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1 Skin Appendage Disord 3(1) 1 58 (2017) print ISSN online e-issn S. Karger Medical and Scientific Publishers Basel. Freiburg. Paris. London. New York. Chennai. New Delhi. Bangkok. Beijing. Shanghai. Tokyo. Kuala Lumpur. Singapore. Sydney

2 A valuable tool for clinical practice Current Problems in Dermatology : P. Itin, G.B.E. Jemec Vol. 52 Diagnosis and Therapy of Tattoo Complications With Atlas of Illustrative Cases J. Serup W. Bäumler Diagnosis and Therapy of Tattoo Complications With Atlas of Illustrative Cases Jørgen Serup Wolfgang Bäumler Diagnosis and Therapy of Tattoo Complications With Atlas of Illustrative Cases : Serup, J. (Copenhagen); Bäumler, W. (Regensburg) VIII p., 242 fig., 239 in color, 8 tab., 2017 CHF / EUR / USD Hard cover or online prices for personal customers Prices subject to change, VAT not included EUR price for eurozone countries, USD price for USA and Latin America only ISBN e-isbn Current Problems in Dermatology, Vol. 52 Series Editor: Itin, P. (Basel); Jemec, G.B.E. (Roskilde) ISSN / e-issn Listed in MEDLINE/Pubmed, Thomson Reuters indices Dear Librarian I have reviewed this publication and would like to recommend it for our library. Recommended by: Department: Tattooing breaches the skin and can, therefore, cause a variety of complications. This book covers the full spectrum of issues clinical practitioners may encounter when treating affected patients. Introductory chapters include educational information on methods for tattooing, types of tattoos, tattoo inks, and tattoo ink toxicology. The focus is on the diagnosis and classification of tattoo complications. In this regard, a comprehensive atlas of acute and chronic complications serves as a valuable tool. Further chapters summarize available therapies, their rationale, and indication. This includes various medical and surgical treatments with a review of dermatome shaving. Lastly, tattoo removal by gold standard YAG lasers and the more recent pico-second lasers is discussed with the optimal therapeutic outcome in mind. Dermatologists, plastic surgeons, general practitioners, laser surgeons, and other specialists treating tattoo complications will find this book to be an indispensable resource. It also includes information relevant for a broad range of stakeholders in the tattoo business, including authorities and regulators. Contents Preface: Serup, J.; Bäumler, W. From Technique of Tattooing to Biokinetics and Toxicology of Injected Tattoo Ink Particles and Chemicals: Serup, J. Individual Risk and Prevention of Complications: Doctors Advice to Persons Wishing a New Tattoo: Serup, J. Tattoo Infections, Personal Resistance, and Contagious Exposure through Tattooing: Serup, J. Diagnostic Tools for Doctors Evaluation of Tattoo Complications: Serup, J. How to Diagnose and Classify Tattoo Complications in the Clinic: A System of Distinctive Patterns: Serup, J. Medical Treatment of Tattoo Complications: Serup, J. Surgical Treatment of Tattoo Complications: Sepehri, M.; Jørgensen, B. Laser Treatment of Tattoos: Basic Principles: Bäumler, W. Removal of Tattoos by Q-Switched Nanosecond Lasers: Karsai, S. New and Advanced Picosecond Lasers for Tattoo Removals: Adatto, M.A.; Amir, R.; Bhawalkar, J.; Sierra, R.; Bankowski, R.; Rozen D.; Dierickx, C.; Lapidoth, M. Laser Surgeon, Client Education, and Satisfaction with Tattoo Removal: Hutton Carlsen, K.; Esmann, J.; Serup, J. Guide to Treatment of Tattoo Complications and Tattoo Removal: Serup, J.; Bäumler, W. Atlas of Illustrative Cases Index of Cases Author Index/Subject Index Date: Signature: Orders may be placed with any bookshop, subscription agency, directly with the publisher or through a Karger representative. The easiest way to order: Karger Medical and Scientific Publishers CH 4009 Basel, Switzerland orders@karger.com, f: KI17256

3 -in-chief Official Organ of Dimitris Rigopoulos National and Kapodistrian University of Athens, Athens, Greece Antonella Tosti University of Miami, Miami, USA Editorial Board Roberto Arenas Hospital General Dr Manuel Gea Gonzalez, Mexico City, Mexico Daniel Asz Sigall Private Practice Dermatology, Mexico City, Mexico Robert Baran University of Franche-Comté, Cannes, France Wilma Bergfeld Cleveland Clinic, Cleveland, USA Vincenzo Bettoli University of Ferrara, Ferrara, Italy Ulrike Blume-Peytavi Charité University Medicine Berlin, Berlin, Germany Anna Campanati Marche Polytechnic University, Ancona, Italy Ralph Daniel Private Practice Dermatology, Jackson, USA David de Berker Bristol Royal Infirmary, Bristol, UK James Q. Del Rosso Las Vegas Skin and Cancer Clinics, Henderson, USA Nilton Di Chiacchio Private Practice Dermatology, São Paulo, Brazil Zoe Diana Draelos Dermatology Consulting Services, High Point, USA Boni Elewski University of Alabama at Birmingham, Birmingham, USA Gabriella Fabbrocini University of Naples Federico II, Naples, Italy Harold Farber Center for Dermatology, Laser, and Cosmetic Surgery, Philadelphia, USA Steven Feldman Wake Forest University, Winston-Salem, USA Stamatis Gregoriou National and Kapodistrian University of Athens, Athens, Greece Ramon Grimalt International University of Catalonia, Sant Cugat del Vallès, Spain Aditya K. Gupta Mediprobe Research Inc, London, Canada Daniela Guzman-Sanchez d & laser clinic, Guadalajara, Mexico Eckart Haneke Private Practice Dermatology, Freiburg, Germany Maria K. Hordinsky University of Minnesota, Minneapolis, USA Dimitrios Ioannides Aristotle UniversityMedical School, Thessaloniki, Greece Matilde Iorizzo Private Practice Dermatology, Bellinzona, Switzerland Ana Kaminsky University of Buenos Aires, Buenos Aires, Argentina Alexandros Katoulis National and Kapodistrian University of Athens, Athens, Greece Dong-Youn Lee Samsung Medical Center, Seoul, Korea Printed in Germany on acid-free and non-aging paper (ISO 9706) by Stückle Druck, Ettenheim

4 Bryan C. Markinson Icahn School of Medicine at Mount Sinai, New York, USA Amy McMichael Wake Forest University, Winston-Salem, USA Andrew G. Messenger Royal Hallamshire Hospital, Sheffield, UK Giuseppe Micali University of Catania, Catania, Italy Mariya Miteva University of Miami, Miami, USA Bianca Maria Piraccini University of Bologna, Bologna, Italy Phoebe Rich Oregon Dermatology and Research Center, Portland, USA Bertrand Richert Université libre de Bruxelles, Brussels, Belgium Ricardo Romiti Universidade de São Paulo, São Paulo, Brazil Beth S. Ruben Palo Alto Medical Foundation, Palo Alto, USA Adam I. Rubin University of Pennsylvania Philadelphia, USA Lidia Rudnicka Medical University of Warsaw, Warsaw, Poland Richard K. Scher Cornell University, New York, USA Jerry Shapiro New York University, New York, USA Avner Shemer Tel-Aviv University, Tel Aviv, Israel Rodney Sinclair University of Melbourne, East Melbourne, Australia Catherine Stefanato St Thomas Hospital, London, UK Ralph M. Trüeb Private Practice Dermatology, Wallisellen, Switzerland Tracey Vlahovic Temple University, Philadelphia, USA Uwe Wollina Hospital Dresden-Friedrichstadt, Dresden, Germany Martin Zaiac Greater Miami Skin & Laser Center, Miami Beach, USA Abraham Zlotogorski Hadassah-Hebrew University Medical Center, Jerusalem, Israel Christos C. Zouboulis Dessau City Clinic, Dessau, Germany Printed in Germany on acid-free and non-aging paper (ISO 9706) by Stückle Druck, Ettenheim

5 Guidelines for Authors Aims and Scope Skin Appendage Disorders provides a wide range of original and review articles dealing with all aspects of hair, nail and skin glands. The section Novel Insights from Clinical Practice introduces special case examples and their treatments. Innovative therapies are presented under the heading Novel Treatments, and in Clinical Investigations the latest findings are discussed. A special highlight are the articles in the section Guidelines that present the consensus treatments, and which are a must-read for everyone who wants to stay up-to-date. The section Adnexal Surgery focuses on both established and approved as well as new surgical treatments. Pathological evaluation of skin appendage disorders requires specific training and the Pathology section will be open to original papers and reviews on this topic. Covering all aspects of the field, Skin Appendage Disorders is of primary importance for dermatologists in clinics and research, dermatological surgeons as well as cosmetic dermatologists. Submission Manuscripts in English are considered for publication and should be submitted online Should you experience any problems with your submission, please contact the Editorial Office at: sad@karger.com S. Karger AG Editorial Office Skin Appendage Disorders P.O. Box CH 4009 Basel (Switzerland) Tel Fax Conditions All manuscripts are subject to editorial review. Manuscripts are received with the explicit understanding that they are not under simultaneous consideration by any other publication. A cover letter with the name, address, and telephone and telefax numbers of the corresponding author must accompany each manuscript. This letter must include a statement that affirms that all authors concur with the submission. Submission of an article for publication implies transfer of the copyright from the author to the publisher upon acceptance. Accepted papers become the permanent property of Skin Appendage Disorders and may not be reproduced by any means, in whole or in part, without the written consent of the publisher. It is the author s responsibility to obtain permission to reproduce illustrations, tables, etc. from other publications. Peer-Review Policy Skin Appendage Disorders is a peer-reviewed journal. Our aim is to provide authors with fast and constructive feedback regarding their submitted manuscript. The Editor-in-Chief and international editorial board ensure a thorough and fair peer-review and the highest scientific publishing standards. The Editor-in-Chief is responsible to maintain high quality peer-review of papers submitted to the journal. Conflicts of Interest Authors are required to disclose any sponsorship or funding arrangements relating to their research and all authors should disclose any possible conflicts of interest. Conflict of interest statements will be published at the end of the article. Ethics Published research must comply with the guidelines for human studies and animal welfare regulations. Authors should state that subjects have given their informed consent and that the study protocol has been approved by the institute s committee on human research. Further, they should also state that animal experiments conform to institutional standards. Sections/Types of Papers Original Article Review Article Novel Insights from Clinical Practice Novel Treatments Clinical Investigations What Is Your Diagnosis? Guidelines Letter to the Editor Editorial Comment Adnexal Surgery Pathology Industry Corner Research papers should be submitted as Original Articles. Novel Insights from Clinical Practice: The publication space available for case reports is very limited. The journal only considers case reports with significant new insights or with an extremely unusual and memorable course. Highlighted boxes containing one or two bullet points on Established Facts (what is already known) and Novel Insights (what new information has been gained) are required and should be placed on the first page of the report. These should be selected so as to reinforce the novelty of the clinical observation. The text per box should be limited to 1 2 very short sentences. The manuscript should be presented with an abstract (unstructured, max. 200 words), followed by introduction, case report and discussion. What Is Your Diagnosis?: Select catchy title not disclosing the diagnosis. Page 1: Case Report and 1 2 illustrations and the question What Is Your Diagnosis? Page 2: The diagnosis followed by a short description of what diagnostic procedures were done to reach the diagnosis and the discussion with references. Include 3 5 keywords. Plagiarism Policy Whether intentional or not, plagiarism is a serious violation. We define plagiarism as a case in which a paper reproduces another work with at least 25% similarity and without citation. If evidence of plagiarism is found before/after acceptance or after publication of the paper, the author will be offered a chance for rebuttal. If the arguments are not found to be satisfactory, the manuscript will be retracted and the author sanctioned from publishing papers for a period to be determined by the responsible Editor(s). Arrangement Title page: The first page of each paper should indicate the title, the authors names, the institute where the work was conducted, and a short title for use as running head. Full address: The exact postal address of the corresponding author complete with postal code must be given at the bottom of the title page. Please also supply phone and fax numbers, as well as address. Key words: Please supply 3 10 key words in English that reflect the content of the paper. Abstract: Each paper needs an abstract in English of not more than 200 words. The abstract is of utmost importance. It should contain the following information: purpose of the study, procedures, results, conclusions and message of the paper. Footnotes: Avoid footnotes. Tables and illustrations: Tables and illustrations (both numbered in Arabic numerals) should be sent in separate files. Tables require a heading and figures a legend, also in a separate file. Due to technical reasons, figures with a screen background should not be submitted. When possible, group several illustrations in one block for reproduction (max. size 180 x 223 mm). 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There should be no punctuation other than a comma to separate the authors. Preferably, please cite all authors. Cite all authors, et al is not sufficient. Abbreviate journal names according to the Index Medicus system. Also see International Committee of Medical Journal : Uniform requirements for manuscripts submitted to biomedical journals ( Examples (a) Papers published in periodicals: Chatel J-M, Bernard H, Orson FM: Isolation and characterization of two complete Ara h 2 isoforms cdna. Int Arch Allergy Immunol 2003;131: (b) Papers published only with DOI numbers: Theoharides TC, Boucher W, Spear K: Serum interleukin-6 reflects disease severity and osteoporosis in mastocytosis patients. Int Arch Allergy Immunol DOI: / (c) Monographs: Matthews DE, Farewell VT: Using and Understanding Medical Statistics, ed 3, revised. Basel, Karger, S. Karger AG, Basel karger@karger.com The Guidelines for Authors are available at:

6 (d) Edited books: Tarou LR, Bloomsmith MA, Hoff MP, Erwin JM, Maple TL: The behavior of aged great apes; in Erwin JM, Hof PR (eds): Aging in Nonhuman Primates. Interdiscipl Top Gerontol. Basel, Karger, 2002, vol 31, pp Reference Management Software: Use of EndNote is recommended for easy management and formatting of citations and reference lists. Digital Object Identifier (DOI) S. Karger Publishers supports DOIs as unique identifiers for articles. A DOI number will be printed on the title page of each article. DOIs can be useful in the future for identifying and citing articles published online without volume or issue information. More information can be found at Supplementary Material Multimedia files and other supplementary files, directly relevant but not essential to the conclusions of a paper, enhance the online version of a publication and increase its visibility on the web. These files will undergo editorial review. 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7 General Information ISSN Print Edition: ISSN Online Edition: Journal Homepage: Publication Data: Skin Appendage Disorders is published 4 times a year. Volume 3 with 4 issues appears in Copyright: 2017 S. Karger AG, Basel (Switzerland). All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the journal is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Subscription Rates: Subscriptions run for a full calendar year. Prices are given per year. Personal subscription: Print or Online Print+Online combined CHF CHF EUR EUR USD USD postage and handling (added to print and print+online) CHF Europe, CHF Overseas EUR USD Institutional subscription: Print or Online Print+Online combined CHF CHF EUR EUR USD USD postage and handling (added to print and print+online) CHF Europe, CHF Overseas EUR USD Back Volumes and Single Issues: Information on availability and prices of single print issues and print or electronic back volumes can be obtained from Customer Service at service@karger.com. Subscription Orders: Orders can be placed at agencies, bookstores, directly with the Publisher S. Karger AG Medical and Scientific Publishers Allschwilerstrasse 10 CH 4009 Basel Switzerland t: f: e: karger@karger.com w: (for courier services only: Allschwilerstrasse 10 CH 4055 Basel) or further Karger offices or representatives: Germany S. Karger GmbH Postfach Freiburg Deutschland (Hausadresse: Wilhelmstrasse 20A, Freiburg) t: f: e: information@karger.de w: Japan Karger Japan, Inc. Shiba Daimon Asahi Bldg. 2F Shiba Daimon Minato-ku Tokyo Japan t: f: e: publisher@karger.jp w: USA S. Karger Publishers, Inc. 26 West Avon Road P.O. Box 529 Unionville, CT USA Toll free: t: f: e: kargerusa@karger.com France Enter & Read Albertine Luginbuhl 23, rue du Départ, boite Paris France t: +33 (0) e: albertineluginbuhl@orange.fr South East Asia, China and Taiwan Karger Regional Office (Malaysia) Level A, PJ Exchange No. 16A, Persiaran Barat Petaling Jaya Selangor Darul Ehsan Malaysia t: f: e: service@karger.cn; r.chew@karger.cn Karger China 51F Raffles City Centre 268 Xi Zang Middle Road Huang Pu District Shanghai P.R. China t: f: e: service@karger.cn r.chew@karger.cn w: India, Bangladesh, Sri Lanka Karger India Plot No. 17, Yusuf Sarai Market B.L. Glass Building, 2nd Floor Sri Aurobindo Marg New Delhi India t: f: c: e: r.kumar@kargerindia.com w: Change of Address: Both old and new address should be sent to the subscription source S. Karger AG, Basel karger@karger.com The Journal Home Page is available at:

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9 Contents See the journal website for contents Basel Freiburg Paris London New York New Delhi Bangkok Beijing Tokyo Kuala Lumpur Singapore Sydney

10 Three BMA awards for Karger Publishers We are delighted to announce that three Karger titles received Highly Commended awards by the British Medical Association in their prestigious 2016 Medical Book Competition: In the category Internal Medicine In the category Oncology Current Problems in Dermatology : P. Itin, G.B.E. Jemec Vol. 48 Tattooed Skin and Health J. Serup N. Kluger W. Bäumler Developments in Ophthalmology Editor: F. Bandello Vol. 55 Retinal Pharmacotherapeutics Quan Dong Nguyen Eduardo B. Rodrigues Michel Eid Farah William F. Mieler Diana V. Do Progress in Tumor Research (formerly Progress in Experimental Tumor Research) : R.A. Stahel, S. Peters Vol. 42 Immuno-Oncology O. Michielin G. Coukos Tattooed Skin and Health : Serup, J. (Copenhagen); Kluger, N. (Helsinki); Bäumler, W. (Regensburg) X p., 110 fig., 85 in color, 25 tab., hard cover, 2015 ISBN e-isbn Retinal Pharmacotherapeutics : Nguyen, Q.D. (Omaha, Nebr.); Rodrigues, E.B. (São Paulo); Farah, M.E. (São Paulo); Mieler, W.F. (Chicago, Ill.); Do, D.V. (Omaha, Nebr.) XVI p., 83 fig., 71 in color, 33 tab., hard cover, 2016 ISBN e-isbn Immuno-Oncology : Michielin, O.; Coukos, G. (Lausanne) VI p., 8 fig., 5 in color, 11 tab., hard cover, 2015 ISBN e-isbn Karger titles which received awards in previous BMA Medical Book Competitions Olszewski and Baxter s Cytoarchitecture of the Human Brainstem J.A. Büttner-Ennever A.K.E. Horn 3rd, revised and extended edition Progress in Respiratory Research Editor: C.T. Bolliger Vol. 38 Paediatric Bronchoscopy K.N. Priftis M.B. Anthracopoulos E. Eber A.C. Koumbourlis R.E. Wood Developments in Ophthalmology : F. Bandello, W. Behrens-Baumann Vol. 47 Macular Edema A Practical Approach Editor Gabriel Coscas Co- José Cunha-Vaz Anat Loewenstein Gisèle Soubrane KI

11 Editorial Comment 1 Comment on Robert Baran s Zakon Lecture, 2016 Rigopoulos, D. (Athens); Tosti, A. (Miami, FL) Zakon Lecture 2 Autobiography of a Loner Tackling the Nail Baran, R. (Cannes) Review Article 39 Botulinum Toxin Off-Label Use in Dermatology: A Review Campanati, A.; Martina, E.; Giuliodori, K.; Consales, V.; Bobyr, I.; Offidani, A. (Ancona) Original Articles 7 Common Allergens Identified Based on Patch Test Results in Patients with Suspected Contact Dermatitis of the Scalp Aleid, N.M. (Riyadh); Fertig, R.; Maddy, A.; Tosti, A. (Miami, FL) 15 An Update on the Disappearing Nail Bed Daniel, R.; Meir, B.; Avner, S. (Jackson, MS) 20 The Burden of Hidradenitis Suppurativa in a Cohort of Patients in Southern Finland: A Pilot Study Kluger, N. (Helsinki); Ranta, M.; Serlachius, M. (Espoo) Novel Insights from Clinical Practice 28 Recurrent Paronychia as a Presenting Manifestation of Pemphigus Vulgaris: A Case Report Zawar, V.; Pawar, M.; Kumavat, S. (Nashik) 36 Intermittent Chronic Telogen Effluvium Rebora, A. (Genoa) What Is Your Diagnosis? 18 Frontal Hairline Recession: A Diagnostic Pitfall Kelati, A.; Mernissi, F.Z. (Fez) 32 Asymptomatic Longitudinal Pachyxanthonychia of the Fingernail Reserva, J.L. (Maywood, IL); Ruben, B.S. (San Francisco, CA/ Palo Alto, CA); Venna, S.S. (Fairfax, VA) 57 Longitudinal Asymptomatic Xanthonychia Guerrero-González, G.A.; Robles-Mendez, J.C. (Monterrey); Saeb-Lima, M. (Mexico City); Di Chiacchio, N.G. (São Paulo); Vázquez-Martínez, O.; Ocampo-Candiani, J. (Monterrey)