i its cotiuig efforts to expad horizos i patiet care. As research, sciece ad techology advace aroud the globe, DakoCytomatio embraces iovative breakthroughs from Life Scieces to Diagostics. A leadig i vitro diagostics compay specializig i the idetificatio of cacer markers, the compay offers a diverse product portfolio icludig reagets ad istrumetatio for aatomic ad molecular pathology, pharmacodiagostics ad flow cytometry. For further iformatio please cotact your local DakoCytomatio office: Australia Tel Fax Austria Tel Fax Belgium Tel Fax Caada Tel Fax Czech Republic Tel Fax Demark Tel Fax Frace Tel Fax Germay Tel Fax Irelad Tel Fax Italy Tel Fax Japa Tel Fax The Netherlads Tel Fax Corporate Headquarters: Demark Tel Fax Distributors i more tha 50 coutries Norway Tel Fax Polad Tel Fax Spai Tel Fax Swede Tel Fax Switzerlad Tel Fax Uited Kigdom Tel. (0) Fax (0) Techical Support Tel. (0) Uited States of America Tel Fax Customer Service Tel Techical Support Tel Flow Istrumetatio Tel Fax with product offerigs that cover the cotiuum Automate your ad procedures

2 Automatig Deaturatio ad Hybridizatio i your ad Procedures Elimiates umber of maual steps User-friedly desig Easy to program for a wide rage of probe applicatios Program optios: Deaturatio ad hybridizatio Hybridizatio oly Fixed temperature Capable of storig 40 programs by ames ad umbers Easy ad coveiet slide locatio Fast heatig ad coolig times Temperature uiformity withi +/- 1 C Provides cosistet high-quality results 110 V code S V code S2451 The is a hads-free, co-deaturatio ad hybridizatio istrumet desiged for slidebased fluorescece () ad chromogeic () i situ hybridizatio o histology ad cytology samples. The system reduces the umber of maual steps, ad improves efficiecy, throughput, ad precisio compared to maually performed ISH procedures. The has a 12-slide capacity ad heats ad cools slides through two temperature rages with short ramp times. The system is easy to use for a wide rage of probes ad protocols. The is optimized for DakoCytomatio DNA ad PNA probes for ad. Humidity Cotrol Strips The Humidity Cotrol Strips (code S2452, 20 strips) are specially desiged for the DakoCytomatio istrumet, ad esure cotrolled, high humidity durig the hybridizatio procedure. The strips cosist of a special hydrophilic polymer fiber material with high surface area ad the ability to quickly adsorb ad desorb moisture. cosistet Optimized for DakoCytomatio ad probes / Deaturatio Temperature / Time Hybridizatio Temperature / Time Code Probe Y5200 EBV (EBER) PNA Y1443 GePoit HPV * 92 C / 5 mi K5331 HER2 pharmdx * 82 C / 5 mi Y HPV DNA 92 C / 5 mi Y5202 Kappa/Lambda mrna PNA Y Split Sigal Traslocatio DNA 82 C / 5 mi Y5405 Sub-Deletio Sigal DNA 82 C / 5 mi Y1441 Telomerase (htr) 37 C / 2 hrs K Telomere PNA 80 C / 5 mi RT / 30 mi K5333 TOP2A pharmdx * 82 C / 5 mi *call for availability automatigworkflow The ca be itegrated withi the workflow for laboratories workig with the DakoCytomatio Autostaier or other DakoCytomatio systems.

3 Automatig Deaturatio ad Hybridizatio i your ad Procedures Elimiates umber of maual steps User-friedly desig Easy to program for a wide rage of probe applicatios Program optios: Deaturatio ad hybridizatio Hybridizatio oly Fixed temperature Capable of storig 40 programs by ames ad umbers Easy ad coveiet slide locatio Fast heatig ad coolig times Temperature uiformity withi +/- 1 C Provides cosistet high-quality results 110 V code S V code S2451 The is a hads-free, co-deaturatio ad hybridizatio istrumet desiged for slidebased fluorescece () ad chromogeic () i situ hybridizatio o histology ad cytology samples. The system reduces the umber of maual steps, ad improves efficiecy, throughput, ad precisio compared to maually performed ISH procedures. The has a 12-slide capacity ad heats ad cools slides through two temperature rages with short ramp times. The system is easy to use for a wide rage of probes ad protocols. The is optimized for DakoCytomatio DNA ad PNA probes for ad. Humidity Cotrol Strips The Humidity Cotrol Strips (code S2452, 20 strips) are specially desiged for the DakoCytomatio istrumet, ad esure cotrolled, high humidity durig the hybridizatio procedure. The strips cosist of a special hydrophilic polymer fiber material with high surface area ad the ability to quickly adsorb ad desorb moisture. cosistet Optimized for DakoCytomatio ad probes / Deaturatio Temperature / Time Hybridizatio Temperature / Time Code Probe Y5200 EBV (EBER) PNA Y1443 GePoit HPV * 92 C / 5 mi K5331 HER2 pharmdx * 82 C / 5 mi Y HPV DNA 92 C / 5 mi Y5202 Kappa/Lambda mrna PNA Y Split Sigal Traslocatio DNA 82 C / 5 mi Y5405 Sub-Deletio Sigal DNA 82 C / 5 mi Y1441 Telomerase (htr) 37 C / 2 hrs K Telomere PNA 80 C / 5 mi RT / 30 mi K5333 TOP2A pharmdx * 82 C / 5 mi *call for availability automatigworkflow The ca be itegrated withi the workflow for laboratories workig with the DakoCytomatio Autostaier or other DakoCytomatio systems.

4 Automatig Deaturatio ad Hybridizatio i your ad Procedures Elimiates umber of maual steps User-friedly desig Easy to program for a wide rage of probe applicatios Program optios: Deaturatio ad hybridizatio Hybridizatio oly Fixed temperature Capable of storig 40 programs by ames ad umbers Easy ad coveiet slide locatio Fast heatig ad coolig times Temperature uiformity withi +/- 1 C Provides cosistet high-quality results 110 V code S V code S2451 The is a hads-free, co-deaturatio ad hybridizatio istrumet desiged for slidebased fluorescece () ad chromogeic () i situ hybridizatio o histology ad cytology samples. The system reduces the umber of maual steps, ad improves efficiecy, throughput, ad precisio compared to maually performed ISH procedures. The has a 12-slide capacity ad heats ad cools slides through two temperature rages with short ramp times. The system is easy to use for a wide rage of probes ad protocols. The is optimized for DakoCytomatio DNA ad PNA probes for ad. Humidity Cotrol Strips The Humidity Cotrol Strips (code S2452, 20 strips) are specially desiged for the DakoCytomatio istrumet, ad esure cotrolled, high humidity durig the hybridizatio procedure. The strips cosist of a special hydrophilic polymer fiber material with high surface area ad the ability to quickly adsorb ad desorb moisture. cosistet Optimized for DakoCytomatio ad probes / Deaturatio Temperature / Time Hybridizatio Temperature / Time Code Probe Y5200 EBV (EBER) PNA Y1443 GePoit HPV * 92 C / 5 mi K5331 HER2 pharmdx * 82 C / 5 mi Y HPV DNA 92 C / 5 mi Y5202 Kappa/Lambda mrna PNA Y Split Sigal Traslocatio DNA 82 C / 5 mi Y5405 Sub-Deletio Sigal DNA 82 C / 5 mi Y1441 Telomerase (htr) 37 C / 2 hrs K Telomere PNA 80 C / 5 mi RT / 30 mi K5333 TOP2A pharmdx * 82 C / 5 mi *call for availability automatigworkflow The ca be itegrated withi the workflow for laboratories workig with the DakoCytomatio Autostaier or other DakoCytomatio systems.

5 Specificatios Slide Capacity Up to 12 slides per ru Program Capacity Storig up to 40 programs by ames ad umbers Program Optios Deaturatio ad hybridizatio Hybridizatio oly Fixed temperature Temperature Uiformity Withi +/- 1 C Deaturatio Temperature C, 0 30 miutes Hybridizatio Temperature Room temperature, C / 0 99 hours Fixed Temperature Room temperature, C / 0 99 hours Heatig Time C / 2 miutes Coolig Time C / 5 miutes Dimesios Depth: 451 mm (17 i); Width: 228 mm (9 i); Height: 140 mm (5 i) Weight 8.5 Kg Ambiet Operatig Temperature C Pre-Set Voltage V (S2450) or V (S2451) Frequecy Hz EXPANDING HORIZONS The spirit of DakoCytomatio lives i its commitmet to customers ad i its cotiuig efforts to expad horizos i patiet care. As research, sciece ad techology advace aroud the globe, DakoCytomatio embraces iovative breakthroughs from Life Scieces to Diagostics. A leadig i vitro diagostics compay specializig i the idetificatio of cacer markers, the compay offers a diverse product portfolio icludig reagets ad istrumetatio for aatomic ad molecular pathology, pharmacodiagostics ad flow cytometry. For further iformatio please cotact your local DakoCytomatio office: Australia Tel Fax Austria Tel Fax Belgium Tel Fax Caada Tel Fax Czech Republic Tel Fax Demark Tel Fax Frace Tel Fax Germay Tel Fax Irelad Tel Fax Italy Tel Fax Japa Tel Fax The Netherlads Tel Fax Corporate Headquarters: Demark Tel Fax Distributors i more tha 50 coutries Norway Tel Fax Polad Tel Fax Spai Tel Fax Swede Tel Fax Switzerlad Tel Fax Uited Kigdom Tel. (0) Fax (0) Techical Support Tel. (0) Uited States of America Tel Fax Customer Service Tel Techical Support Tel Flow Istrumetatio Tel Fax with product offerigs that cover the cotiuum Automate your ad procedures

6 Specificatios Slide Capacity Up to 12 slides per ru Program Capacity Storig up to 40 programs by ames ad umbers Program Optios Deaturatio ad hybridizatio Hybridizatio oly Fixed temperature Temperature Uiformity Withi +/- 1 C Deaturatio Temperature C, 0 30 miutes Hybridizatio Temperature Room temperature, C / 0 99 hours Fixed Temperature Room temperature, C / 0 99 hours Heatig Time C / 2 miutes Coolig Time C / 5 miutes Dimesios Depth: 451 mm (17 i); Width: 228 mm (9 i); Height: 140 mm (5 i) Weight 8.5 Kg Ambiet Operatig Temperature C Pre-Set Voltage V (S2450) or V (S2451) Frequecy Hz EXPANDING HORIZONS The spirit of DakoCytomatio lives i its commitmet to customers ad i its cotiuig efforts to expad horizos i patiet care. As research, sciece ad techology advace aroud the globe, DakoCytomatio embraces iovative breakthroughs from Life Scieces to Diagostics. A leadig i vitro diagostics compay specializig i the idetificatio of cacer markers, the compay offers a diverse product portfolio icludig reagets ad istrumetatio for aatomic ad molecular pathology, pharmacodiagostics ad flow cytometry. For further iformatio please cotact your local DakoCytomatio office: Australia Tel Fax Austria Tel Fax Belgium Tel Fax Caada Tel Fax Czech Republic Tel Fax Demark Tel Fax Frace Tel Fax Germay Tel Fax Irelad Tel Fax Italy Tel Fax Japa Tel Fax The Netherlads Tel Fax Corporate Headquarters: Demark Tel Fax Distributors i more tha 50 coutries Norway Tel Fax Polad Tel Fax Spai Tel Fax Swede Tel Fax Switzerlad Tel Fax Uited Kigdom Tel. (0) Fax (0) Techical Support Tel. (0) Uited States of America Tel Fax Customer Service Tel Techical Support Tel Flow Istrumetatio Tel Fax with product offerigs that cover the cotiuum Automate your ad procedures

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